Article
Veterinary Sciences
Carina de Castro Santos Melo, Angelina da Silva Freire, Marcela Aragao Galdeano, Camila Fraga da Costa, Anay Priscilla David de Oliveira Goncalves, Francesca Silva Dias, Daniel Ribeiro Menezes
Summary: In this study, fermented goat milk with probiotic potential was prepared for dogs in an in vitro model using 40 lactic acid bacteria isolates. The results showed that E. hirae isolates and fermented goat milk both demonstrated satisfactory probiotic efficiency and food safety for dogs in the in vitro setting. Evaluation included various analyses such as pH reduction, acidity increase, and higher levels of LAB in the fermented goat milk compared to the control group over a 36-day storage period.
RESEARCH IN VETERINARY SCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Muhammad Ishaq, Ashiq Khan, Ali Sher Bacha, Tariq Shah, Anum Hanif, Anum Ali Ahmad, Wencan Ke, Fuhou Li, Ahmad Ud Din, Zitong Ding, Xusheng Guo
Summary: The implementation of modern scientific protocols has improved the average human lifespan, but age-related challenges such as alterations in gut microbiota and functions, weakened immune responses, and increased oxidative stress still remain. Studies on the significance of gut microbiota dysbiosis and ageing, particularly the potential anti-ageing properties of certain Lactobacillus strains, are limited, highlighting the need for further research in this area.
Article
Food Science & Technology
Achirawit Ngamsomchat, Thida Kaewkod, Maytiya Konkit, Yingmanee Tragoolpua, Sakunnee Bovonsombut, Thararat Chitov
Summary: This study isolated and characterized probiotic bacteria from dairy and fermented foods, and used a selected strain to produce probiotic chevre cheese. The selected strain showed high tolerance to acid and bile salt, antibacterial activities against foodborne pathogens, and a high adhesion rate. The probiotic chevre cheese had a shelf life of 8 days and a sufficient level of probiotics.
Article
Nutrition & Dietetics
Dongting Yang, Wentao Lyu, Ziyi Hu, Jiting Gao, Zhiyao Zheng, Weijun Wang, Jenni Firrman, Daxi Ren
Summary: The study evaluated the probiotic effects of Lactobacillus fermentum ZJUIDS06 and Lactobacillus plantarum ZY08 on hyperlipidemic golden hamsters, demonstrating that Lactobacillus fermentum ZJUIDS06 increased colon SCFA levels, reduced serum LDL, total cholesterol, and triglycerides, and altered the cecum microbiota. Particularly, Lactobacillus fermentum ZJUIDS06 increased the abundance of Parabacteroides, indicating its potential in lowering cholesterol levels.
FRONTIERS IN NUTRITION
(2021)
Article
Microbiology
Donatella Scarafile, Diana Luise, Vincenzo Motta, Caterina Spiezio, Monica Modesto, Marzia Mattia Porcu, Yadid Yitzhak, Federico Correa, Camillo Sandri, Paolo Trevisi, Paola Mattarelli
Summary: Intestinal bacteria establish a host-specific relationship with the Red River Hog, resulting in a unique gut microbiota composition. This study analyzed the gut microbiota and Bifidobacterium species distribution in Red River Hogs housed in different zoological gardens to understand the effects of captivity and host genetics. The results showed that the gut microbiota reflects the lifestyle and age, while host genetics determine the Bifidobacterium population.
Article
Biochemistry & Molecular Biology
Ruth B. Cuvas-Limon, Pedro Ferreira-Santos, Mario Cruz, Jose Antonio Teixeira, Ruth Belmares, Clarisse Nobre
Summary: In this study, a novel functional beverage was developed by fermenting and extracting Aloe vera, combining the health benefits of probiotics, prebiotics, SCFA, and phenolic compounds. The produced Aloe vera juice showed great potential as a functional beverage with improved antioxidant activity.
