Glia: an emerging target for neurological disease therapy

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Multiple cellular and molecular mechanisms Are involved in human Aβ clearance by transplanted adult astrocytes

(2011) Rea Pihlaja et al.   GLIA

Glia: Initiators and progressors of pathology in Parkinson's disease

(2011) Glenda M. Halliday et al.   MOVEMENT DISORDERS

Specification of transplantable astroglial subtypes from human pluripotent stem cells

(2011) Robert Krencik et al.   NATURE BIOTECHNOLOGY

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

(2011) Amanda M Haidet-Phillips et al.   NATURE BIOTECHNOLOGY

Transplantation of Specific Human Astrocytes Promotes Functional Recovery after Spinal Cord Injury

(2011) Stephen J. A. Davies et al.   PLoS One

Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1G93A Mouse Model of ALS

(2011) Angelo C. Lepore et al.   PLoS One

Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo

(2011) S. T. Papadeas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

(2010) Maya K. Desai et al.   AMERICAN JOURNAL OF PATHOLOGY

Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice

(2010) L. Wang et al.   HUMAN MOLECULAR GENETICS

Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer’s disease

(2010) Guilian Tian et al.   JOURNAL OF NEUROCHEMISTRY

Neurodegeneration in a Transgenic Mouse Model of Multiple System Atrophy Is Associated with Altered Expression of Oligodendroglial-Derived Neurotrophic Factors

(2010) K. Ubhi et al.   JOURNAL OF NEUROSCIENCE

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

Stem cells in genetic myelin disorders

(2010) Kevin Kemp et al.   Regenerative Medicine

Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice

(2010) Xing-Long Gu et al.   Molecular Brain

Induction of Adult Human Bone Marrow Mesenchymal Stromal Cells into Functional Astrocyte-Like Cells: Potential for Restorative Treatment in Parkinson’s Disease

(2009) Merav Bahat-Stroomza et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem cell-based strategies for treating pediatric disorders of myelin

(2008) S. A. Goldman et al.   HUMAN MOLECULAR GENETICS

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

(2008) Jeffrey H Kordower et al.   NATURE MEDICINE

Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease

(2008) Angelo C Lepore et al.   NATURE NEUROSCIENCE

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

(2008) Siming Shen et al.   NATURE NEUROSCIENCE

Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter

(2008) Ragnhildur Káradóttir et al.   NATURE NEUROSCIENCE

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON