Article
Chemistry, Inorganic & Nuclear
Xuechun Pan, Jilou Ren, Jianfeng Zeng, Mingyue Liu, Zhenlan Fang, Qiang Ju
Summary: This study reports the systematic synthesis and fine control of monodisperse NaYbF4 nanoparticles through a canonical high-temperature co-precipitation method. The phase, morphology, and size of the nanoparticles can be rationally tuned by adjusting the reaction parameters. The optical properties and potential applications of NaYbF4:Er upconversion nanoparticles obtained under different conditions were investigated.
INORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Materials Science, Ceramics
Anming Li, Xuanbo Li, Junli Wang, Yansheng Guo, Chenggang Li, Weiguang Chen, Zhiwen Wang, Yanan Tang
Summary: Lanthanide-doped upconversion photoluminescent nanoparticles with unique anti-Stokes spectroscopic properties exhibit high absorption efficiency and optical heating capability, making them suitable for various applications. In this study, alpha-NaYbF4:Tm3+ crystalline nanoparticles were synthesized and showed intense ultraviolet upconversion photoluminescence and efficient optical heating under 980 nm laser excitation. The nanocrystals emitted multi-band luminescence with peaks in ultraviolet, blue, and red spectral regions.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Multidisciplinary
Xiaoli Luo, Qichen Chen, Yanni Zhang, Xiaowei He, Mingfeng Zhi, Zezheng Wang, Wu Zhao
Summary: In this study, NaYbF4 crystals were successfully synthesized using a hydrothermal method. The phase and morphology of the products were controlled by reaction times, PH values, and double solvents codoping. The results demonstrate that the photoluminescence intensity and color of the products can be tuned by manipulating their crystal phase, morphology, and surface defects. Furthermore, the synthesized UC red emission nanospheres show great potential in the field of biochemistry.
Article
Chemistry, Analytical
Ya-Nan Wei, Bo Lin, Yang Shu, Jian-Hua Wang
Summary: A novel fluorescent probe ANET was designed to target mitochondria for detecting Cys, showing advantages of ratiometric fluorescence, high selectivity, and a large Stokes shift. Imaging of Cys was confirmed in HepG2 cells using this probe.
Article
Chemistry, Multidisciplinary
Yufang Qiao, Shuqian Qiao, Xue Yu, Qiuhong Min, Chaojie Pi, Jianbei Qiu, Hongqing Ma, Jianhong Yi, Qiuqiang Zhan, Xuhui Xu
Summary: The development of bipyramidal UCNPs with super-bright red emission, achieved by introducing Tm3+ ions to alleviate energy loss at defective sites and significantly improve upconversion output, has allowed for penetration of plant cell walls and cell membrane infiltration. This work opens a new avenue for high resolution imaging of plant tissues.
Article
Chemistry, Multidisciplinary
Mikkel Baldtzer Liisberg, Satu Lahtinen, Ane Beth Sloth, Tero Soukka, Tom Vosch
Summary: The frequency encoded upconversion (FE-UPCON) widefield microscopy allows for multiplexed signal recovery in imaging by separating luminescence from spectrally and spatially overlapping trivalent lanthanide ions in upconversion nanoparticles. This technique utilizes periodic coexcitation with a secondary light source modulated at a chosen frequency to enhance the luminescence of the lanthanide ions of interest, enabling selective imaging and single UCNP detection without compromising sensitivity. FE-UPCON introduces a new dimension (frequency space) for multiplexed imaging with UCNPs.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Analytical
Zixu He, Diankai Liu, Ya Liu, Xiaohua Li, Wen Shi, Huimin Ma
Summary: A novel Golgi-targeted fluorescent probe has been developed for sensing and imaging nitric oxide (NO) in the Golgi apparatus. The probe shows accurate Golgi-targeting ability and high selectivity for NO. The study also reveals a significant increase of NO in the Golgi apparatus in an Alzheimer's disease model.
ANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Ceramics
A. Carro-Gastelum, S. Carmona-Tellez, S. Loera-Serna, L. Mariscal-Becerra, H. S. Murrieta, G. Alarcon-Flores, C. Falcony
Summary: The study investigated the upconversion emission properties of Tm3+ and Yb3+-doped Li-Gd2O3 ceramics in PS films, with high-intensity light emissions observed and enhanced crystallinity achieved through the use of lithium as a fluxing agent.
JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY
(2021)
Article
Multidisciplinary Sciences
Yanxin Zhang, Rongrong Wen, Jialing Hu, Daoming Guan, Xiaochen Qiu, Yunxiang Zhang, Daniel S. Kohane, Qian Liu
Summary: Manipulating topological arrangement can enhance upconversion luminescence in inorganic optical nanosystems. The outside-in architecture produces the maximum upconversion luminescence, around 6 times brighter than the inside-out architecture at the single-particle level. Monte Carlo simulation suggests that topology-dependent energy migration favors the upconversion luminescence of the outside-in structure.
NATURE COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Ying Chen, Il Minn, Steven P. Rowe, Alla Lisok, Samit Chatterjee, Mary Brummet, Sangeeta Ray Banerjee, Ronnie C. Mease, Martin G. Pomper
Summary: We have synthesized a series of near-infrared imaging agents targeting PSMA for use in fluorescence-guided surgery. The compounds were designed to improve pharmacokinetics by altering the linker between the PSMA-targeting urea moiety and the fluorophore. These compounds show potential for FGS in prostate, renal or other PSMA-expressing cancers.
Article
Materials Science, Multidisciplinary
Ranjita Misra, Manasi Das, Pronama Biswas, Anima Nanda
Summary: The development of Mn-doped ZnO nanocrystals successfully combines drug delivery and diagnosis. These nanocrystals exhibit nanometer range and fluorescence property, showing cytotoxic effects on tumor cells that can be eliminated by coating with a polymer. Moreover, surface conjugation of epidermal growth factor antibody on the nanocrystals enhances targeted delivery.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Materials Science, Biomaterials
Yijia Guan, Weijie Cao, Tao Li, Jieyi Qin, Qilong He, Xiaofeng Jia, Yuqing Li, Yuhua Zhang, Jianguo Liao
Summary: A novel platform for attenuating the neurotoxicity of Aβ has been constructed using functional upconversion nanoparticles (UCNPs@SiO2-ThS). These nanoparticles can inhibit the aggregation of Aβ monomers and disassemble Aβ fibrils through selective photooxidation under near-infrared light. The introduction of the Aβ-target peptide (KLVFF) further enhances the photooxygenation of Aβ, leading to reduced side effects and improved targeting compared to traditional chemotherapies and radiotherapies.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Optics
Anming Li, Dekang Xu, Yanan Tang, Zhiwen Wang, Zhaohan Li, Yueli Zhang
Summary: Lanthanide-doped upconversion nanocrystals were synthesized via hydrothermal method, with La3+ doping effectively increasing the transition probabilities of lanthanide ions and enhancing upconversion luminescence. The solid solution hosts showed improved photothermal conversion and luminescence intensity, suggesting potential for multifunctional applications in photoluminescence and photothermal fields. Rietveld refinements based on XRD data indicated the substitutional occupation of La3+ in Gd3+ sites in the formed pure phase solid solution Na(GdxLa1-x)(MoO4)(2).
JOURNAL OF LUMINESCENCE
(2021)
Article
Engineering, Environmental
Hui Liu, Haoyuan Li, Siyuan Xia, Shanshan Yu, Yujie Duan, Lei Wang, Hongxiang Zhu, Hui He
Summary: A cellulose nanocrystal-based upconversion ratiometric fluorescent nanoprobe was developed for pH monitoring and imaging by chemically bonding upconversion nanoparticles, fluorescein isothiocyanate, and rhodamine B acceptors using cellulose nanocrystals as a bridge. The probe addressed issues such as aggregation-caused quenching of dye, long donor-to-acceptor distance, and poor water dispersibility. It exhibited excellent selectivity, sensitivity, and visualization for intracellular pH levels of 5.0-7.4 with 980 nm excitation. The biocompatible probe inspired by chameleons enhanced penetration depth and showed promising results for pH monitoring and imaging in living cells and in vivo.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Rong Xu, Huiqun Cao, Danying Lin, Bin Yu, Junle Qu
Summary: Super-resolution fluorescence microscopy is a powerful tool for visualizing subcellular structures and probing biomolecular dynamics. Lanthanide-doped upconversion nanoparticles (UCNPs) have gained popularity as fluorescent probes due to their stable multicolor emissions, large anti-Stokes shifts, tunable luminescence lifetimes, and good biocompatibility. This review summarizes the optical and biological properties of UCNPs and their applications in super-resolution fluorescence microscopy, highlighting the importance of manipulating upconversion emissions, synthesizing smaller particles with bright luminescence, and integrating UCNPs with different imaging modes to meet the requirements of biological super-resolution imaging.
CELL REPORTS PHYSICAL SCIENCE
(2022)