Article
Infectious Diseases
Lauriane Harrington, Emmanuel Aris, Amit Bhavsar, Nicolas Jamet, Esse Ifebi Herve Akpo, Jason C. Simeone, Anna Ramond, Dimitra Lambrelli, John Oppenheimer, Yan Sergerie, Piyali Mukherjee, Kinga Meszaros
Summary: This retrospective cohort study assessed the incidence rate of pertussis among individuals aged >= 50 years in the United Kingdom. The results showed a pertussis incidence rate of 5.8 per 100,000 person-years. Significant increases in healthcare resource utilization and direct medical costs were observed in the months surrounding the pertussis diagnosis, highlighting the need for increased awareness and pertussis booster doses among adults aged >= 50 years.
INFECTIOUS DISEASES AND THERAPY
(2023)
Article
Pediatrics
Yincent Tse, David Tuthill
Summary: This study estimated the incidence, characteristics and outcomes of medication errors in children aged 10-fold or greater or a tenth or less. It found that 10-fold errors in children were rare, sometimes prevented, and uncommonly caused harm. The study recommends country-wide improvements be made to reduce iatrogenic harm and understanding enabling and preventive factors may help national improvement strategies to reduce these errors.
ARCHIVES OF DISEASE IN CHILDHOOD
(2021)
Article
Public, Environmental & Occupational Health
Alastair D. Munro, Matthew Smallman-Raynor, Adam C. Algar
Summary: This study provides the first spatially explicit analysis of the temporal changes in endemic threshold populations for pertussis in two dynamic regions of England and Wales, revealing that mass vaccination led to a considerable increase in threshold size. Significant growth in fadeout duration was observed in the vaccine era, indicating geographical synchronisation of epidemic activity.
SOCIAL SCIENCE & MEDICINE
(2021)
Article
Medicine, General & Internal
Pauline Versteegen, Marta Valente Pinto, Alex M. Barkoff, Pieter G. M. van Gageldonk, Jan van de Kassteele, Marlies A. van Houten, Elisabeth A. M. Sanders, Ronald de Groot, Dimitri A. Diavatopoulos, Sagida Bibi, Raakel Luoto, Qiushui He, Anne-Marie Buisman, Dominic F. Kelly, Jussi Mertsola, Guy A. M. Berbers
Summary: The study investigated the response to acellular pertussis booster vaccination in different age groups and found that serum IgG levels increased significantly in all age groups at 28 days post-vaccination but decreased by 1 year. There was no consistent relationship between age and IgG response patterns, while IgA antibodies increased with age. Acellular boosters could be considered for older adults to reduce the burden of pertussis.
Article
Public, Environmental & Occupational Health
Ruth McDonald
Summary: This paper examines the emergence of self-employed care entrepreneurs in the home care field and the challenges they face due to changes in field structures and altered practices of care. It highlights the role of local state actors, their mobilisation of relevant capital, and the shaping of their habitus in this process. The changes threaten the distribution of capital in the home care field, but for care entrepreneurs, even a partial revolution is better than none at all.
SOCIOLOGY OF HEALTH & ILLNESS
(2023)
Article
Infectious Diseases
Enas Bahar, Daria Shamarina, Yan Sergerie, Piyali Mukherjee
Summary: Whooping cough continues to circulate among older adults in Europe, indicating that current vaccination strategies are insufficient. The implementation of standardized pertussis surveillance programs and strengthened vaccination for older adults are necessary.
INFECTIOUS DISEASES AND THERAPY
(2022)
Article
Clinical Neurology
James J. J. Sun, Lance Watkins, William Henley, Richard Laugharne, Heather Angus-Leppan, Indermeet Sawhney, Meissam Moghaddassian Shahidi, Kiran Purandare, Mogbeyiteren Eyeoyibo, Mark Scheepers, Geraldine Lines, Robert Winterhalder, Bhathika Perera, Benjamin Hyams, Samantha Ashby, Rohit Shankar
Summary: This study aimed to measure associations between risk factors for death in people with epilepsy (PWE) and intellectual disabilities (ID). The results showed that people who died had a higher prevalence of genetic conditions, older age, poor physical health, generalized tonic-clonic seizures, polypharmacy (not antiseizure medications) and antipsychotic use. The lack of an epilepsy review in the last 12 months, age over 50, medical condition prevalence, and antipsychotic medication use were identified as associated with increased risk of epilepsy-related death.
JOURNAL OF NEUROLOGY
(2023)
Article
Immunology
Pauline Versteegen, Axel A. Bonacic Marinovic, Pieter G. M. van Gageldonk, Saskia van der Lee, Lotte H. Hendrikx, Elisabeth A. M. Sanders, Guy A. M. Berbers, Anne-Marie Buisman
Summary: This study found that after a pertussis booster vaccination, adults had higher immune responses to pertussis compared to children, but the adaptability was poorer. Serum parameters indicative of recent pertussis infection were more commonly found in children primed with acellular pertussis vaccines.
Article
Geriatrics & Gerontology
Jung-Hyun Choi, Jaime Correia de Sousa, Monica Fletcher, Giovanni Gabutti, Lauriane Harrington, Michael Holden, Hyungwoo Kim, Jean-Pierre Michel, Piyali Mukherjee, Terry Nolan, Tobias Welte, Stefania Maggi
Summary: Despite effective paediatric vaccination programmes, pertussis remains a global health problem. The burden of pertussis in adults is underestimated and vaccine coverage rates are suboptimal. Measures to improve uptake of pertussis vaccines include strengthening immunisation guidelines, involving healthcare professionals, vaccination centres and pharmacies, and improving public knowledge of the disease.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Nusrat Khan, Christos Chalitsios, Yvonne Nartey, Glenn Simpson, Francesco Zaccardi, Miriam Santer, Paul J. Roderick, Beth Stuart, Andrew J. Farmer, Hajira Dambha-Miller
Summary: This study classified individuals with multiple long-term conditions (MLTC) and social care needs (SCN) into distinct clusters and quantified the association between these clusters and care outcomes. The findings highlight the risk of worse care outcomes, such as nursing home admission, for certain individuals. Distinct clusters based on shared sociodemographic characteristics can help identify at-risk individuals with MLTC and SCN at the primary care level.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2023)
Article
Pathology
Karen Fritchie, Lu Wang, Zhaohong Yin, Joy Nakitandwe, Dale Hedges, Andrew Horvai, Jorge Torres Mora, Andrew L. Folpe, Armita Bahrami
Summary: Lipoblastomas may occur in older children and adults and may be difficult to recognize due to their predominantly adipocytic or fibrous appearance.
Article
Public, Environmental & Occupational Health
Aliya Amirova, Katharine A. Rimes, Ruth A. Hackett
Summary: This study examines differences in perceived discrimination across multiple characteristics in middle- and older-aged adults in England and the United States. The results show that perceived discrimination due to financial status and sexual orientation is more prevalent in England, while more women perceive sex-based discrimination in the US. The study suggests that country-specific and socioeconomic factors influence the prevalence of perceived discrimination.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Gerontology
Christina R. Victor, Christine Dobbs, Kenneth Gilhooly, Vanessa Burholt
Summary: The prevalence of loneliness varies among different ethnic groups, with the Chinese group having the highest levels. Factors such as marriage, younger age, and low financial strain are protective against loneliness, while number of children, gender, and health rating are not associated with loneliness. Ethnicity did not significantly impact loneliness vulnerability factors in this study.
EUROPEAN JOURNAL OF AGEING
(2021)
Article
Nutrition & Dietetics
Diana Tang, Yvonne Tran, Giriraj S. Shekhawat, George Burlutsky, Paul Mitchell, Bamini Gopinath
Summary: This study found that lower intake of fruit fiber and cereal fiber was associated with an increased risk of developing tinnitus. Dietary fiber, especially insoluble fiber, may reduce the risk of tinnitus by lowering vascular risk factors. Further longitudinal studies on different types and sources of fiber and tinnitus risk are needed to confirm these findings.
Article
Public, Environmental & Occupational Health
Ferran Espuny Pujol, Ruth Hancock, Marcello Morciano
Summary: The study found that mortality risks increased for care home residents aged 65+ over the past decade, while slightly decreasing for matched community-dwelling residents. The survival gap between older care home and community-dwelling residents has been widening, especially at younger ages. In the future, the extent to which the COVID-19 pandemic has further exacerbated this gap can be assessed.
SOCIAL SCIENCE & MEDICINE
(2021)