Article
Obstetrics & Gynecology
Silvia Vannuccini, Sara Clemenza, Emanuele Cassioli, Eleonora Rossi, Giovanni Castellini, Valdo Ricca, Felice Petraglia
Summary: Uterine fibroids (UFs) are associated with pain symptoms and heavy menstrual bleeding (HMB), leading to impaired quality of life. This study evaluated the global perception of stress and menstrual distress in patients with UFs. Patients with UFs had higher levels of perceived stress and menstrual distress compared to controls, with HMB playing a major role in determining these conditions.
REPRODUCTIVE SCIENCES
(2023)
Article
Obstetrics & Gynecology
Silvia Vannuccini, Varsha Jain, Hilary Critchley, Felice Petraglia
Summary: Menstruation is a monthly uterine bleeding that indicates reproductive health. Heavy menstrual bleeding (HMB) can be a useful clinical marker for diagnosing reproductive diseases. HMB can lead to iron depletion and anemia, and its underlying causes may vary.
FERTILITY AND STERILITY
(2022)
Article
Pharmacology & Pharmacy
Martina Orlandi, Silvia Vannuccini, Khadija El Aoufy, Maria Ramona Melis, Gemma Lepri, Gianluca Sambataro, Silvia Bellando-Randone, Serena Guiducci, Marco Matucci Cerinic, Felice Petraglia
Summary: This study evaluated gynecological symptoms and disorders in women of reproductive age with rheumatic diseases (RDs). The results showed that these patients commonly experienced menstrual irregularities, heavy menstrual bleeding, and dysmenorrhea, and their quality of life was significantly reduced. Therefore, it is important to inquire about gynecological symptoms in women with RDs and refer them to gynecologists for evaluation.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Hematology
Bethany Samuelson Bannow, Claire McLintock, Paula James
Summary: Abnormal or excessive menstrual bleeding affects a significant percentage of reproductive-aged women, with even higher rates seen in those on direct oral anticoagulants (DOACs). Management options include progestin-only therapies, combined hormonal contraceptives, and procedural therapies for women who have completed childbearing. Monitoring for iron deficiency and anemia is crucial in these cases, along with discussing management strategies early on.
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
(2021)
Review
Hematology
Wobke E. M. van Dijk, Marieke C. Punt, Karin P. M. van Galen, Jeanette van Leeuwen, A. Titia Lely, Roger E. G. Schutgens
Summary: This cross-sectional study assessed menstrual problems in premenopausal chronic ITP women and found that the majority of patients experienced clinical menstrual problems. The study also found that the pictorial bleeding assessment calendar (PBAC) and menorrhagia multiattribute scale (MMAS) were associated with heavy menstrual bleeding, but not related to platelet count. Patients using levonorgestrel intrauterine device (LNG-IUD) had lower bleeding scores, and MMAS scores were correlated with fatigue.
BRITISH JOURNAL OF HAEMATOLOGY
(2022)
Review
Biology
Maria Effrosyni Livanou, Alkis Matsas, Serena Valsami, Dimitrios T. Papadimitriou, Athanasios Kontogiannis, Panagiotis Christopoulos
Summary: Clotting Factor deficiencies present a diagnostic and therapeutic challenge, particularly for primary health care providers who are most likely to encounter these patients. Abnormal Uterine Bleeding, specifically Heavy Menstrual Bleeding, is a common manifestation and can lead to life-threatening bleeding in severe cases. Awareness and knowledge among physicians is crucial for proper management and prophylactic treatment options should be considered in some cases.
Article
Obstetrics & Gynecology
Blair G. G. Darney, Emily R. R. Boniface, Agathe Van Lamsweerde, Leo Han, Kristen A. A. Matteson, Sharon Cameron, Victoria Male, Juan Acuna, Eleonora Benhar, Jack T. T. Pearson, Alison Edelman
Summary: A small and transient increase in total bleeding quantity was observed following the first dose of the COVID-19 vaccine, but the total number of heavy bleeding days did not differ by vaccination status. The findings suggest that any changes in menstrual bleeding are minimal and temporary.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Sumita Mehta, Anshul Grover, Nalini Mittal, Pratibha Nanda, Ritu Khatuja, Azra Naseem
Summary: This study assessed the knowledge, attitude, and practices of women regarding menstrual hygiene and found that reusable sanitary pads are an effective and environmentally friendly alternative to disposable napkins.
