期刊
CURRENT OPINION IN VIROLOGY
卷 4, 期 -, 页码 71-77出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2013.11.004
关键词
-
类别
资金
- Wellcome Trust [098051]
- Medical Research Council [G1000413]
- BBSRC [BB/L00397X/1] Funding Source: UKRI
- MRC [MC_UU_12018/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/L00397X/1] Funding Source: researchfish
- Medical Research Council [MC_UU_12018/1, 975284, 1223252] Funding Source: researchfish
Interferon inducible transmembrane (IFITM) proteins are a recently discovered family of cellular anti-viral proteins that restrict the replication of a number of enveloped and non-enveloped viruses. IFITM proteins are located in the plasma membrane and endosomal membranes, the main portals of entry for many viruses. Biochemical and membrane fusion studies suggest IFITM proteins have the ability to inhibit viral entry, possibly by modulating the fluidity of cellular membranes. Here we discuss the IFITM proteins, recent work on their mode of action, and future directions for research.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据