Article
Obstetrics & Gynecology
Erin K. Collier, Ram K. Parvataneni, Michelle A. Lowes, Haley B. Naik, Martin Okun, Vivian Y. Shi, Jennifer L. Hsiao
Summary: Hidradenitis suppurativa disproportionately affects women of childbearing age and is characterized by painful nodules and abscesses. Early recognition and treatment are crucial to reduce long-term sequelae and improve patient comfort during examinations.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Obstetrics & Gynecology
Adeyemi A. Ogunleye, Idorenyin E. Ndem, Helen Bui, Christopher J. Sayed
Summary: Hidradenitis suppurativa is a chronic, inflammatory disorder with underreported prevalence and unknown pathogenesis, leading to variable approaches in clinical management. Early diagnosis and treatment are crucial for better disease control and minimizing associated morbidity. Knowledge of vulvoperineal hidradenitis is essential for gynecologists and primary care physicians for optimal patient outcomes.
OBSTETRICAL & GYNECOLOGICAL SURVEY
(2021)
Article
Obstetrics & Gynecology
Christopher J. Sayed, Jennifer L. Hsiao, Martin M. Okun
Summary: Hidradenitis suppurativa is a chronic inflammatory skin disease that is more prevalent in women and individuals aged 18-40 years. Obstetrician-gynecologists have the opportunity to reduce morbidity by diagnosing and optimizing treatment early.
OBSTETRICS AND GYNECOLOGY
(2021)
Review
Emergency Medicine
Martin M. Okun, Avram Flamm, Elizabeth Barrall Werley, Joslyn S. Kirby
Summary: Hidradenitis suppurativa (HS) is an immune-mediated inflammatory skin disease that poses diagnostic challenges. This article discusses how emergency departments can educate and treat patients with HS and coordinate care with other physicians. The review provides updates on the epidemiology, diagnosis, and management of HS.
JOURNAL OF EMERGENCY MEDICINE
(2022)
Review
Allergy
Kelsey R. van Straalen, Errol P. Prens, Johann E. Gudjonsson
Summary: Hidradenitis suppurativa is a chronic, inflammatory skin disorder that affects around 1% of the population and significantly impacts patients' quality of life. It is characterized by inflammatory lesions such as nodules, abscesses, and sinus tracts in areas like the armpits, groin, and buttocks, typically appearing during or after puberty. The development and maintenance of the disease involve a complex interplay of genetic predisposition, hormonal factors, obesity, and smoking. It is believed to stem from a defect in the hair follicle, leading to follicular plugging, cyst formation, and subsequent acute inflammation. Over time, acute lesions progress to a chronic condition with draining sinus tracts and extensive fibrosis. Hidradenitis suppurativa is associated with other immune-mediated inflammatory diseases, metabolic and cardiovascular disorders, and psychiatric comorbidities.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2022)
Article
Dermatology
S. Wright, A. Strunk, A. Garg
Summary: The study revealed that baseline BMI and rate of BMI change are risk factors for developing HS, with a stronger influence among female and younger patients.
BRITISH JOURNAL OF DERMATOLOGY
(2021)
Review
Medicine, General & Internal
Amit Garg, Haley B. Naik, Joslyn S. Kirby
Summary: Hidradenitis suppurativa is a chronic, progressive inflammatory disease of the skin, often underdiagnosed or misdiagnosed. This review provides a comprehensive overview of the disease's clinical presentation, associated comorbidities, and life impact. It aims to facilitate earlier identification, differentiation from mimickers, and timely referrals for multidisciplinary management.
AMERICAN JOURNAL OF MEDICINE
(2023)
Article
Dermatology
Jurr Boer, Gregor B. E. Jemec
Summary: The mechanism behind the formation of localized patterns of inflammatory skin diseases such as Hidradenitis suppurtiva remains unclear, but it may be related to mechanical stress in intertriginous areas. The Koebner phenomenon describes the appearance of skin lesions following trauma, with striae distensae being a form of dermal scarring. The interaction between striae distensae and mechanical stress may provide a model for lesion development.
