Strategies for gene disruption in Drosophila

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair inDrosophila

(2014) Scott J. Gratz et al.   GENETICS

Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease

(2013) Scott J. Gratz et al.   GENETICS

Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila

(2013) Shu Kondo et al.   GENETICS

Highly Efficient Genome Modifications Mediated by CRISPR/Cas9 in Drosophila

(2013) Z. Yu et al.   GENETICS

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

(2013) Prashant Mali et al.   NATURE BIOTECHNOLOGY

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

(2013) Vikram Pattanayak et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

(2013) Thomas J. Cradick et al.   NUCLEIC ACIDS RESEARCH

A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly

(2013) Shijia Chen et al.   NUCLEIC ACIDS RESEARCH

Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System

(2013) Andrew R. Bassett et al.   Cell Reports

W::Neo: A Novel Dual-Selection Marker for High Efficiency Gene Targeting in Drosophila

(2012) Wenke Zhou et al.   PLoS One

Systematic Discovery of Rab GTPases with Synaptic Functions in Drosophila

(2011) Chih-Chiang Chan et al.   CURRENT BIOLOGY

TheDrosophilaGene Disruption Project: Progress Using Transposons With Distinctive Site Specificities

(2011) Hugo J. Bellen et al.   GENETICS

MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes

(2011) Koen J T Venken et al.   NATURE METHODS

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

(2011) Vikram Pattanayak et al.   NATURE METHODS

Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

(2011) U. B. Pandey et al.   PHARMACOLOGICAL REVIEWS

Drosophila P elements preferentially transpose to replication origins

(2011) A. C. Spradling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Splinkerette PCR for Mapping Transposable Elements in Drosophila

(2010) Christopher J. Potter et al.   PLoS One

Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors

(2010) R. Morbitzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of EMS-Induced Mutations in Drosophila melanogaster by Whole-Genome Sequencing

(2009) J. P. Blumenstiel et al.   GENETICS

Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster

(2009) Koen J T Venken et al.   NATURE METHODS

DrosophilaModels of Neurodegenerative Diseases

(2008) Bingwei Lu et al.   Annual Review of Pathology-Mechanisms of Disease

Efficient Ends-Out Gene Targeting In Drosophila

(2008) J. Huang et al.   GENETICS

A powerful method combining homologous recombination and site-specific recombination for targeted mutagenesis in Drosophila

(2008) G. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA