Article
Clinical Neurology
Xin Feng, Xin Tong, Fei Peng, Hao Niu, Peng Qi, Jun Lu, Yang Zhao, Weitao Jin, Zhongxue Wu, He Liu, Yuanli Zhao, Aihua Liu, Daming Wang
Summary: The number of coexisting intracranial aneurysms does not increase the risk of rupture for individual aneurysms, but it may increase the risk of SAH in patients with multiple aneurysms, highlighting the significant additive effect on SAH risk.
Article
Clinical Neurology
Marvin Darkwah Oppong, Lasse Lohrer, Karsten H. Wrede, Mehdi Chihi, Alejandro N. Santos, Philipp Dammann, Anna Michel, Laurel Rauschenbach, Maryam Said, Yan Li, Benedikt Frank, Ulrich Sure, Ramazan Jabbarli
Summary: This study aimed to identify the risk factors leading to post-SAH epilepsy. It found that thyroid dysfunction, decompressive craniectomy and shunt placement, prolonged tachycardia, as well as anemia signs were independently associated with symptomatic epilepsy after aSAH.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2023)
Article
Clinical Neurology
Junlin Lu, Mingtao Li, Jan-Karl Burkhardt, Yuanli Zhao, Youxiang Li, Xiaolin Chen, Yang Zhao, Jizong Zhao
Summary: This study found that unruptured giant intracranial aneurysms require treatment due to their high rupture rate and mortality. Older age, posterior circulation location, and larger size are risk factors for poor prognosis. Both surgical (ST) and endovascular (ET) treatments showed lower mortality rates than conservative treatment (CT), with ET having a higher recurrence rate and lower complication rate than ST.
TRANSLATIONAL STROKE RESEARCH
(2021)
Article
Clinical Neurology
Luigi Rigante, Hieronymus D. Boogaarts, Ronald H. M. A. Bartels, Priya Vart, Rene Aquarius, J. Andre Grotenhuis, Walid Moudrous, Anthonius M. De Korte, Joost de Vries
Summary: The incidence of subsequent aSAHs is high in patients with aSAH-MIA, with untreated mirror and de novo aneurysms associated with higher rupture risk. Longer follow-up and prophylactic treatment of asymptomatic aneurysms at higher rupture risk are recommended to prevent the significant poor outcome of subsequent aSAHs.
WORLD NEUROSURGERY
(2021)
Article
Neuroimaging
Mathilde Aubertin, Clement Jourdaine, Cedric Thepenier, Marc-Antoine Labeyrie, Vittorio Civelli, Jean-Pierre Saint-Maurice, Alexis Guedon, Emmanuel Houdart
Summary: The study found that for unruptured intracranial aneurysms in Western populations, follow-up results showed that aneurysms with stable morphology can be managed conservatively, while those with unstable morphology require treatment. The study revealed a low risk of rupture and mortality unrelated to aneurysms.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
Rob Molenberg, Marlien W. Aalbers, Aryan Mazuri, Gert Jan Luijckx, Jan D. M. Metzemaekers, Rob J. M. Groen, Maarten Uyttenboogaart, J. Marc C. van Dijk
Summary: This study evaluated the validity of the UIATS model in predicting aneurysm growth or rupture in patients with unruptured intracranial aneurysms. The results showed poor performance of the UIATS model in predicting aneurysm progression during follow-up.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Review
Clinical Neurology
Dingke Wen, Yuqi Chen, Wei Zhu, Zongjun Peng, Lu Ma
Summary: A meta-analysis was conducted to evaluate the risk of hemorrhage and rupture in ischemic stroke patients with concomitant unruptured aneurysm. The results showed that the rate of intracranial hemorrhage related to unruptured aneurysms was low, and the risk of rupture was relatively small compared to stroke patients without aneurysms.
JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Karl R. Abi-Aad, Rudy J. Rahme, Arjun Syal, Nicole M. De La Pena, Evelyn L. Turcotte, Devi P. Patra, Breck Jones, Brian Chong, Chandan Krishna, Bernard R. Bendok
Summary: In this study, data from 600 patients enrolled in the HEAT trial were analyzed to develop and validate a model for predicting the risk of aneurysmal hemorrhage. Factors such as dome-to-neck ratio, shape, and aneurysm location were found to be associated with an increased risk of hemorrhage.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Caleb Rutledge, Daniel M. S. Raper, Soren Jonzzon, Kunal P. Raygor, Matheus Prado Pereira, Ethan A. Winkler, Li Zhang, Michael T. Lawton, Adib A. Abla
Summary: Elderly patients over the age of 65 have significantly worse outcomes after subarachnoid hemorrhage. The sensitivity of the UIATS model for detecting those at risk of SAH is significantly lower in elderly patients, potentially leading to undertreatment of elderly patients.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Silvia Hernandez-Duran, Dorothee Mielke, Veit Rohde, Vesna Malinova
Summary: The study retrospectively analyzed ruptured intracranial aneurysms to evaluate the sensitivity of the unruptured intracranial aneurysm treatment score (UIATS) in detecting aneurysms at risk of rupture. The UIATS showed a low sensitivity of 44% for detecting aneurysms at risk of rupture.
NEUROSURGICAL REVIEW
(2021)
Article
Clinical Neurology
James Feghali, Abhishek Gami, Risheng Xu, Christopher M. Jackson, Rafael J. Tamargo, Cameron G. McDougall, Judy Huang, Justin M. Caplan
Summary: The current predictive scoring systems for unruptured aneurysms may underestimate future rupture risk, leading to overly conservative management strategies in some patients. Patients recommended for conservative therapy were more likely to experience complications and have a worse prognosis after rupture.
NEUROSURGICAL REVIEW
(2021)
Article
Medicine, General & Internal
Seppo Juvela
Summary: The study found that patients with moderate or severe disability after SAH had a lower risk of rupture of UIAs compared to those with good recovery or minimal disability, potentially due to age differences.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
Sen Wei, Yin Yuan, Dongdong Li, Xinbin Guo, Sheng Guan, Yuming Xu
Summary: This study retrospectively reviewed patients with intracranial aneurysms and subarachnoid hemorrhage and found an association between homocysteine levels and aneurysm rupture.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Alis J. Dicpinigaitis, Syed Faraz Kazim, Fawaz Al-Mufti, Daniel E. Hall, Katherine E. Reitz, Kavelin Rumalla, Matthew K. McIntyre, Adam S. Arthur, Visish M. Srinivasan, Jan-Karl Burkhardt, Meic H. Schmidt, Chirag D. Gandhi, Christian A. Bowers
Summary: This study evaluated frailty in aneurysmal subarachnoid hemorrhage (aSAH) using large-scale data and compared the effectiveness of the risk analysis index (RAI), modified frailty index (mFI), and Hospital Frailty Risk Score (HFRS). The RAI showed the largest effect size and discriminative ability in predicting poor functional outcomes in aSAH patients.
JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Julius Dengler, Daniel Ruefenacht, Bernhard Meyer, Veit Rohde, Matthias Endres, Pavlina Lenga, Konstantin Uttinger, Viktoria Ruecker, Maria Wostrack, Adisa Kursumovic, Bujung Hong, Dorothee Mielke, Nils Ole Schmidt, Jan-Karl Burkhardt, Philippe Bijlenga, Edoardo Boccardi, Christophe Cognard, Peter U. Heuschmann, Peter Vajkoczy
Summary: Limited clinical evidence exists on giant intracranial aneurysms (GIAs), with a focus on their natural history, case fatality, and treatment outcomes for both ruptured and unruptured cases. Both ruptured and unruptured GIAs displayed poor prognosis, with high rupture rates in the unruptured cases. Patients undergoing surgical or endovascular treatment had lower case fatality and rupture rates compared to those receiving conservative management, likely due to differences in patient selection criteria.
JOURNAL OF NEUROSURGERY
(2021)
Article
Rehabilitation
Takeshi Imura, Yuki Nagasawa, Tetsuji Inagawa, Naoki Imada, Hiroaki Izumi, Katsuya Emoto, Itaru Tani, Hiroyuki Yamasaki, Yuichiro Ota, Shuichi Oki, Tadanori Maeda, Osamu Araki
JOURNAL OF PHYSICAL THERAPY SCIENCE
(2015)
Article
Clinical Neurology
Tetsuji Inagawa
WORLD NEUROSURGERY
(2016)
Article
Clinical Neurology
Tetsuji Inagawa, Masaaki Shibukawa, Toshikazu Hidaka
WORLD NEUROSURGERY
(2018)
Article
Clinical Neurology
Tetsuji Inagawa, Kaita Yahara, Naohiko Ohbayashi
NEUROLOGIA MEDICO-CHIRURGICA
(2014)
Article
Neurosciences
Yuji Iwamoto, Takeshi Imura, Takahiro Suzukawa, Hiroki Fukuyama, Takayuki Ishii, Shingo Taki, Naoki Imada, Masaaki Shibukawa, Tetsuji Inagawa, Hayato Araki, Osamu Araki
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2019)
Article
Neurosciences
Yuji Iwamoto, Takeshi Imura, Ryo Tanaka, Naoki Imada, Tetsuji Inagawa, Hayato Araki, Osamu Araki
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2020)
Article
Neurosciences
Takeshi Imura, Yuji Iwamoto, Tetsuji Inagawa, Naoki Imada, Ryo Tanaka, Haruki Toda, Yu Inoue, Hayato Araki, Osamu Araki
Summary: The study used machine learning methods to identify factors affecting home discharge for stroke patients, including functional and environmental factors. It found that factors such as house renovation and upper body dressing ability have a positive impact on home discharge.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2021)
Article
Neurosciences
Takeshi Imura, Yuji Iwamoto, Yuki Azuma, Tetsuji Inagawa, Naoki Imada, Ryo Tanaka, Hayato Araki, Osamu Araki
Summary: This study utilized machine learning technology to identify influential factors affecting home discharge in stroke patients who use a wheelchair after discharge, highlighting the significant impact of environmental factors on discharge to home.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2021)
Article
Neurosciences
Takeshi Imura, Haruki Toda, Yuji Iwamoto, Tetsuji Inagawa, Naoki Imada, Ryo Tanaka, Yu Inoue, Hayato Araki, Osamu Araki
Summary: This study evaluated five supervised machine learning algorithms for classifying the possibility of home discharge in stroke patients, with k-NN and SVM models showing the best performance.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2021)
Article
Rehabilitation
Yuji Iwamoto, Ryo Tanaka, Takeshi Imura, Tsubasa Mitsutake, Hungu Jung, Takahiro Suzukawa, Shingo Taki, Naoki Imada, Tetsuji Inagawa, Hayato Araki, Osamu Araki
Summary: The purpose of this study was to examine the effects of frequency of single-joint hybrid assistive limb (HAL-SJ) use on upper limb motor function and activities of daily living in stroke patients. The results showed that high-frequency use of HAL-SJ led to significant improvements in shoulder, elbow, forearm, and Barthel index compared to low-frequency use. However, frequent use did not significantly increase the number of subjects with clinically meaningful changes in upper limb motor function.
DISABILITY AND REHABILITATION
(2023)
Article
Neurosciences
Yuji Iwamoto, Takeshi Imura, Ryo Tanaka, Tsubasa Mitsutake, Hungu Jung, Takahiro Suzukawa, Shingo Taki, Naoki Imada, Tetsuji Inagawa, Hayato Araki, Osamu Araki
Summary: This study developed a clinical prediction rule for identifying the characteristics of stroke patients whose upper limb motor function can improve with HAL-SJ rehabilitation using machine learning. According to the CHAID model, the FMA-UE score during the initiation of HAL-SJ rehabilitation was the most significant predictive factor, and the therapy was more effective in patients with moderate upper limb motor dysfunction and early initiation of HAL-SJ rehabilitation. The accuracy of the CHAID model was 0.89.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2022)
Article
Clinical Neurology
Shingo Matsuda, Fusao Ikawa, Toshikazu Hidaka, Shuhei Yamaguchi, Tetsuji Inagawa, Nobutaka Horie, Kaoru Kurisu, Yasuhiko Akiyama, Yoshihito Goto, Takeo Nakayama, Hitoshi Fukuda, Tetsuya Ueba, Masahiro Sasaki, Tatsuya Ishikawa, Norihito Shimamura, Hiroki Ohkuma
Summary: This study aimed to assess the estimated age-adjusted incidence rate of subarachnoid hemorrhage (SAH) in Shimane Prefecture, Japan, after 1998, following the previous Izumo Study. The results showed a declining trend of SAH incidence rate in Shimane Prefecture from 1999 to 2017.
NEUROLOGIA MEDICO-CHIRURGICA
(2022)
Article
Clinical Neurology
Akira Degami, Shingo Taki, Takeshi Imura, Yuji Iwamoto, Naoki Imada, Ryo Tanaka, Susumu Urakawa, Tetsuji Inagawa, Hayato Araki, Osamu Araki
Summary: The effect of early initiation of gait training using HAL on functional outcomes in stroke patients was investigated. The results showed that early initiation of gait training using HAL significantly improved motor function of the paralyzed lower limb and disability in stroke patients.
