标题
Antagonism of mTOR Activity by a Kinetically Inert Rhodium(III) Complex
作者
关键词
-
出版物
ChemPlusChem
Volume 79, Issue 4, Pages 508-511
出版商
Wiley
发表日期
2014-02-16
DOI
10.1002/cplu.201400014
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Bioactive Luminescent Transition-Metal Complexes for Biomedical Applications
- (2013) Dik-Lung Ma et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- PI3K/Akt/mTOR pathway inhibitors in the therapy of pancreatic neuroendocrine tumors
- (2013) Edward M. Wolin CANCER LETTERS
- Metal complexes as inhibitors of transcription factor activity
- (2013) Chung-Hang Leung et al. COORDINATION CHEMISTRY REVIEWS
- Bioactive iridium and rhodium complexes as therapeutic agents
- (2013) Chung-Hang Leung et al. COORDINATION CHEMISTRY REVIEWS
- Therapeutic Implications of mTOR Inhibitors in the Treatment of Gastric Cancer
- (2013) Zhaode Bu et al. CURRENT CANCER DRUG TARGETS
- Current Status and Future Perspectives of PI3K and mTOR Inhibitor as Anticancer Drugs in Breast Cancer
- (2013) Xiaobei Zhang et al. CURRENT CANCER DRUG TARGETS
- Targeted delivery of platinum-based anticancer complexes
- (2013) Jennifer S Butler et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Protein–protein interactions as druggable targets: recent technological advances
- (2013) Alicia P Higueruelo et al. CURRENT OPINION IN PHARMACOLOGY
- Next-Generation Metal Anticancer Complexes: Multitargeting via Redox Modulation
- (2013) Isolda Romero-Canelón et al. INORGANIC CHEMISTRY
- Inhibition of α-helix-mediated protein–protein interactions using designed molecules
- (2013) Valeria Azzarito et al. Nature Chemistry
- Enzyme inhibition by metal complexes: concepts, strategies and applications
- (2013) Kelly J. Kilpin et al. Chemical Science
- Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery?
- (2012) Philipp Thiel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Metal-Based Inhibitor of Tumor Necrosis Factor-α
- (2012) Chung-Hang Leung et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Designing organometallic compounds for catalysis and therapy
- (2012) Anna Louisa Noffke et al. CHEMICAL COMMUNICATIONS
- Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs
- (2012) Wukun Liu et al. CHEMICAL SOCIETY REVIEWS
- Bioactive cyclometalated phthalimides: design, synthesis and kinase inhibition
- (2012) Sebastian Blanck et al. DALTON TRANSACTIONS
- Pyridocarbazole-Rhodium(III) Complexes as Protein Kinase Inhibitors
- (2012) Sandra Dieckmann et al. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction
- (2012) Hacer Karatas et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Metal-Based Inhibitor of NEDD8-Activating Enzyme
- (2012) Hai-Jing Zhong et al. PLoS One
- Structural biology and drug discovery for protein–protein interactions
- (2012) Harry Jubb et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Inhibition of Janus kinase 2 by cyclometalated rhodium complexes
- (2012) Chung-Hang Leung et al. MedChemComm
- Antitumor Efficacy of PKI-587, a Highly Potent Dual PI3K/mTOR Kinase Inhibitor
- (2011) R. Mallon et al. CLINICAL CANCER RESEARCH
- Metal-based antitumour drugs in the post-genomic era: what comes next?
- (2011) Gianni Sava et al. DALTON TRANSACTIONS
- Targeting the mTOR kinase domain: the second generation of mTOR inhibitors
- (2011) Yan-Jie Zhang et al. DRUG DISCOVERY TODAY
- Discovery of 9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a Potent, Selective, and Orally Available Mammalian Target of Rapamycin (mTOR) Inhibitor for Treatment of Cancer
- (2011) Qingsong Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors
- (2011) Sebastian Blanck et al. ORGANOMETALLICS
- Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β
- (2010) G. Ekin Atilla-Gokcumen et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer
- (2010) Qingsong Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound26(PKI-587), a Highly Efficacious Dual Inhibitor
- (2010) Aranapakam M. Venkatesan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Organometallic Anticancer Compounds
- (2010) Gilles Gasser et al. JOURNAL OF MEDICINAL CHEMISTRY
- mTOR signaling and drug development in cancer
- (2010) Janet Dancey Nature Reviews Clinical Oncology
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy
- (2010) C A Sparks et al. ONCOGENE
- Targeting proteins with metal complexes
- (2009) Eric Meggers CHEMICAL COMMUNICATIONS
- Inhibition of protein–protein interactions using designed molecules
- (2009) Andrew J. Wilson CHEMICAL SOCIETY REVIEWS
- Molecular mechanisms of mTOR-mediated translational control
- (2009) Xiaoju Max Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy
- (2008) Sanjeev Shangary et al. Annual Review of Pharmacology and Toxicology
- Platinum(II) Complexes with Dipyridophenazine Ligands as Human Telomerase Inhibitors and Luminescent Probes for G-Quadruplex DNA
- (2008) Dik-Lung Ma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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