JOURNAL OF PUBLIC HEALTH
(2022)
Article
Hematology
Mackenzie Parker, Maria Hannah, Ayesha Zia
Summary: This qualitative study explores the experiences of adolescents with heavy menstrual bleeding (HMB) and a bleeding disorder (BD). The study reveals that HMB is an isolating and stressful experience for adolescents, but a BD diagnosis can lead to identity formation and empowerment.
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
(2022)
Article
Public, Environmental & Occupational Health
Maryam Gharacheh, Fahimeh Ranjbar, Negar Hajinasab, Shima Haghani
Summary: The study found that among Iranian women, menstrual cups have high acceptability and safety, and are considered a suitable alternative for menstrual management. The majority of users learned about menstrual cups through social networks, and most were willing to recommend this product to other women.
Article
Clinical Neurology
Kathryn E. R. Kennedy, Chidera Onyeonwu, Sara Nowakowski, Lauren Hale, Charles C. Branas, William D. S. Killgore, Chloe C. A. Wills, Michael A. Grandner
Summary: This study analyzed data from 579 menstruating females and found significant associations between short sleep duration, poor sleep quality, and fatigue with heavier bleeding and menstrual cycle irregularity. Long sleep duration and symptoms of insomnia were not found to be related to these outcomes.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Obstetrics & Gynecology
Yeun Joo Shin, Sang Eun Won, Hae Nam Lee, Sa Jin Kim, Min Jeong Kim
Summary: In adolescent girls, irregular menstruation and menorrhagia are common with overlapping symptoms; ultrasound combined with medical history and physical examination can be useful for diagnosis and management of AUB, reducing unnecessary interventions; prompt recognition and active diagnosis are needed for cases requiring surgical treatment.
JOURNAL OF REPRODUCTIVE MEDICINE
(2021)
Article
Hematology
Bethany T. Samuelson Bannow, Vivia Chi, Paul Sochacki, Owen J. T. McCarty, Maureen K. Baldwin, Alison B. Edelman
Summary: The study investigated rates of heavy menstrual bleeding (HMB) in users of rivaroxaban and apixaban, finding an association between rivaroxaban use and the need for medical or surgical intervention for HMB. Most women did not have a documented menstrual history, indicating that many providers do not inquire about menstrual bleeding when initiating anticoagulant therapy. Menstruating women, especially those with a history of HMB, may be at increased risk for HMB requiring medical treatment depending on the type of OAC used.
THROMBOSIS RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Deborah Lancastle, Helena Kopp Kallner, Gabrielle Hale, Bethan Wood, Lauren Ashcroft, Holly Driscoll
Summary: This study aimed to develop a new 10-item measure of menstrual quality of life (the PERIOD-QOL) and found that it is a reliable tool. Women with heavy menstrual bleeding (HMB) reported significantly lower quality of life compared to other women.
Article
Chemistry, Medicinal
Afsane Bahrami, Asghar Zarban, Hadis Rezapour, Akram Agha Amini Fashami, Gordon A. Ferns
Summary: This study found that curcumin had a comparable effect to placebo in alleviating symptoms of PMS and dysmenorrhea. Further research with larger samples, higher doses of curcumin for longer durations, and perhaps in combination therapy is recommended for validation.
PHYTOTHERAPY RESEARCH
(2021)
Article
Primary Health Care
Katy Sivyer, Emma Teasdale, Kate Greenwell, Mary Steele, Daniela Ghio, Matthew J. Ridd, Amanda Roberts, Joanne R. Chalmers, Sandra Lawton, Sinead M. Langan, Fiona Cowdell, Emma Le Roux, Sylvia Wilczynska, Hywel C. Williams, Kim S. Thomas, Lucy Yardley, Miriam Santer, Ingrid Muller
Summary: This study developed an online behavioral intervention to help parents/carers manage and co-manage their child's eczema. Through qualitative research and interviews, barriers and facilitators to effective eczema management were identified and a prototype intervention was developed. The research found that parents/ carers had concerns about using emollients and topical corticosteroids, incomplete knowledge and skills around managing eczema, and reluctance to transition to co-managing eczema with their child. Think-aloud interviews revealed that while experienced parents/ carers felt they knew how to manage eczema, they still lacked some information about using treatments.
BRITISH JOURNAL OF GENERAL PRACTICE
(2022)
Letter
Allergy
Timothy D. H. Smith, Rebecca Townsend, Haleema Sadia Hussain, Miriam Santer, Robert J. Boyle
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Article
Primary Health Care
Eileen Sutton, Alison R. G. Shaw, Matthew J. Ridd, Miriam Santer, Amanda Roberts, Helen Baxter, Hywel C. Williams, Jonathan Banks
Summary: This study aimed to understand how parents and children experience and evaluate emollients. The findings suggest that there is no one-size-fits-all emollient and parents/children prioritize different aspects of emollients. Some participants reported that participating in the trial had changed their knowledge and behavior regarding emollients.
BRITISH JOURNAL OF GENERAL PRACTICE
(2022)
Article
Allergy
Hilary I. Allen, Ursula Pendower, Miriam Santer, Marion Groetch, Mitchell Cohen, Simon H. Murch, Hywel C. Williams, Daniel Munblit, Yitzhak Katz, Neeraj Gupta, Sabeen Adil, Justine Baines, Eefje G. P. M. de Bont, Matthew Ridd, Victoria L. Sibson, Alison McFadden, Jennifer J. Koplin, Josephine Munene, Michael R. Perkin, Scott H. Sicherer, Robert J. Boyle
Summary: This study investigates the issue of overdiagnosis of milk allergy and provides recommendations from non-conflicted experts to reduce overdiagnosis and support children with suspected milk allergy. The new recommendations suggest stricter diagnostic criteria, more support for breastfeeding, and less use of specialized formula.
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Article
Dermatology
Paul Leighton, Joanne R. Chalmers, Jonathan M. Batchelor, Andy Rogers, Perways Akram, Rachel H. Haines, Garry D. Meakin, Jennifer White, Jane C. Ravenscroft, Tracey H. Sach, Miriam Santer, Maxine E. Whitton, Viktoria Eleftheriadou, Kim S. Thomas
Summary: The study shows that combination treatment is safe and effective for patients with active, limited vitiligo. Providing combination treatment requires collaboration with medical physics and ongoing training and support.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Medicine, General & Internal
Kate Greenwell, Daniela Ghio, Katy Sivyer, Mary Steele, Emma Teasdale, Matthew J. Ridd, Amanda Roberts, Joanne R. Chalmers, Sandra Lawton, Sinead Langan, Fiona Cowdell, Emma Le Roux, Sylvia Wilczynska, Hannah Jones, Emilia Whittaker, H. C. Williams, Kim Suzanne Thomas, Lucy Yardley, Miriam Santer, Ingrid Muller
Summary: The study described the development of the Eczema Care Online (ECO) intervention through theory-based, evidence-based and person-based approaches, combined with qualitative research and think-aloud interviews. The findings showed that ECO received positive responses in terms of specific design and acceptability, and also provided in-depth understanding of the needs and challenges faced by young people with eczema.
Article
Dermatology
Kate Greenwell, Katy Sivyer, Laura Howells, Mary Steele, Matthew J. Ridd, Amanda Roberts, Amina Ahmed, Sandra Lawton, Sinead M. Langan, Julie Hooper, Sylvia Wilczynska, Paul Leighton, Gareth Griffiths, Tracey Sach, Paul Little, Hywel C. Williams, Kim S. Thomas, Lucy Yardley, Miriam Santer, Ingrid Muller
Summary: This study aimed to explore the views and experiences of individuals who have used the Eczema Care Online interventions, in order to understand their effectiveness and identify influencing factors. The findings suggest that the interventions are easy to use and trustworthy, and can help individuals manage their eczema by improving their understanding and confidence in eczema management, reducing treatment concerns, and enhancing treatment adherence and management of irritants/triggers.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Review
Nursing
Ingrid Muller, Daniela Ghio, Jasmine Mobey, Hannah Jones, Samantha Hornsey, Amy Dobson, Emma Maund, Miriam Santer
Summary: This study systematically reviewed and synthesized qualitative studies on parents/carers' views and experiences of infant crying. The findings suggest that infant crying has a substantial emotional impact on parents/carers, who reported using various soothing techniques but were desperate for effective treatment. Support was often perceived as lacking, and beliefs about maternal diet on breastmilk undermined parents' confidence in breastfeeding.
JOURNAL OF ADVANCED NURSING
(2023)
Article
Medicine, General & Internal
Miriam Santer, Megan Lawrence, Susanne Renz, Zina Eminton, Beth Stuart, Tracey H. Sach, Sarah Pyne, Matthew J. Ridd, Nick Francis, Irene Soulsby, Karen Thomas, Natalia Permyakova, Paul Little, Ingrid Muller, Jacqui Nuttall, Gareth Griffiths, Kim S. Thomas, Alison M. Layton
Summary: This study assessed the effectiveness of oral spironolactone for acne vulgaris in adult women. The results showed that spironolactone had significant improvement in acne symptoms and quality of life compared to placebo at 12 weeks and 24 weeks, with no serious adverse reactions reported. This suggests that spironolactone is a useful alternative to oral antibiotics for women with acne.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Editorial Material
Medicine, General & Internal
Miriam Santer, Alison Layton
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Medicine, Research & Experimental
Cherish Boxall, Susanne Renz, Zina Eminton, Jacqueline Nuttall, Alan Saji, Charlotte Cluff, Christopher Wilcox, Ingrid Muller, Alison M. Layton, Irene Soulsby, Miriam Santer
Summary: Decentralised clinical trials can effectively address recruitment and retention barriers, and the use of decentralised methods in dermatology trials can enhance recruitment and retention capabilities.
Letter
Medicine, General & Internal
Miriam Santer, Amanda Roberts, Ingrid Muller, Kim Thomas
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Miriam Santer, Megan Lawrence, Susanne Renz, Zina Eminton, Beth Stuart, Tracey H. Sach, Sarah Pyne, Matthew J. Ridd, Nick Francis, Irene Soulsby, Karen Thomas, Natalia Permyakova, Paul Little, Ingrid Muller, Jacqui Nuttall, Gareth Griffiths, Kim S. Thomas, Alison M. Layton
Summary: Oral spironolactone is effective in improving symptoms and quality of life for adult women with acne vulgaris, with better efficacy compared to oral antibiotics.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Meeting Abstract
Dermatology
Kim S. Thomas, Miriam Santer, Ingrid Muller, Taeko Becque, Beth Stuart, Julie Hooper, Tracey H. Sach, Matthew J. Ridd, Amanda Roberts, Amina Ahmed, Mary Steele, Kate Greenwell, Katy Sivyer, Sylvia Wilczynska, Hywel C. Williams, Joanne R. Chalmers, Paul Leighton, Laura M. Howells, Sandra Lawton, Gareth Griffiths, Jacqui Nuttall, Hayden Kirk, Sinead M. Langan, Lucy Yardley, Paul Little
ACTA DERMATO-VENEREOLOGICA
(2022)
Review
Medicine, General & Internal
Stephanie J. Lax, Jane Harvey, Emma Axon, Laura Howells, Miriam Santer, Matthew J. Ridd, Sandra Lawton, Sinead Langan, Amanda Roberts, Amina Ahmed, Ingrid Muller, Long Chiau Ming, Saumya Panda, Pavel Chernyshov, Ben Carter, Hywel C. Williams, Kim S. Thomas, Joanne R. Chalmers
Summary: Moderate and potent topical corticosteroids are likely more effective than mild ones in treating eczema, especially in moderate to severe cases. There is uncertainty about the advantage of very potent over potent topical corticosteroids. Frequency of use for potent topical corticosteroids does not seem to affect treatment outcomes significantly. Weekend (proactive) therapy with topical corticosteroids is probably more effective in preventing eczema relapse than reactive use. Adverse events are poorly reported, and the need for longer-term trials in individuals with mild eczema is emphasized.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)
Article
