Longevity extension in Drosophila through gut-brain communication

(Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease

(2017) Thomas W. Buford   Microbiome

Gut microbiota signatures of longevity

(2016) Fanli Kong et al.   CURRENT BIOLOGY

Gut Microbiota and Extreme Longevity

(2016) Elena Biagi et al.   CURRENT BIOLOGY

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

(2016) Timothy G. Dinan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Anti-inflammaging effects of Lactobacillus brevis OW38 in aged mice

(2016) J.-J. Jeong et al.   Beneficial Microbes

Improving healthspan via changes in gut microbiota and fermentation

(2015) Michael J. Keenan et al.   AGE

Mitochondrial maintenance failure in aging and role of sexual dimorphism

(2015) John Tower   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Early thymus involution – Manifestation of an aging program or a program of development?

(2015) A. V. Khalyavkin et al.   BIOCHEMISTRY-MOSCOW

Mitochondria in health, aging and diseases: the epigenetic perspective

(2015) Patrizia D’Aquila et al.   BIOGERONTOLOGY

Comparative analysis of gut microbiota in elderly people of urbanized towns and longevity villages

(2015) Se-Hoon Park et al.   BMC MICROBIOLOGY

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

(2015) Saeed Shoaie et al.   Cell Metabolism

Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota – The “RISTOMED project”: Randomized controlled trial in healthy older people

(2015) Luzia Valentini et al.   CLINICAL NUTRITION

FOXO3: A Major Gene for Human Longevity - A Mini-Review

(2015) Brian J. Morris et al.   GERONTOLOGY

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

(2015) Rebecca I. Clark et al.   Cell Reports

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Gut Microbiota, Host Gene Expression, and Aging

(2014) Paola Patrignani et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

The Drosophila Imd Signaling Pathway

(2014) H. Myllymaki et al.   JOURNAL OF IMMUNOLOGY

GxE Interactions between FOXO Genotypes and Tea Drinking Are Significantly Associated with Cognitive Disability at Advanced Ages in China

(2014) Y. Zeng et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Dietary supplementation of milk fermented with probiotic Lactobacillus fermentum enhances systemic immune response and antioxidant capacity in aging mice

(2014) Rohit Sharma et al.   NUTRITION RESEARCH

Contribution of Intestinal Barrier Damage, Microbial Translocation and HIV-1 Infection Status to an Inflammaging Signature

(2014) Amanda K. Steele et al.   PLoS One

The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age-associated inflammation and oxidative stress in healthy rats

(2013) Yucun Niu et al.   AGING CELL

ACUTE EXPOSURE OFDrosophila melanogasterTO PARAQUAT CAUSES OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION

(2013) Ravikumar Hosamani et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

The key role of growth hormone–insulin–IGF-1 signaling in aging and cancer

(2013) Vladimir N. Anisimov et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The role of mitochondria in aging

(2013) Ana Bratic et al.   JOURNAL OF CLINICAL INVESTIGATION

Lactobacillus salivarius strain FDB89 induced longevity in Caenorhabditis elegans by dietary restriction

(2013) Yang Zhao et al.   JOURNAL OF MICROBIOLOGY

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Probiotics, Prebiotics and Immunomodulation of Gut Mucosal Defences: Homeostasis and Immunopathology

(2013) Holly Hardy et al.   Nutrients

Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster

(2013) Arshad Ayyaz et al.   Frontiers in Cellular and Infection Microbiology

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

(2012) Stacey Robida-Stubbs et al.   Cell Metabolism

PPARγ and stress: Implications for aging

(2012) Yvonne M. Ulrich-Lai et al.   EXPERIMENTAL GERONTOLOGY

Molecular Mechanisms of Aging and Immune System Regulation in Drosophila

(2012) Ioannis Eleftherianos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells

(2012) Marco Spinazzi et al.   Nature Protocols

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

(2012) M. Rera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short chain fatty acids and their receptors: new metabolic targets

(2012) Brian T. Layden et al.   Translational Research

The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster

(2011) Chunxu Wang et al.   AGE

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

(2011) Michael Rera et al.   Cell Metabolism

Evaluation of probiotic characteristics of newly isolated Lactobacillus spp.: Immune modulation and longevity

(2011) Jin Lee et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Oxidative stress, inflamm-aging and immunosenescence

(2011) Elvira S. Cannizzo et al.   Journal of Proteomics

Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production

(2011) Mitsuharu Matsumoto et al.   PLoS One

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

The Role of Mitochondria in Drosophila Aging

(2010) Jaehyoung Cho et al.   EXPERIMENTAL GERONTOLOGY

FOXO-dependent regulation of innate immune homeostasis

(2010) Thomas Becker et al.   NATURE

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Composition, variability, and temporal stability of the intestinal microbiota of the elderly

(2010) M. J. Claesson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

(2010) Sebastian Grönke et al.   PLoS Genetics

Brain mitochondrial dysfunction and oxidative damage in Parkinson’s disease

(2009) Ana Navarro et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue

(2009) Christine J Weydert et al.   Nature Protocols

Drosophila lifespan control by dietary restriction independent of insulin-like signaling

(2008) Kyung-Jin Min et al.   AGING CELL

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Inflammation and metabolic disorders

(2008) Mohamad Navab et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE