Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance
出版年份 2017 全文链接
标题
Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-12-12
DOI
10.1038/s41598-017-18172-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent
- (2017) Marco Jost et al. MOLECULAR CELL
- Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
- (2017) Julia Joung et al. Nature Protocols
- CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions
- (2016) D. M. Munoz et al. Cancer Discovery
- Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting
- (2016) A. J. Aguirre et al. Cancer Discovery
- A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
- (2016) Konstantinos Tzelepis et al. Cell Reports
- Nucleosome breathing and remodeling constrain CRISPR-Cas9 function
- (2016) R Stefan Isaac et al. eLife
- Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
- (2016) Max A Horlbeck et al. eLife
- Nucleosomes impede Cas9 access to DNA in vivo and in vitro
- (2016) Max A Horlbeck et al. eLife
- Nucleosomes Inhibit Cas9 Endonuclease Activity in Vitro
- (2015) John M. Hinz et al. BIOCHEMISTRY
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- Highly efficient Cas9-mediated transcriptional programming
- (2015) Alejandro Chavez et al. NATURE METHODS
- High-throughput functional genomics using CRISPR–Cas9
- (2015) Ophir Shalem et al. NATURE REVIEWS GENETICS
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
- (2014) Marvin E. Tanenbaum et al. CELL
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Specific Gene Repression by CRISPRi System Transferred through Bacterial Conjugation
- (2014) Weiyue Ji et al. ACS Synthetic Biology
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
- (2013) Baohui Chen et al. CELL
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
- (2013) Pablo Perez-Pinera et al. NATURE METHODS
- CRISPR RNA–guided activation of endogenous human genes
- (2013) Morgan L Maeder et al. NATURE METHODS
- CRISPR interference (CRISPRi) for sequence-specific control of gene expression
- (2013) Matthew H Larson et al. Nature Protocols
- Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
- (2013) David Bikard et al. NUCLEIC ACIDS RESEARCH
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Tunable and Multifunctional Eukaryotic Transcription Factors Based on CRISPR/Cas
- (2013) Fahim Farzadfard et al. ACS Synthetic Biology
- RNA-guided genetic silencing systems in bacteria and archaea
- (2012) Blake Wiedenheft et al. NATURE
- CRISPR — a widespread system that provides acquired resistance against phages in bacteria and archaea
- (2007) Rotem Sorek et al. NATURE REVIEWS MICROBIOLOGY
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