EUROPEAN NEUROLOGY
(2023)
Review
Clinical Neurology
Tetsuji Inagawa
Summary: Cerebral aneurysms are a significant cause of stroke, with details of their prevalence still under-researched. Autopsy studies show differences in age and gender for UCAs and RCAs, with a high rate of discovery of minute UCAs that may or may not progress to major UCAs and rupture.
NEUROSURGICAL REVIEW
(2022)
Article
Neurosciences
Hideo Ohba, Fusao Ikawa, Toshikazu Hidaka, Michitsura Yoshiyama, Shingo Matsuda, Yasuhiko Akiyama, Hiroki Ohkuma, Shuhei Yamaguchi, Tetsuji Inagawa, Kaoru Kurisu
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2020)
Article
Clinical Neurology
Guilu He, Jianhao Lin, Jing Ye, Fobao Huang, Changzhi Yan, Zesi Liu, Xiuming Zhou, Qiao Li, Liang Zhang
Summary: This article introduces long tunneled external ventricular drain (LTEVD), which effectively avoids multiple surgeries by connecting an external shunt valve. It allows visual control of drainage flow, prolongs catheter indwelling time, and eliminates the need for multiple surgeries.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Vinay Suresh, H. S. Suresh, Bharath Raju, Himanshu Jindal, Ahmad Ozair
Summary: This study investigated the outcomes of postoperative discitis treated with debridement and a novel technique focused on reducing outpatient antibiotic requirement in a low- and middle-income country (LMIC) setting. The results showed that patients with medically refractory postoperative discitis potentially have good outcomes after debridement plus 2-week local antibiotic instillation in LMICs.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Avi A. Gajjar, Shrey Patel, Raj Swaroop Lavadi, Rida Mitha, Rohit Prem Kumar, Tavis Taylor, Galal A. Elsayed, D. Kojo Hamilton, Nitin Agarwal
Summary: Art in neurosurgery has played a crucial role in the discipline for centuries. Medical illustrations help visualize anatomy and surgical procedures, contributing to education, surgical planning, and navigation.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Joaquin Perez Zabala, Yamila Basilotta Marquez, Romina Arganaraz, Beatriz Mantese
Summary: We present a low-cost and easily accessible adaptation system for stereotactic procedures in infants. By using a headband cast technique, a stereotactic biopsy was successfully performed in a 5-month-old patient, achieving precise targeting, histopathological diagnosis, and no associated complications.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Muhammad Kusdiansah, Arnau Benet, Yosuke Suzuki, Kenichi Haraguchi, Nakao Ota, Kosumo Noda, Rokuya Tanikawa
Summary: Fusiform vertebral artery aneurysms are difficult to treat, and endovascular and open microsurgical treatments are used for different situations. This report presents a case with complex anatomy and branch involvement and describes the treatment strategy used.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Victor M. Lu
Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Lapo Bonosi, Angelo Torrente, Filippo Brighina, Cateno Concetto Tito Petralia, Pietro Merlino, Chiara Avallone, Vincenzo Gulino, Roberta Costanzo, Lara Brunasso, Domenico Gerardo Iacopino, Rosario Maugeri
Summary: Corticocortical evoked potentials (CCEPs) have emerged as a valuable intraoperative monitoring technique in eloquent brain tumor surgery, aiding in preserving critical functional areas. Current research shows the potential of CCEPs in guiding surgical decision making, reducing the risk of postoperative neurological deficits, and mapping functional connectivity, but further research and standardization are needed.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang
Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Brian F. Saway, Conor M. Cunningham, Mustafa Ismail, Alejandro M. Spiotta
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Joanna M. Roy, Michael M. Covell, Carmelo Venero Jr, Christian A. Bowers
Summary: Early exposure to neurosurgery during medical school is critical for improving recruitment into the specialty. However, about 30% of medical schools in the U.S. lack a neurosurgery program, limiting students' exposure to the field. Virtual education, facilitated by webinars during the pandemic, has advantages such as global outreach and accessibility for international medical students. This review identifies and describes 16 educational resources, serving as a guide for medical students interested in neurosurgery.
WORLD NEUROSURGERY
(2024)