Article
Psychiatry
Sowmya Selvaraj, Harleen Chhabra, Damodharan Dinakaran, Vanteemar S. Sreeraj, Shivakumar Venkataram, Janardhanan C. Narayanaswamy, Muralidharan Kesavan, Shivarama Varambally, Ganesan Venkatasubramanian
Summary: The study findings support the pathogenetic role of ASD in AVH in SZ. Lack of effect on ASD following single-session tDCS suggests the need for multi-session studies in the future.
PSYCHIATRY RESEARCH
(2021)
Article
Behavioral Sciences
Theresa M. Marschall, Branislava Curcic-Blake, Sanne G. Brederoo, Remco J. Renken, Mascha M. J. Linszen, Sanne Koops, Iris E. C. Sommer
Summary: The study found that auditory hallucinations are common in people with hearing impairment. The research revealed significant differences in brain activity patterns between complex and simple auditory hallucinations, shedding light on the mechanisms behind these phenomena.
Article
Psychiatry
Johanna C. Badcock, Rachel Brand, Neil Thomas, Mark Hayward, Georgie Paulik
Summary: This study found that 72.1% of clients reported experiencing multimodal hallucinations in the past month. Both multimodal and unimodal hallucination groups showed improvement in distress and frequency of hallucinations post-treatment, with no significant group differences in treatment outcomes. Within the subgroup reporting ongoing effects of traumatic events, clients with multimodal hallucinations had significantly higher posttraumatic stress symptoms.
PSYCHIATRY RESEARCH
(2021)
Article
Neurosciences
Brian A. Coffman, Mark T. Curtis, Alfredo Sklar, Dylan Seebold, Dean F. Salisbury
Summary: Attentional control of auditory N100/M100 gain is reduced in individuals with first-episode psychosis (FEP). Persistent problems with executive modulation of auditory sensory activity may impact multiple aspects of psychosis. Our study found deficits in attentional M100 gain modulation in auditory cortex in FEP, and these deficits improved over time along with symptom severity.
HUMAN BRAIN MAPPING
(2023)
Article
Biology
Katharine N. Thakkar, Daniel H. Mathalon, Judith M. Ford
Summary: This paper discusses perception as an active process involving analysis by synthesis, imagination, and hallucinations without sensory stimulation, particularly focusing on auditory-verbal hallucinations. The authors propose that sense of agency for imagining is key to understanding different forms and features of hallucinations, outlining the neural, cognitive, and phenomenological consequences of this sense. Ultimately, the paper suggests that predictive processing can incorporate observations on sense of agency, imagination, and hallucination within a comprehensive framework for action, perception, and belief.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Article
Neuroimaging
Chuanjun Zhuo, Bo Xiao, Ce Chen, Deguo Jiang, Gongying Li, Xiaoyan Ma, Ranli Li, Lina Wang, Yong Xu, Chunhua Zhou, Xiaodong Lin
Summary: Untreated first episode schizophrenic patients with combined auditory and visual hallucinations exhibit alterations in brain structure and function, as well as retinal abnormalities. The majority of these patients show reduced gray matter volume, increased global functional connectivity density, and thinning of the retina compared to healthy controls.
BRAIN IMAGING AND BEHAVIOR
(2021)
Article
Clinical Neurology
Will H. Strawson, Hao-Ting Wang, Lisa Quadt, Maxine Sherman, Dennis E. O. Larsson, Geoff Davies, Bronte L. A. Mckeown, Marta Silva, Sarah Fielding-Smith, Anna-Marie Jones, Mark Hayward, Jonathan Smallwood, Hugo D. Critchley, Sarah N. Garfinkel
Summary: This study characterized auditory verbal hallucinations (AVH) in individuals with borderline personality disorder (BPD) using diverse methods including auditory detection tasks and functional neuroimaging. The results showed that AVH in BPD are caused by aberrant perceptual-cognitive mechanisms, experienced subjectively as persecutory and distressing, and associated with distinct patterns of neural activity.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
(2022)
Article
Psychiatry
Catalina Mourgues, Allison Hammer, Victoria Fisher, Eren Kafadar, Brittany Quagan, Claire Bien, Hale Jaeger, Rigi Thomas, Ely Sibarium, Alyson M. Negreira, Elif Sarisik, Vasishta Polisetty, Hatice Nur Eken, Ayyub Imtiaz, Halsey Niles, Andrew D. Sheldon, Albert R. Powers
Summary: Auditory verbal hallucinations (AVH) often cause distress and dysfunction, and conventional treatments may not be effective. Some voice-hearers report being able to fully control the onset and offset of their AVH, reducing disruption. The Yale control over perceptual experiences (COPE) Scales reliably measure voice-hearers' control over AVH and this ability is associated with positive clinical outcomes.
