Biophysical regulation of stem cell behavior within the niche

Nanotopography as modulator of human mesenchymal stem cell function

(2012) Karina Kulangara et al.   BIOMATERIALS

Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition

(2012) Jennifer L. Leight et al.   MOLECULAR BIOLOGY OF THE CELL

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Two Distinct Sites in Sonic Hedgehog Combine for Heparan Sulfate Interactions and Cell Signaling Functions

(2011) Shu-Chun Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate

(2011) Justin R. Tse et al.   PLoS One

Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells

(2011) Albert J. Keung et al.   STEM CELLS

Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro

(2010) Jennifer L. Young et al.   BIOMATERIALS

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Soft Substrates Promote Homogeneous Self-Renewal of Embryonic Stem Cells via Downregulating Cell-Matrix Tractions

(2010) Farhan Chowdhury et al.   PLoS One

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Controlled Growth Factor Delivery for Tissue Engineering

(2009) Prakriti Tayalia et al.   ADVANCED MATERIALS

Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules

(2009) Richard L. Carpenedo et al.   BIOMATERIALS

In situ elasticity modulation with dynamic substrates to direct cell phenotype

(2009) April M. Kloxin et al.   BIOMATERIALS

MT1-MMP controls human mesenchymal stem cell trafficking and differentiation

(2009) C. Lu et al.   BLOOD

Non-Linear Elasticity of Extracellular Matrices Enables Contractile Cells to Communicate Local Position and Orientation

(2009) Jessamine P. Winer et al.   PLoS One

Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11

(2009) Y.-S. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem cell fate dictated solely by altered nanotube dimension

(2009) S. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multivalency of Sonic Hedgehog Conjugated to Linear Polymer Chains Modulates Protein Potency

(2008) Samuel T. Wall et al.   BIOCONJUGATE CHEMISTRY

TGFβ/Activin/Nodal Pathway in Inhibition of Human Embryonic Stem Cell Differentiation by Mechanical Strain

(2008) Somen Saha et al.   BIOPHYSICAL JOURNAL

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Nanoscale Organization of Hedgehog Is Essential for Long-Range Signaling

(2008) Neha Vyas et al.   CELL

Substrate rigidity regulates Ca2+oscillation via RhoA pathway in stem cells

(2008) Tae-Jin Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tensile forces govern germ-layer organization in zebrafish

(2008) M. Krieg et al.   NATURE CELL BIOLOGY

Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics

(2008) Hari Shroff et al.   NATURE METHODS

Functional immobilization of signaling proteins enables control of stem cell fate

(2008) Kristin Alberti et al.   NATURE METHODS

Reproducible, Ultra High-Throughput Formation of Multicellular Organization from Single Cell Suspension-Derived Human Embryonic Stem Cell Aggregates

(2008) Mark D. Ungrin et al.   PLoS One

The effect of controlled growth factor delivery on embryonic stem cell differentiation inside fibrin scaffolds

(2008) Stephanie M. Willerth et al.   Stem Cell Research

Endogenous Matrix Metalloproteinase (MMP)-3 and MMP-9 Promote the Differentiation and Migration of Adult Neural Progenitor Cells in Response to Chemokines

(2008) Basam Z. Barkho et al.   STEM CELLS

Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories

(2008) Céline Liu Bauwens et al.   STEM CELLS