Pulsatile stretch as a novel modulator of amyloid precursor protein processing and associated inflammatory markers in human cerebral endothelial cells

Retinal vascular and structural changes are associated with amyloid burden in the elderly: ophthalmic biomarkers of preclinical Alzheimer’s disease

(2017) S.Mojtaba Golzan et al.   Alzheimers Research & Therapy

Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-α in cerebral microvessels

(2016) Tongrong He et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A new structural model of Alzheimer’s Aβ42 fibrils based on electron paramagnetic resonance data and Rosetta modeling

(2016) Lei Gu et al.   JOURNAL OF STRUCTURAL BIOLOGY

Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein

(2016) Saoussen Ben Halima et al.   Cell Reports

Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch

(2016) Yufeng Tian et al.   PLoS One

Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP

(2015) Giuseppe Faraco et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation

(2015) Folami Lamoke et al.   Journal of Neuroinflammation

Cerebral autoregulation, beta amyloid, and white matter hyperintensities are interrelated

(2015) Adam M. Brickman et al.   NEUROSCIENCE LETTERS

Preconditioning effects of physiological cyclic stretch on pathologically mechanical stretch-induced alveolar epithelial cell apoptosis and barrier dysfunction

(2014) Ju Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway

(2014) Yan Tan et al.   PLoS One

Long-term Effect of Telmisartan on Alzheimer’s Amyloid Genesis in SHR-SR After tMCAO

(2014) Tomoko Kurata et al.   Translational Stroke Research

Caveolin-1 scaffolding domain promotes leukocyte adhesion by reduced basal endothelial nitric oxide-mediated ICAM-1 phosphorylation in rat mesenteric venules

(2013) Sulei Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endothelial Junctional Adhesion Molecule-A Guides Monocytes Into Flow-Dependent Predilection Sites of Atherosclerosis

(2013) Martin M.N. Schmitt et al.   CIRCULATION

Active Stabilization of Human Endothelial Nitric Oxide Synthase mRNA by hnRNP E1 Protects against Antisense RNA and MicroRNAs

(2013) J. J. D. Ho et al.   MOLECULAR AND CELLULAR BIOLOGY

Pulse pressure is associated with Alzheimer biomarkers in cognitively normal older adults

(2013) D. A. Nation et al.   NEUROLOGY

Enhanced Aβ1–40 Production in Endothelial Cells Stimulated with Fibrillar Aβ1–42

(2013) Jayakumar Rajadas et al.   PLoS One

Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein

(2012) Livius V. d'Uscio et al.   CARDIOVASCULAR RESEARCH

Activation of NMDA Receptors Upregulates A Disintegrin and Metalloproteinase 10 via a Wnt/MAPK Signaling Pathway

(2012) X.-Z. Wan et al.   JOURNAL OF NEUROSCIENCE

Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons

(2011) Jessica B.S. Langbaum et al.   NEUROBIOLOGY OF AGING

Endothelial Nitric Oxide Modulates Expression and Processing of Amyloid Precursor Protein

(2010) Susan A. Austin et al.   CIRCULATION RESEARCH

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

(2010) Thorsten Pflanzner et al.   NEUROBIOLOGY OF AGING

Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury

(2009) David J Loane et al.   NATURE MEDICINE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols