Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease

Platelet protein shake as playmaker

(2012) P. E. van der Meijden et al.   BLOOD

Does a Pro-Inflammatory Process Precede Alzheimers Disease and Mild Cognitive Impairment?

(2012) M. T. Ferretti et al.   Current Alzheimer Research

Platelet mRNA

(2012) Jesse W. Rowley et al.   CURRENT OPINION IN HEMATOLOGY

Human neutrophil alpha-defensins induce formation of fibrinogen and thrombospondin-1 amyloid-like structures and activate platelets via glycoprotein IIb/IIIa

(2012) M. HORN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A large scale multivariate parallel ICA method reveals novel imaging–genetic relationships for Alzheimer's disease in the ADNI cohort

(2012) Shashwath A. Meda et al.   NEUROIMAGE

Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease

(2012) Laura E. Donovan et al.   Proteomics Clinical Applications

Alteration of the platelet transcriptome in chronic kidney disease

(2012) Hélène Plé et al.   THROMBOSIS AND HAEMOSTASIS

Ca2+ dysfunction in neurodegenerative disorders: Alzheimer's disease

(2011) Laura Fedrizzi et al.   BIOFACTORS

Association of Metabolic Dysregulation With Volumetric Brain Magnetic Resonance Imaging and Cognitive Markers of Subclinical Brain Aging in Middle-Aged Adults

(2011) Zaldy S. Tan et al.   DIABETES CARE

Polyubiquitin Linkage Profiles in Three Models of Proteolytic Stress Suggest the Etiology of Alzheimer Disease

(2011) Eric B. Dammer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease

(2011) Marcus O. W. Grimm et al.   JOURNAL OF NEUROCHEMISTRY

Coated-platelet levels and progression from mild cognitive impairment to Alzheimer disease

(2011) C. I. Prodan et al.   NEUROLOGY

Low-density platelet populations demonstrate lowin vivoactivity in sporadic Alzheimer disease

(2011) P. Järemo et al.   PLATELETS

Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis

(2011) Rebecca Craig-Schapiro et al.   PLoS One

Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease

(2011) Madhav Thambisetty et al.   PLoS One

Functional Links Between A  Toxicity, Endocytic Trafficking, and Alzheimer's Disease Risk Factors in Yeast

(2011) S. Treusch et al.   SCIENCE

A Role for Myosin VI in the Localization of Axonal Proteins

(2011) Tommy L. Lewis et al.   PLOS BIOLOGY

Blood-based biomarkers of Alzheimer’s disease: challenging but feasible

(2010) Madhav Thambisetty et al.   Biomarkers in Medicine

Thrombospondin-1 induces platelet activation through CD36-dependent inhibition of the cAMP/protein kinase A signaling cascade

(2010) W. Roberts et al.   BLOOD

Rho Kinase II Phosphorylation of the Lipoprotein Receptor LR11/SORLA Alters Amyloid-β Production

(2010) Jeremy H. Herskowitz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predictive Value of Platelet Activation for the Rate of Cognitive Decline in Alzheimer's Disease Patients

(2010) Konstantinos Stellos et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

(2010) S. W. Pimplikar et al.   JOURNAL OF NEUROSCIENCE

Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease

(2010) Marta Cortes-Canteli et al.   NEURON

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Contribution of Vascular Risk Factors to the Progression in Alzheimer Disease

(2009) Elizabeth P. Helzner et al.   ARCHIVES OF NEUROLOGY

Platelet membrane proteomics: a novel repository for functional research

(2009) U. Lewandrowski et al.   BLOOD

The Role of IGF-1 Receptor and Insulin Receptor Signaling for the Pathogenesis of Alzheimers Disease: From Model Organisms to Human Disease

(2009) S. Freude et al.   Current Alzheimer Research

Systematical Optimization of Reverse-Phase Chromatography for Shotgun Proteomics

(2009) Ping Xu et al.   JOURNAL OF PROTEOME RESEARCH

Investigating GABA and its function in platelets as compared to neurons

(2009) Fatima Shad Kaneez et al.   PLATELETS

Proteomic and Phospho-Proteomic Profile of Human Platelets in Basal, Resting State: Insights into Integrin Signaling

(2009) Amir H. Qureshi et al.   PLoS One

CSF Multianalyte Profile Distinguishes Alzheimer and Parkinson Diseases

(2008) Jing Zhang et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Systematic Approach for Validating the Ubiquitinated Proteome

(2008) Nicholas T. Seyfried et al.   ANALYTICAL CHEMISTRY

Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: A membrane proteomics approach

(2008) Nicholas T. Seyfried et al.   CANCER LETTERS

Rate of MMSE score change in Alzheimer's disease: Influence of education and vascular risk factors

(2008) Francesco Roselli et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Plasma Gelsolin: Function, Prognostic Value, and Potential Therapeutic Use

(2008) Robert Bucki et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain

(2008) Jae K. Ryu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling

(2007) J. S. Isenberg et al.   BLOOD

Association of platelet-derived soluble glycoprotein VI in plasma with Alzheimer’s disease

(2007) Christoph Laske et al.   JOURNAL OF PSYCHIATRIC RESEARCH