Mussel-Glue Derived Peptide-Polymer Conjugates to Realize Enzyme-Activated Antifouling Coatings

Enzyme-activated polymer coatings based on peptide-polymer conjugates are described. Tyrosinase is used to switch on adhesive functions of a mussel-glue derived peptide segment, leading to bioconjugates that adhere to steel. The coating resists seawater treatments and modulates surface properties to antifouling surfaces by strongly reducing protein adsorption.