Article
Immunology
Longxian Lv, Deguang Mu, Yiling Du, Ren Yan, Huiyong Jiang
Summary: CBLEB treatment alleviates cyclophosphamide-induced immunosuppression and dysbiosis of gut microbiota, corrects alterations in metabolome profiles, and induces recovery of altered carbohydrate metabolism and signal transduction pathways. The study provides a basis for utilizing CBLEB in the treatment of immunodeficiency.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Veterinary Sciences
Inhwan You, Feriel Yasmine Mahiddine, Heekee Park, Min Jung Kim
Summary: This study aimed to develop novel probiotics for dogs. By administering Lactobacillus acidophilus strains to dogs and analyzing oral samples, it was found that one strain significantly reduced a key factor in periodontitis without causing adverse effects on blood and reproductive ability.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Microbiology
Xuan Zou, Lei Pan, Min Xu, Xiaoqing Wang, Qi Wang, Ye Han
Summary: A study evaluated the probiotic properties of Lactobacillus sakei L-7 and found it had strong adhesion ability and high viability in the gastrointestinal tract. Feeding L. sakei L-7 to mice increased the richness of gut microbiota, abundance of beneficial bacteria, and levels of beneficial metabolites, while decreasing levels of harmful metabolites and inflammatory cytokines. These findings suggest that L. sakei L-7 may promote gut health and have the potential to be used as a probiotic.
MICROBIOLOGICAL RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Nabendu Debnath, Pooja Yadav, Ashok Kumar Yadav
Summary: This study isolated and characterized probiotic Lactobacilli from human fecal samples and evaluated their antioxidative properties. The findings showed that some Lactobacillus strains had the ability to withstand different environmental conditions and exhibited good antioxidant activity. These strains could potentially be used in functional foods to reduce oxidative stress.
INDIAN JOURNAL OF MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Feiyan Zhao, Xiaoye Bai, Juntao Zhang, Lai-Yu Kwok, Lingling Shen, Hao Jin, Tiansong Sun, Zhihong Sun, Heping Zhang
Summary: Bifidobacteria are beneficial gut inhabitants and their responses to probiotic intervention vary depending on subjects' geographic origins.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Nutrition & Dietetics
Huifang Li, Jing Wang, Yifan Fu, Ke Zhu, Zhiling Dong, Jinjun Shan, Liuqing Di, Shu Jiang, Tianjie Yuan
Summary: Glycyrrhizinic acid (GL) is used clinically to treat liver injury, and its bioavailability is closely linked to gut microbiota. Probiotic supplementation with L. rhamnosus R0011 can significantly enhance the bioavailability of GL in rats with liver injury by improving gut microbial composition and metabolic function.
Article
Environmental Sciences
Chenyan Hu, Zileng Huang, Mengyuan Liu, Baili Sun, Lizhu Tang, Lianguo Chen
Summary: This study highlights the impact of PFBS pollutant and probiotic L. rhamnosus on fish skin microbiota and immunity. PFBS exposure disrupts the skin microbiome and promotes mucus production, while probiotic supplement mitigates these effects and boosts immune functions.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Biotechnology & Applied Microbiology
Alexander Suvorov, Shuangzhi Zhao, Galina Leontieva, Galina Alekhina, Jinyu Yang, Anna Tsapieva, Alena Karaseva, Valentina Smelova, Danyang Guo, Leilei Chen
Summary: This study compared the probiotic effect of enterococcal Enterococcus faecium L3 to the antibiotic enramycin as a chicken feed additive. The results showed that chickens fed with the probiotic had greater weight gain, increased HDL levels in blood serum, and a different caecal microbiome composition compared to the control group. This suggests that probiotic E. faecium L3 could be a potential replacement for the antibiotic enramycin.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Chemistry, Multidisciplinary
Meena Kumari Palani Kumar, Prakash Motiram Halami, Muthukumar Serva Peddha
Summary: The probiotic strain Lactobacillus fermentum MCC2760 has shown beneficial effects in high-cholesterol diet-fed mice, including reducing serum lipids, anti-inflammatory properties, and improving gut barrier function. These findings highlight the potential of probiotic supplementation in managing hypercholesterolemia.
Article
Biotechnology & Applied Microbiology
Raphael S. Steinberg, Lilian C. Silva e Silva, Marcelo R. de Souza, Ronaldo B. Reis, Adriano F. Bicalho, Joao P. S. Nunes, Adriana A. M. Dias, Jacques R. Nicoli, Elisabeth Neumann, Alvaro C. Nunes
Summary: This study successfully isolated lactic bacteria with potential for combating mastitis, showing strong antagonism against mastitis pathogens and the ability to produce H2O2. These findings contribute to the future development of new tools for the prevention and treatment of bovine mastitis.
