Plasma amyloid beta measurements - a desired but elusive Alzheimer's disease biomarker

CSF biomarkers cutoffs: the importance of coincident neuropathological diseases

(2012) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

Improved protocol for measurement of plasma β-amyloid in longitudinal evaluation of Alzheimer’s Disease Neuroimaging Initiative study patients

(2012) Michal J. Figurski et al.   Alzheimers & Dementia

β-Amyloid Dynamics in Human Plasma

(2012) Yafei Huang et al.   ARCHIVES OF NEUROLOGY

Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study of the Oral γ-Secretase Inhibitor BMS-708163 (Avagacestat): Tolerability Profile, Pharmacokinetic Parameters, and Pharmacodynamic Markers

(2012) Gary Tong et al.   CLINICAL THERAPEUTICS

Stability of amyloid-β peptides in plasma and serum

(2012) Mirko Bibl et al.   ELECTROPHORESIS

Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2

(2012) Carla A. Ibrahim-Verbaas et al.   HUMAN GENETICS

Midlife Blood Pressure, Plasma β-Amyloid, and the Risk for Alzheimer Disease

(2012) Nilay S. Shah et al.   HYPERTENSION

Interplay between α-, β-, and γ-Secretases Determines Biphasic Amyloid-β Protein Level in the Presence of a γ-Secretase Inhibitor

(2012) Fernando Ortega et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Longitudinal plasma amyloid beta as a biomarker of Alzheimer’s disease

(2012) Robert A. Rissman et al.   JOURNAL OF NEURAL TRANSMISSION

Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography

(2012) David A Wolk et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

(2012) Eric M Reiman et al.   LANCET NEUROLOGY

Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI

(2011) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Transforming cerebrospinal fluid Aβ42 measures into calculated Pittsburgh compound B units of brain Aβ amyloid

(2011) Stephen D. Weigand et al.   Alzheimers & Dementia

Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative

(2011) Hugo Vanderstichele et al.   Alzheimers & Dementia

Comparison of Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of the Amyloid β Monoclonal Antibody Solanezumab in Japanese and White Patients With Mild to Moderate Alzheimer Disease

(2011) Kazunori Uenaka et al.   CLINICAL NEUROPHARMACOLOGY

Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?

(2011) Bruno P Imbimbo et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Association of Plasma β-Amyloid Level and Cognitive Reserve With Subsequent Cognitive Decline

(2011) Kristine Yaffe   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

(2011) Christopher M. Clark   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

γ-Secretase modulators do not induce Aβ-rebound and accumulation of β-C-terminal fragment

(2011) Ting Li et al.   JOURNAL OF NEUROCHEMISTRY

Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome

(2011) Antonia M.W. Coppus et al.   NEUROBIOLOGY OF AGING

Plasma A  and PET PiB binding are inversely related in mild cognitive impairment

(2011) D. P. Devanand et al.   NEUROLOGY

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

The Relationship of Plasma Aβ Levels to Dementia in Aging Individuals With Down Syndrome

(2010) Yasuji Matsuoka et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Plasma Amyloid Beta-42 Independently Predicts Both Late-Onset Depression and Alzheimer Disease

(2010) Imrich Blasko et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Plasma β-Amyloid and Cognitive Decline

(2010) Stephanie A. Cosentino et al.   ARCHIVES OF NEUROLOGY

Change in plasma A  peptides and onset of dementia in adults with Down syndrome

(2010) N. Schupf et al.   NEUROLOGY

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Ten-Year Change in Plasma Amyloid β Levels and Late-Life Cognitive Decline

(2009) Olivia I. Okereke et al.   ARCHIVES OF NEUROLOGY

Cerebrospinal fluid tau and ptau181increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease

(2009) Anne M. Fagan et al.   EMBO Molecular Medicine

Amyloid β peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing

(2009) P. Lewczuk et al.   EXPERIMENTAL NEUROLOGY

Plasmaβ-amyloid and duration of Alzheimer's disease in adults with Down syndrome

(2009) V. P. Prasher et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

No correlation between time-linked plasma and CSF Aβ levels

(2009) Nathalie Le Bastard et al.   NEUROCHEMISTRY INTERNATIONAL

Association of plasma amyloid   with risk of dementia: The prospective Three-City Study

(2009) J. -C. Lambert et al.   NEUROLOGY

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

(2008) Alex E. Roher et al.   Alzheimers & Dementia

Plasma Amyloid β-Protein and C-reactive Protein in Relation to the Rate of Progression of Alzheimer Disease

(2008) Joseph J. Locascio et al.   ARCHIVES OF NEUROLOGY

Plasma β Amyloid and the Risk of Alzheimer Disease and Dementia in Elderly Men

(2008) Johan Sundelöf et al.   ARCHIVES OF NEUROLOGY

Evaluation of plasma Aβ40 and Aβ42 as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment

(2008) Oskar Hansson et al.   NEUROBIOLOGY OF AGING

Plasma amyloid levels and the risk of AD in normal subjects in the Cardiovascular Health Study

(2008) O. L. Lopez et al.   NEUROLOGY

Peripheral A  subspecies as risk biomarkers of Alzheimer's disease

(2008) N. Schupf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma amyloid   protein is elevated in late-onset Alzheimer disease families

(2007) N. Ertekin-Taner et al.   NEUROLOGY