Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity
出版年份 2017 全文链接
标题
Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-10-24
DOI
10.1038/s41598-017-14749-3
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma
- (2017) Khun Visith Keu et al. Science Translational Medicine
- Toxicities of chimeric antigen receptor T cells: recognition and management
- (2016) Jennifer N. Brudno et al. BLOOD
- Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies
- (2015) Laurent Poirot et al. CANCER RESEARCH
- Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice
- (2015) X. Liu et al. CANCER RESEARCH
- Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
- (2015) H. G. Caruso et al. CANCER RESEARCH
- Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens
- (2015) Michael Hebeisen et al. Frontiers in Immunology
- Side-by-Side Comparison of Commonly Used Biomolecules That Differ in Size and Affinity on Tumor Uptake and Internalization
- (2015) Jeerapond Leelawattanachai et al. PLoS One
- CAR T Cells for Solid Tumors
- (2014) Sunitha Kakarla et al. CANCER JOURNAL
- Single and Dual Amino Acid Substitutions in TCR CDRs Can Enhance Antigen-Specific T Cell Functions
- (2014) Paul F. Robbins et al. JOURNAL OF IMMUNOLOGY
- Target Antigen Density Governs the Efficacy of Anti–CD20-CD28-CD3 ζ Chimeric Antigen Receptor–Modified Effector CD8+T Cells
- (2014) Keisuke Watanabe et al. JOURNAL OF IMMUNOLOGY
- Preclinical Evaluation of a High-Affinity 18F-Trifluoroborate Octreotate Derivative for Somatostatin Receptor Imaging
- (2014) Z. Liu et al. JOURNAL OF NUCLEAR MEDICINE
- ICAM-1 as a molecular target for triple negative breast cancer
- (2014) P. Guo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells
- (2013) M. Hudecek et al. CLINICAL CANCER RESEARCH
- Virus-mimetic polyplex particles for systemic and inflammation-specific targeted delivery of large genetic contents
- (2013) S Kang et al. GENE THERAPY
- Intercellular adhesion molecule-1 (ICAM-1) expression correlates with oral cancer progression and induces macrophage/cancer cell adhesion
- (2013) Yu Usami et al. INTERNATIONAL JOURNAL OF CANCER
- Reassessing target antigens for adoptive T-cell therapy
- (2013) Christian S Hinrichs et al. NATURE BIOTECHNOLOGY
- Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
- (2013) Stephan A. Grupp et al. NEW ENGLAND JOURNAL OF MEDICINE
- T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
- (2013) S. Zhong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
- (2013) R. J. Brentjens et al. Science Translational Medicine
- Tumor suppression via paclitaxel-loaded drug carriers that target inflammation marker upregulated in tumor vasculature and macrophages
- (2012) Spencer Park et al. BIOMATERIALS
- The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy
- (2012) Salvatore Valitutti Frontiers in Immunology
- Visualizing and Quantifying Acute Inflammation Using ICAM-1 Specific Nanoparticles and MRI Quantitative Susceptibility Mapping
- (2011) Richard Wong et al. ANNALS OF BIOMEDICAL ENGINEERING
- Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
- (2011) David L. Porter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
- (2010) J. N. Kochenderfer et al. BLOOD
- Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function
- (2010) D. A. Schmid et al. JOURNAL OF IMMUNOLOGY
- A Novel Facile Method of Labeling Octreotide with 18F-Fluorine
- (2010) P. Laverman et al. JOURNAL OF NUCLEAR MEDICINE
- Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
- (2010) Richard A Morgan et al. MOLECULAR THERAPY
- T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis
- (2010) Maria R Parkhurst et al. MOLECULAR THERAPY
- Positron Emission Tomography-Computed Tomography Standardized Uptake Values in Clinical Practice and Assessing Response to Therapy
- (2010) Paul E. Kinahan et al. SEMINARS IN ULTRASOUND CT AND MRI
- Attenuated T Cell Responses to a High-Potency Ligand In Vivo
- (2010) Emily Corse et al. PLOS BIOLOGY
- The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
- (2009) M. A. Cheever et al. CLINICAL CANCER RESEARCH
- A Novel Method of 18F Radiolabeling for PET
- (2009) W. J. McBride et al. JOURNAL OF NUCLEAR MEDICINE
- Noninvasive detection of therapeutic cytolytic T cells with 18F–FHBG PET in a patient with glioma
- (2008) Shahriar S Yaghoubi et al. Nature clinical practice. Oncology
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