期刊
CURRENT OPINION IN VIROLOGY
卷 7, 期 -, 页码 1-10出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2014.03.004
关键词
-
类别
资金
- Canadian Institutes of Health Research (CIHR) [232063]
- NSERC
- National CIHR Research Training Program in Hepatitis C
- Alberta Innovates [201201140] Funding Source: researchfish
It is well-established that the host microRNA (miRNA) milieu has a significant influence on the etiology of disease. In the context of viruses, such as hepatitis C virus (HCV), microRNAs have been shown to influence viral life cycles both directly, through interactions with the viral genome, and indirectly, through regulation of Critical virus-associated host pathways. Several miRNA profiling studies have demonstrated that HCV infection aberrantly regulates a significant number of human miRNA. However, the biological relevance of these modulations remains poorly understood. In this review, we summarize recent research that has shed light on the pro-viral and anti-viral roles of HCV-induced changes in human miRNA expression and their significance in the development of HCV related sequelae and response to therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据