EXPERIMENTAL DERMATOLOGY
(2021)
Article
Dermatology
Kevin T. Savage, Vinita Singh, Zarine S. Patel, Christine A. Yannuzzi, Anne Marie McKenzie-Brown, Michelle A. Lowes, Lauren A. Orenstein
Summary: While specific data for HS pain management is lacking, categorizing HS pain as acute or chronic, nociceptive or neuropathic provides a framework for applying external pain management practices to HS treatment.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Editorial Material
Dermatology
Terri Shih, Devea De, Steven D. Daveluy, Marcia Hogeling, Michelle A. Lowes, Christopher Sayed, Vivian Y. Shi, Jennifer L. Hsiao
Summary: In determining biologic candidacy for patients with HS, it is proposed to shift away from Hurley staging and consider other variables. Biologics are a long-term treatment option for HS and may modify the disease. Factors to consider in clinical practice include previous treatment failures, disease progression, impact on patients' functional status and quality of life, and comorbidities.
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
(2022)
Review
Pediatrics
Colleen H. H. Cotton, Stella X. X. Chen, Sadaf H. H. Hussain, Irene Lara-Corrales, Andrea L. L. Zaenglein
Summary: Hidradenitis suppurativa is a chronic inflammatory skin disorder mainly affecting areas with apocrine glands. It is common in Western populations, occurring in up to 2% of people, and its incidence is increasing in children and adults. Pediatric cases represent about one-third of all cases, with initial symptoms often appearing in childhood. Limited clinical studies and guidelines exist for pediatric hidradenitis suppurativa. This review covers the epidemiology, clinical presentation, comorbidities, and management of the disease in children. It also discusses the barriers to timely diagnosis and the significant physical and emotional impact on children and adolescents.
Review
Medicine, General & Internal
Ratnakar Shukla, Priyanka Karagaiah, Anant Patil, Katherine Farnbach, Alex G. Ortega-Loayza, Thrasivoulos Tzellos, Jacek C. Szepietowski, Mario Giulini, Hadrian Schepler, Stephan Grabbe, Mohamad Goldust
Summary: HS is a chronic inflammatory disease that typically begins in puberty and presents with painful nodules and sinus tracts. The disease may impact quality of life and management often requires a multidisciplinary approach. Medical treatment can be used in early stages while surgical intervention may be necessary in advanced stages.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Dermatology
Amit Garg, Neeta Malviya, Andrew Strunk, Shari Wright, Afsaneh Alavi, Raed Alhusayen, Ali Alikhan, Steven D. Daveluy, Isabelle Delorme, Noah Goldfarb, Wayne Gulliver, Iltefat Hamzavi, Tarannum Jaleel, Alexa B. Kimball, Joslyn S. Kirby, Mark G. Kirchhof, Janice Lester, Hadar Lev-Tov, Michelle A. Lowes, Robert Micheletti, Lauren A. Orenstein, Vincent Piguet, Christopher Sayed, Jerry Tan, Haley B. Naik
Summary: This study aims to provide evidence-based screening recommendations for comorbidities associated with HS. Screening recommendations were made based on the consistency and quality of existing studies, disease prevalence and magnitude of association, as well as benefits, harms, and feasibility of screening. A total of 30 comorbidities were recommended for screening in order to improve patients' quality of life and health status.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Review
Dermatology
Ellie Choi, Xue Ting Ooi, Nisha Suyien Chandran
Summary: Interest and research in hidradenitis suppurativa (HS) have grown in the past decade, expanding knowledge about associated comorbidities and treatment efficacy. Limited understanding exists about pediatric-onset HS, but with increasing prevalence of childhood obesity and awareness of HS, physicians may encounter younger HS patients more frequently.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Review
Dermatology
Milosz Lewandowski, Zuzanna Swierczewska, Wioletta Baranska-Rybak
Summary: Hidradenitis suppurativa is a chronic inflammatory skin disease that severely affects patients' quality of life. While there are multiple treatment options, no uniformly effective therapy has been found. A multidisciplinary approach is needed for the management of this disease.
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2022)