INTERNATIONAL MICROBIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Joana O. P. A. Coutinho, Monica F. Quintanilha, Marina R. A. Campos, Enio Ferreira, Graciele C. A. de Menezes, Luiz H. Rosa, Carlos A. Rosa, Katia D. Vital, Simone O. A. Fernandes, Valbert N. Cardoso, Jacques R. Nicoli, Fabiana C. P. Tiago, Flaviano S. Martins
Summary: Mucositis, a severe side effect of chemotherapy drugs in cancer treatment, has no effective treatment currently. This study showed that oral administration of the Antarctic strain of Rhodotorula mucilaginosa UFMGCB 18,377 could effectively reduce mucositis induced by 5-FU.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2022)
Article
Biotechnology & Applied Microbiology
Spencer S. Santos, Vivian C. Miranda, Luisa M. Trindade, Valbert N. Cardoso, Diego C. Reis, Geovanni D. Cassali, Jacques R. Nicoli, Denise C. Cara, Flaviano S. Martins
Summary: This study evaluated the probiotic effect of Bifidobacterium longum subsp. longum 5(1A) in a murine model of food allergy. The results showed that oral administration of this probiotic prevented weight loss, reduced immune reactions, and improved intestinal permeability. The dose of 10^8 CFU showed the best protective effect, and the use of live bacteria was necessary to achieve these beneficial effects.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Food Science & Technology
Karen Costa, Luana S. Silva, Cintia N. Kobori, Andreia M. da Silva, Jacques R. Nicoli
Summary: The study showed that microencapsulation techniques can effectively improve the survival rate of probiotics, especially when incorporated into plant pulp powder. Acerola pulp matrix can be used as an alternative vehicle for probiotic administration, maintaining efficacy even when stored at room temperature.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Medicine, Research & Experimental
Monica F. Quintanilha, Vivian C. Miranda, Ramon O. Souza, Bruno Gallotti, Clenio Cruz, Elandia A. Santos, Jacqueline Alvarez-Leite, Luis C. L. Jesus, Vasco Azevedo, Luisa M. Trindade, Valbert N. Cardoso, Enio Ferreira, Barbara A. Carvalho, Pedro M. G. Soares, Angelica T. Vieira, Jacques R. Nicoli, Flaviano S. Martins
Summary: This study demonstrates that Bifidobacterium longum 5(1A), a probiotic, has a protective effect against intestinal damage caused by irinotecan, suggesting its potential use as a probiotic therapy for mucositis.
Article
Biotechnology & Applied Microbiology
Quesia S. Damaceno, Bruno Gallotti, Isabela M. M. Reis, Yasmim C. P. Totte, Gabriella B. Assis, Henrique C. Figueiredo, Tales F. Silva, Vasco Azevedo, Jacques R. Nicoli, Flaviano S. Martins
Summary: Breast milk contains beneficial bacteria that can positively influence the health of newborns. The study identified 77 bacteria belonging to four genera, including Staphylococcus, Streptococcus, Leuconostoc, and Lacticaseibacillus. Two potential probiotics, Lacticaseibacillus rhamnosus and Leuconostoc mesenteroides, were selected and found to colonize the gastrointestinal tract in germ-free mice and maintain viability after spray-drying.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Correction
Multidisciplinary Sciences
Flaviano S. Martins, Guillaume Dalmasso, Rosa M. E. Arantes, Anne Doye, Emmanuel Lemichez, Patricia Lagadec, Veronique Imbert, Jean-Francois Peyron, Patrick Rampal, Jacques R. Nicoli, Dorota Czerucka
Article
Public, Environmental & Occupational Health
Gabriela de Melo Franco, Anderson Santos da Rocha, Laura Jorge Cox, Danielle Soares de Oliveira Daian e Silva, Debora Marques da Silveira e Santos, Marina Lobato Martins, Luis Claudio Romanelli, Ricardo Ishak, Antonio C. R. Vallinoto, Maria Rosa Q. Bomfim, Adele Caterino-de-Araujo, Jordana G. A. Coelho-dos-Reis, Flavio Guimaraes da Fonseca, Edel Figueiredo Barbosa-Stancioli
Summary: A multi-epitope protein was developed for the serological screening of HTLV-1/2 infection. The test showed high specificity and sensitivity in Brazilian samples, demonstrating its potential for accurate detection of HTLV-1/2 infection. This study is important for supporting public policies to reduce HTLV-1/2 transmission in Brazil.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Biotechnology & Applied Microbiology
Andressa Coelho Ferreira, Maria Rosa Quaresma Bomfim, Carlos Henrique de Barros da Costa Sobrinho, Daniela Talissa Lobo Boaz, Railane Da Silva Lira, Valeria Costa Fontes, Mariana Oliveira Arruda, Patricia Maria Wiziack Zago, Carlos Alberto Alves Dias Filho, Carlos Jose Moraes Dias, Marilene Oliveira da Rocha Borges, Rachel Melo Ribeiro, Cicero Wellington Brito Bezerra, Rosiane Silva Penha
Summary: This study aims to produce, characterize, and assess the antimicrobial activity and cytotoxicity of polymer blends based on chitosan and fish collagen. The results showed that these polymer blends have good biocompatibility and antimicrobial activity, making them suitable for biomedical applications.
