Article
Oncology
Qiang Hu, Weipu Mao, Tiange Wu, Zhipeng Xu, Junjie Yu, Can Wang, Saisai Chen, Shuqiu Chen, Bin Xu, Yueshuang Xu, Ming Chen
Summary: In RCC patients undergoing laparoscopic partial or radical nephrectomy, NLR and PLR were identified as biomarkers of systemic inflammation associated with increased risk of sarcopenia. The best cutoff points for predicting sarcopenia risk were NLR >2.88 and PLR >135.63, with higher levels indicating a greater risk. Adjusting for various variables, patients with NLR >2.88 and PLR >135.63 had significantly higher risks of developing sarcopenia compared to those with lower NLR or PLR levels.
FRONTIERS IN ONCOLOGY
(2021)
Review
Clinical Neurology
Mi Su, Xiaoxiao Ouyang, Yongyan Song
Summary: This meta-analysis supports the association between depression and inflammation, with NLR being a potential indicator of depression. However, no significant differences were found in PLR and MLR values between depressed subjects and controls. Further large-scale studies are needed to evaluate the role of PLR and MLR in depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Infectious Diseases
Christian Cosmus Enersen, Gertrud Baunbaek Egelund, Pelle Trier Petersen, Stine Andersen, Pernille Ravn, Gernot Rohde, Birgitte Lindegaard, Andreas Vestergaard Jensen
Summary: The ratios of neutrophil-to-lymphocyte (NLR), monocyte-to-lymphocyte (MLR), and platelet-to-lymphocyte (PLR) are potential biomarkers for predicting mortality in various diseases. This study aimed to investigate the association between NLR, MLR, PLR, and 90-day mortality in patients with community-acquired pneumonia (CAP), as well as the potential improvement of the prediction rule CURB-65 by adding these biomarkers. The results showed that NLR and PLR were associated with 90-day mortality in CAP, but adding them to CURB-65 did not improve its performance.
Article
Cardiac & Cardiovascular Systems
Martha Fors, Santiago Ballaz, Hegira Ramirez, Francisco X. Mora, Mary Pulgar-Sanchez, Kevin Chamorro, Esteban Fernandez-Moreira
Summary: Sex-dependent differences exist in the contribution of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and mean platelet volume-to-platelet ratio (MPR) to COVID-19 severity and mortality. The mortality rate of COVID-19 is higher among men, and men have higher levels of NLR, MLR, and MPR compared to women. NLR, MLR, and PLR have better sensitivity for predicting pneumonia severity in men, while their specificity is enhanced in women.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Health Care Sciences & Services
Georgios Tzikos, Ioannis Alexiou, Sokratis Tsagkaropoulos, Alexandra-Eleftheria Menni, Georgios Chatziantoniou, Soultana Doutsini, Theodosios Papavramidis, Vasilios Grosomanidis, George Stavrou, Katerina Kotzampassi
Summary: In this study, the researchers investigated whether NLR and PLR could predict mortality and length of hospital stay after cardiac surgery. The results showed that NLR and PLR are efficient predictive factors for 90-day mortality and length of stay in cardiac surgery patients. Monitoring NLR and PLR postoperatively could provide a reliable predictor of patients' outcomes.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Immunology
Qian Song, Song-Xiao Xu, Jun-Zhou Wu, Lin Ling, Sheng Wang, Xin-Hua Shu, Dan-Ni Ying, Wang-Wei Pei, Yu-Chen Wu, Su-Fang Sun, Yi-Ning Zhang, Si-Hang Zhou, Zhu-Yan Shao
Summary: This study analyzed data from 991 ovarian cancer patients and found that the lymphocyte to monocyte ratio (LMR) and platelet to neutrophil ratio (PNR) were independent prognostic indicators of ovarian cancer. In contrast, the platelet to lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) had limited prognostic value. In conclusion, LMR and PNR are superior prognostic indicators in ovarian cancer.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Urology & Nephrology
Yanping Zhang, Aihong Zhang, Lin Wei, Kaiming Ren, Qian Wang, Bing Shao, Chen Zhao, Zhuo Ren, Jiuxu Bai, Ning Cao
Summary: This study aimed to assess whether the platelet-to-lymphocyte ratio (PLR) is independently associated with all-cause mortality and cardiovascular mortality in maintenance hemodialysis (MHD) patients. The results showed that high PLR levels can independently predict all-cause and cardiovascular mortality in MHD patients.
Article
Immunology
Ebru Yuce
Summary: The role of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in predicting spontaneous preterm birth was investigated. Retrospective data collected from hospital records between February 2018 and November 2022 showed that NLR and PLR values can predict preterm birth with high sensitivity and specificity. Predicting preterm birth allows for sensitive and smooth management of the pregnancy process.
JOURNAL OF INFLAMMATION RESEARCH
(2023)
Article
Clinical Neurology
Yanyan Wei, Junhui Feng, Jinbao Ma, Dongning Chen, Jingxu Chen
Summary: This study examines the role of alterations in the immune-inflammation system in affective disorders, specifically major depressive disorder (MDD) and bipolar disorder (BD). The neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) are investigated as inflammation markers. The findings reveal elevated NLR and MLR in first-episode and recurrent MDD patients, as well as higher NLR and MLR and lower PLR in BD patients. Moreover, BD manic episode patients have significantly higher NLR and MLR compared to BD depressive episode patients or MDD patients. Overall, this study highlights the importance of systemic inflammation in the pathophysiology of MDD and BD, particularly during manic BD episodes.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Fanchao Meng, Xiuping Yan, Junhui Qi, Fan He
Summary: This study aimed to investigate the association and potential non-linear relationship between neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and monocyte to lymphocyte ratio (MLR) with depression. Based on a cross-sectional study of US adults, it was found that only PLR was significantly associated with depression. Furthermore, the relationships between NLR, PLR, and MLR with depression were found to be non-linear.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Pediatrics
Tan Xie, Dongliang Hou, Jiaxiang Wang, Song Zhao
Summary: This study showed that elevated NLR and PLR were poor prognostic factors in hepatoblastoma patients before treatment, and NLR was an independent prognostic factor for overall survival.
FRONTIERS IN PEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Peng Ning, Fan Yang, Jun Kang, Jing Yang, Jiaxing Zhang, Yi Tang, Yanghong Ou, Haiyan Wan, Hongyi Cao
Summary: This study found that platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-lymphocyte ratio (MLR) were associated with arterial stiffness in patients with diabetes. Among them, NLR showed higher accuracy in predicting arterial stiffness.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Oncology
Jiali Leng, Fei Wu, Lihui Zhang
Summary: This meta-analysis found that pretreatment neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) may serve as biomarkers for predicting poor prognosis in patients with endometrial cancer, while monocyte-lymphocyte ratio (MLR) is not associated with prognosis.
FRONTIERS IN ONCOLOGY
(2022)
Review
Psychiatry
Yanwei Cheng, Yiwen Wang, Xiangyi Wang, Zhuoya Jiang, Lijun Zhu, Shaokuan Fang
Summary: This study found that the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are significantly higher in patients with depression. However, the monocyte-to-lymphocyte ratio (MLR) is slightly higher but not significantly different. Sensitivity and subgroup analysis revealed differences in inflammatory ratios in different regions and in patients with post-stroke depression (PSD).
FRONTIERS IN PSYCHIATRY
(2022)
Article
Immunology
Wei Fu, Weixia Ye, Xianqiang Liu, Sirui Zhu, Hu Fu, Rui Zhu, Hongmin Li, Haoyun Zeng, Qin Wang
Summary: The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are valuable biomarkers for assessing the clinical significance of Henoch-Schonlein purpura (HSP) and its complications, with NLR particularly useful in predicting gastrointestinal complications and renal involvement in HSP patients. Further well-designed and large cohort studies are needed to confirm these findings.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Oncology
Emre Altintas, Mehmet Kaynar, Z. Esin Celik, Murat Celik, Ozcan Kilic, Murat Akand, Serdar Goktas
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2020)
Editorial Material
Urology & Nephrology
Murat Gul, Mehmet Kaynar
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
(2021)
Article
Urology & Nephrology
Murat Gul, Mehmet Kaynar, Mehmet Yildiz, Ali Furkan Batur, Murat Akand, Ozcan Kilic, Serdar Goktas
JOURNAL OF ENDOUROLOGY
(2020)
Article
Medicine, General & Internal
Ali Furkan Batur, Muhammed Furkan Aydogan, Ozcan Kilic, Muslu Kazim Korez, Murat Gul, Mehmet Kaynar, Serdar Goktas, Murat Akand
Summary: The study found a positive correlation between poor prognosis in patients with transitional cell bladder cancer and systemic inflammatory markers (NLR, LMR, PLR, and PMR), but not with DRR.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Medicine, General & Internal
Emre Altintas, Tuncer Bahceci, Ali Furkan Batur, Mehmet Kaynar, Ozcan Kilic, Murat Akand, Serdar Goktas, Murat Gul
Summary: The study aimed to assess the awareness of fluoroscopy use and preventive measures among urologists in Turkey. Results showed a lack of information on radiation protection and harmful effects of radiation among participants, indicating a need for systematic training programs on fluoroscopy use and radiation exposure in urology residency.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Urology & Nephrology
Mehmet Kaynar, Zeliha Esin Celik, Emre Altintas, Ali Furkan Batur, Ozcan Kilic, Murat Akand, Murat Gul, Serdar Goktas
Summary: This study found that there were no significant differences in perioperative parameters and histopathological analyses between patients undergoing bipolar transurethral bladder tumor resection with different bipolar devices. However, the ratio of obturator jerk was significantly higher in the Olympus TURis group compared to the Gyrus group.
UROLOGIA INTERNATIONALIS
(2021)
Article
Andrology
Murat Gul, Ali Furkan Batur, Kadir Bocu, Mehmet Kaynar, Ozcan Kilic, Serdar Goktas
Summary: This study found that the probability of detecting diabetes mellitus, hypertension, and coronary vascular disease in patients with severe erectile dysfunction (ED) was significantly higher than in those with mild/moderate ED, and more ED symptoms emerged in the winter season. There was no significant difference in seasonal variation between patients with bladder tumor and post-procedural ED.
Article
Radiology, Nuclear Medicine & Medical Imaging
Suleyman Bakdik, Necdet Poyraz, Teyfik Kucukkartallar, Pembe Oltulu
Summary: Hepatic pseudolymphoma is a rare condition that is usually asymptomatic and often detected incidentally. Imaging features resemble other hepatic nodular lesions, making accurate diagnosis challenging. Differentiating it from other malignant lymphomas is also difficult with biopsy.
CURRENT MEDICAL IMAGING
(2022)
Article
Urology & Nephrology
Ali Furkan Batur, Mustafa Gulmen, Kadir Bocu, Murat Gul, Mehmet Kaynar, Ozcan Kilic, Serdar Goktas
Summary: The number of kidney stone surgeries during the COVID-19 period decreased significantly, with more patients opting for retrograde intrarenal surgery. The pandemic led to a reduction in elective surgery cases, potentially increasing complications and delayed treatment, while also impacting resident surgical training due to fewer cases.
JOURNAL OF UROLOGICAL SURGERY
(2021)
Review
Urology & Nephrology
Mehmet Kaynar, Ana Luisa Quinta Gomes, Ioannis Sokolakis, Murat Guel
Summary: The COVID-19 pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 has a greater impact on men, leading to more severe disease and higher mortality rates. Androgens may play a role in the development of severe disease and erectile dysfunction. Endothelial dysfunction, direct testicular damage, and psychological burden are potential pathways for the development of erectile dysfunction in COVID-19.
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Seyma Babaoglu, Necdet Poyraz, Bugra Kaya, Siddika Findik, Sinan Demircioglu
MOLECULAR IMAGING AND RADIONUCLIDE THERAPY
(2022)
Article
Urology & Nephrology
Murat Gul, Mehmet Gokhan Culha, Kadir Bocu, Ali Furkan Batur, Emre Altintas, Mehmet Kaynar, Serdar Goktas, Ozcan Kilic
Summary: The study aimed to evaluate the validity and reliability of the Turkish version of the hallym post micturition dribble questionnaire (HPMDQ) and assess the effectiveness of bulbar urethral massage in patients with post-micturition dribble (PMD). The results showed that the Turkish version of HPMDQ is a reliable tool for evaluating patients with PMD and bulbar urethral massage is an effective method to relieve PMD.
JOURNAL OF UROLOGICAL SURGERY
(2022)
Article
Infectious Diseases
Gokcen Unal, Sevgi Pekcan, Ozge Metin Akcan, Sevgi Keles, Asli Imran Yilmaz, Fadime Ceyda Eldeniz, Hanife Tugce Caglar, Mehmet Ozdemir, Necdet Poyraz, Fahriye Kilinc, Ayse Bulut
Summary: This study aimed to evaluate the association between COVID-19, COVID-19-related drugs, TB reactivation, and TB incidence. By investigating eight patients diagnosed with TB during the early period of the pandemic, it was found that there was an increase in the incidence of TB in children and adolescents during this period. This may be related to the pathogenic structure of the COVID-19 virus with an unknown mechanism, as well as changes in lifestyle and healthcare policies during the pandemic. Further research is needed on this topic.
JOURNAL OF PEDIATRIC INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Pinar Diydem Yilmaz, Cengiz Kadiyoran, Suleyman Bakdik, Necdet Poyraz, Hulya Vatansev
ARCHIVES OF CLINICAL INFECTIOUS DISEASES
(2020)
Article
Medicine, General & Internal
Ali Furkan Batur, Mehmet Kaynar, Mehmet Yildiz, Ozcan Kilic, Serdar Goktas
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
(2020)