SCHIZOPHRENIA BULLETIN
(2022)
Review
Physiology
Hong-Viet V. Ngo, Henrik Oster, Christina Andreou, Jonas Obleser
Summary: Circadian rhythms are inherent in all organisms and have an impact on various aspects of physiology and behavior in response to the 24-hour day-night cycle. The review focuses on the potential role of circadian disruption in auditory hallucinations, a cardinal symptom of psychosis. The dysbalance in excitation and inhibition within cortical networks, leading to disinhibition of dopaminergic signaling, is highlighted as a central physiological mechanism. Two avenues for experimentally intervening on circadian influences to alleviate hallucinations in psychotic disorders are proposed.
Review
Clinical Neurology
Alessandro Furia, Laura Licchetta, Lorenzo Muccioli, Lorenzo Ferri, Barbara Mostacci, Stefania Mazzoni, Veronica Menghi, Raffaella Minardi, Paolo Tinuper, Francesca Bisulli
Summary: Epilepsy with auditory features (EAF) is a focal epilepsy characterized by seizures with auditory aura or receptive aphasia, suggesting involvement of the lateral temporal lobe. The etiology of EAF is largely unknown, but familial and sporadic cases share similar clinical characteristics with only a few having a documented genetic cause. Patients with EAF usually have a normal neurological examination and respond well to antiseizure medications. However, remission rates may be lower than expected and treatment withdrawal can lead to relapses.
FRONTIERS IN NEUROLOGY
(2022)
Review
Psychiatry
Wen-Long Jiang, Dong-Bin Cai, Chen-Hui Sun, Fei Yin, Stephan Goerigk, Andre Russowsky Brunoni, Xi-Wu Zhao, Taryn L. Mayes, Wei Zheng, Yu-Tao Xiang
Summary: This study conducted a Meta-analysis on treatment-refractory auditory hallucinations in schizophrenia patients and found that active transcranial direct current stimulation (tDCS) did not show significant advantage in improving auditory hallucinations compared to sham stimulation. However, subgroup analyses revealed that active tDCS with twice-daily stimulation or with >= 10 stimulation sessions showed a significantly better therapeutic effect in improving auditory hallucinations symptoms.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Psychiatry
Esther Lorente-Rovira, Eva Grasa, Susana Ochoa, Iluminada Corripio, Trinidad Pelaez, Raquel Lopez-Carrilero, Angela Gutierrez-Gea, Maria Morano-Guillen, Jose M. Villagran, Agna A. Bartels-Velthuis, Jack A. Jenner, Julio Sanjuan
Summary: This study aims to examine the psychometric characteristics of two different and complementary instruments for assessing auditory hallucinations in patients with schizophrenia or schizoaffective disorder. The results show that both Spanish versions of the instruments have good internal consistency, reliability, validity, and acceptance among patients.
REVISTA DE PSIQUIATRIA Y SALUD MENTAL
(2022)
Article
Clinical Neurology
Minglan Yu, Yanhong Du, Kezhi Liu, Xuemei Liang, Chaohua Huang, Rongfang He, Wei Lei, Jing Chen, Jianlin Chen, Youguo Tan, Bo Xiang
Summary: The study reveals significant genetic correlations between auditory hallucinations and insomnia complaints, sleep duration, and ease of getting up in the morning. There is a high genetic correlation between visual hallucinations and insomnia complaints. Mendelian randomization indicates a unidirectional causal relationship between sleep duration and auditory hallucinations, suggesting that addressing sleep problems should be a priority in mental health services.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Pablo Lopez-Silva, Alvaro Cavieres, Clara Humpston
Summary: This paper discusses the extensive phenomenological variation of first-personal reports on auditory verbal hallucinations, introduces the concept of pseudohallucination to describe hallucinatory-like phenomena that do not exhibit paradigmatic features of genuine hallucinations, and explores the inner/outer distinction proposed by Karl Jaspers. The concept of pseudohallucination has received criticism but the inner/outer distinction remains a challenge for dominant theories about the neurocognitive origin of auditory verbal hallucinations.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychiatry
Wei Lin Toh, Mikaela Bere, Susan L. Rossell
Summary: The study explores the interest in hallucinations across multiple senses in psychosis and distinguishes between the concepts of multimodal hallucinations and multisensory hallucinations. The importance of temporality and relatedness in delineating these experiences is emphasized in the research.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2022)