Article
Biotechnology & Applied Microbiology
Vivian C. Miranda, Ramon O. Souza, Monica F. Quintanilha, Bruno Gallotti, Helder C. Assis, Ana Maria C. Faria, Jacques R. Nicoli, Denise C. Cara, Flaviano S. Martins
Summary: This study aimed to evaluate the probiotic and postbiotic potential of Akkermansia muciniphila BAA-835 in an ovalbumin food allergy model. The results showed that treatment with viable A. muciniphila could alleviate weight loss, decrease serum levels of allergy-related antibodies, reduce intestinal injury and inflammation, and modify the gut microbiota composition. Additionally, the administration of inactivated bacteria also had a postbiotic effect by reducing allergy-related immune responses. These findings suggest that A. muciniphila BAA-835 has both probiotic and postbiotic properties in the prevention and treatment of food allergies.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Medicine, Research & Experimental
Daniel Wagner de Castro Lima Santos, Yankee Costa Magalhaes Diniz, Raimunda Ribeiro da Silva, Sirlei Garcia Marques, Maria Rosa Quaresma Bomfim, Conceicao de Maria Pedrozo e Silva de Azevedo
Summary: This article presents a case of extensive human cutaneous protothecosis in northeastern Brazil. The diagnosis was based on histopathological examination and culturing of skin samples, followed by identification using mass spectrometry. Treatment with itraconazole was unsuccessful, but liposomal amphotericin followed by voriconazole led to clinical cure. Protothecosis should be considered as a diagnostic possibility in cases with skin lesions after trauma, especially when the evolution is atypical.
MEDICAL MYCOLOGY CASE REPORTS
(2023)
Article
Microbiology
Artur Serra Neto, Sirlei G. Marques, Maria Rosa Q. Bomfim, Silvio G. Monteiro, Rosangela C. de Souza, Rodolfo A. Nunes
Summary: Hand antisepsis of medical personnel is crucial in patient care as it prevents the spread of pathogenic microorganisms during surgical procedures. This study examined the prevalence of microorganisms on the hands of 131 surgeons before surgery in a university hospital. The results showed a high frequency of microorganisms before handwashing, but after surgical antisepsis, the rate dropped significantly. Gram-positive species, particularly Staphylococcus spp. and Micrococcus luteus, were the most detected, followed by gram-negative species such as Stenotrophomonas maltophilia and Acinetobacter baumanii.
Article
Biotechnology & Applied Microbiology
Diego Lisboa Rios, Patricia Costa Lima da Silva, Cesar Silva Santana Moura, Camila Nair Batista Couto Villanoeva, Gabriel da Rocha Fernandes, Ana Agustina Bengoa, Graciela Liliana Garrote, Analia Graciela Abraham, Jacques Robert Nicoli, Elisabeth Neumann, alvaro Cantini Nunes
Summary: This study compared the bacterial and fungal diversity of kefir beverages produced using milk or sugared water as propagation matrices. The results showed that milk and water kefir have different microbial communities, but share similar main functional processes with slight quantitative variations.
INTERNATIONAL MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Raphael S. Steinberg, Lilian C. Silva e Silva, Marcelo R. de Souza, Ronaldo B. Reis, Patricia C. L. da Silva, Gustavo A. Lacorte, Jacques R. Nicoli, Elisabeth Neumann, Alvaro C. Nunes
Summary: This study explored the bacterial diversity in raw milk samples from dairy cows using 16S rRNA amplicon sequencing. The milk bacterial microbiome was found to be dominated by Firmicutes, Proteobacteria, and Actinobacteria, with significant differences in composition related to udder health status and breed.
INTERNATIONAL MICROBIOLOGY
(2022)