Public, Environmental & Occupational Health
Samantha Horn, Yana Litovsky, George Loewenstein
Summary: This study suggests that curiosity can be a useful tool in increasing demand for and engagement with aversive health information. By manipulating curiosity through various methods, researchers found that participants were more likely to view and engage with information about their drinking habits, cancer risk, and the sugar content in drinks. Overall, curiosity prompts provide a simple and effective way to increase engagement with aversive health information.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Sandra Gillner
Summary: Despite high expectations, the extensive and rapid adoption of AI in medical diagnostics has not been realized. This study investigates the perception and navigation of AI providers in complex healthcare systems, revealing their self-organization to increase adaptability and the practices utilized to mitigate tensions within the healthcare subsystems.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Fabian Duartea, Alvaro Jimenez-Molina
Summary: This study found that violence related to social protest has a significant impact on depressive symptoms, leading to an increase in depression among the population in Chile. The effect varies by gender and age, with a stronger influence on men and young adults.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Nick Graetz, Carl Gershenson, Sonya R. Porter, Danielle H. Sandler, Emily Lemmerman, Matthew Desmond
Summary: Investments in stable, affordable housing may be an important tool for improving population health. This study, using administrative data, found that high rent burden, increases in rent burden during midlife, and evictions were associated with increased mortality.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Wan Wei
Summary: This study explores the phenomenon of other patient participation in Traditional Chinese Medicine (TCM), uncovering the various roles that third parties can assume during medical interactions. The findings contribute to existing research on patient resistance and triadic medical interactions, providing insights into the dynamics and implications of third-party involvement in medical consultations.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Harry Scarbrough, Katie Rose M. Sanfilippo, Alexandra Ziemann, Charitini Stavropoulou
Summary: This paper examines the contribution of pilot implementation studies to the wider spread and sustainability of innovation in healthcare systems. Through an empirical examination of an innovation intermediary organization in the English NHS, the study finds that their work in mobilizing pilot-based evidence involves configuring to context, transitioning evidence, and managing the transition. The findings contribute to theory by showing how intermediary roles can support the effective transitioning of pilot-based evidence, leading to more widespread adoption and sustainability of innovation.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Marta Seiz, Leire Salazar, Tatiana Eremenko
Summary: This study examines the impact of maternal educational selection on birth outcomes during an economic recession, and finds that more educated mothers are more likely to give birth during high unemployment periods. Additionally, maternal education mitigates the adverse effects of unemployment on birth outcomes and is consistently associated with better perinatal health.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Jingyuan Shi, Hye Kyung Kim, Charles T. Salmon, Edson C. Tandoc Jr, Zhang Hao Goh
Summary: This study examines the influence of individual and collective norms on COVID-19 vaccination intention across eight Asian countries. The findings reveal nuanced patterns of how individual and collective social norms influence health behavioral decisions, depending on the degree of cultural tightness-looseness.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Elliot Friedman, Melissa Franks, Elizabeth Teas, Patricia A. Thomas
Summary: This study found that positive relations with others have a significant impact on functional limitations and longevity in aging adults, independent of social integration and social support.
SOCIAL SCIENCE & MEDICINE
(2024)
Article
Public, Environmental & Occupational Health
Zhuolin Pan, Yuqi Liu, Ye Liu, Ziwen Huo, Wenchao Han
Summary: This study examines the effects of age-friendly neighbourhood environment and functional abilities on life satisfaction among older adults in urban China. The findings highlight the importance of transportation, housing, and social and physical environment factors in influencing functional abilities and life satisfaction. The study provides valuable insights for policymakers in enhancing older adults' life satisfaction in the Chinese urban context.
SOCIAL SCIENCE & MEDICINE
(2024)