Article
Clinical Neurology
Zhi-Yin Zhang, Jing-Jing Yu, Wan-Ting Zeng, Min-Cong Zhou, Chen-Chi Duan, Lin-Ling Zhu
Summary: This study investigated the association between antenatal depression and adverse perinatal outcomes in a Chinese population. The results showed that pregnant women with antenatal depressive symptoms were more likely to have preterm delivery and cesarean section. Therefore, screening and treatment for antenatal depression are necessary during prenatal care.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Obstetrics & Gynecology
Yoko Okamoto, Satomi Doi, Aya Isumi, Junichi Sugawara, Kazuhisa Maeda, Shoji Satoh, Takeo Fujiwara, Nobuaki Mitsuda
Summary: The objective of this study was to develop and validate the Social Life Impact for Mother (SLIM) scale in order to identify mothers in Japan who need social support postpartum. The results showed that the SLIM scale, consisting of nine risk factors for postpartum social problems, predicted these problems with moderate accuracy. Therefore, obstetricians can use the SLIM scale during prenatal check-ups to detect mothers with postpartum social problems.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Nutrition & Dietetics
Lin-Chien Chan, Hsiu-Hui Wang, Mark L. Wahlqvist, Cheng-Chieh Liu, Jah-Yao Liu, Meei-Shyuan Lee
Summary: To promote maternal and infant health, optimizing the dietary pattern of pregnant women to reduce perinatal depression is necessary. This study found that dairy, vegetable, and fruit intakes among pregnant women were below recommended levels and that depressive symptoms were prevalent in late pregnancy and postpartum. Depressive symptoms in the pre- and postnatal periods were positively correlated, and approximately 55% of pre-delivery depression cases also experienced depression postpartum. The study also found that higher scores in an omnivorous dietary pattern were associated with a reduced risk of depression.
MATERNAL AND CHILD NUTRITION
(2023)
Article
Medicine, General & Internal
Michelle Z. L. Kee, Andrea Cremaschi, Maria De Iorio, Helen Chen, Tina Montreuil, Tuong Vi Nguyen, Sylvana M. Cote, Kieran J. O'Donnell, Gerald F. Giesbrecht, Nicole Letourneau, Shiao Yng Chan, Michael J. Meaney
Summary: This study found that the trajectories of depressive symptoms remain stable from pregnancy to the perinatal period, contradicting the emphasis on postpartum depression in some health policy guidelines. Interventions and public health initiatives should focus on reducing depressive symptoms during pregnancy.
Review
Psychiatry
Jiaying Li, Juan Yin, Ahmed Waqas, Zeyu Huang, Hongji Zhang, Manqing Chen, Yufei Guo, Atif Rahman, Lei Yang, Xiaomei Li
Summary: This study evaluated the health-related quality of life (HRQoL) of mothers with perinatal depression and compared them with non-depressed mothers. The findings showed that mothers with perinatal depression reported significantly poorer scores across all domains of quality of life compared to non-depressed mothers. There was no significant difference in HRQoL scores between mothers with antepartum and postpartum depression. Mothers with perinatal depression in higher-income countries reported higher disability in role-physical and social functioning domains compared to those from lower-income countries.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychiatry
Pragya Lodha, Tasfia Jahangir, Sagar Karia, Avinash DeSousa, Raghu Appasani, Mellissa Withers
Summary: Perinatal depression has long-term adverse effects on maternal mental health, maternal-child interactions, and child development. A study in India suggests that socio-cultural factors may contribute to the risk of perinatal depression. The study highlights the low awareness and misconceptions about perinatal depression among pregnant mothers and their family members.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Medicine, General & Internal
Laure Nicolet, Amir Moayedoddin, Joel Djatche Miafo, Daniel Nzebou, Beat Stoll, Emilien Jeannot
Summary: The study found a high prevalence of depressive disorder symptoms among teenage or young pregnant women, estimated to be 70.0%. This risk is significantly increased by factors such as unintended pregnancy, being separated or single, experiencing depression and anxiety before childbirth, abortion experience, and domestic violence.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychology, Developmental
Sarah Hampton, Carrie Allison, Ezra Aydin, Simon Baron-Cohen, Rosemary Holt
Summary: Autistic people may experience higher levels of stress, depression, and anxiety during pregnancy and after giving birth, but they are equally likely as non-autistic parents to engage in positive parenting behaviors. It is important to provide effective screening and support for perinatal mental health conditions for autistic individuals.
Article
Clinical Neurology
Kenta Matsumura, Kei Hamazaki, Akiko Tsuchida, Haruka Kasamatsu, Hidekuni Inadera
Summary: The study found that low social support during pregnancy is associated with increased risk of perinatal/postpartum depression, indicating the importance of timely and sufficient social support for prevention and recovery.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Clinical
Sarah Tebeka, Yann Le Strat, Bruno Etain, Margaux Ray, Jimmy Mullaert, Caroline Dubertret
Summary: Childhood trauma is associated with an increased risk of perinatal depression, anxiety, and suicide attempts among women. The number of types of childhood trauma experienced also contributes to the risk of perinatal depression. Women with a history of childhood trauma may require specialized prenatal care to address and prevent perinatal depression.
JOURNAL OF CLINICAL PSYCHIATRY
(2021)
Article
Multidisciplinary Sciences
Taylor Winter, Paul E. Jose, Benjamin C. Riordan, Boris Bizumic, Ted Ruffman, John A. Hunter, Todd K. Hartman, Damian Scarf
Summary: This study investigates the relationship between political orientation and right-wing authoritarianism, finding that both left-leaning and right-leaning individuals endorsed authoritarian submission during the pandemic. However, typical relationships between political orientation and authoritarian aggression and conventionalism were observed.
Article
Clinical Neurology
Megan Galbally, Stuart Watson, Andrew J. Lewis, Josephine Power, Niels Buus, Marinus van IJzendoorn
Summary: This study examined the relationship between maternal attachment, perinatal depression, and emotional wellbeing. The findings showed that maternal attachment, specifically the Non-Autonomous states of mind, was associated with higher cortisol levels during pregnancy and higher depressive symptoms throughout pregnancy and the postpartum period. Mothers with depression and Non-Autonomous states of mind also reported higher parenting stress after childbirth. There was no significant intergenerational concordance between attachment classifications. Further research is needed to understand the role of maternal attachment in perinatal depression and emotional wellbeing.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Arpana Pokharel, Sharad Philip, Aruna Pokharel, Nisha Acharya, Salina Dahal, Ramdas Ransing
Summary: This cross-sectional study aimed to evaluate the postnatal depression and mental health of teenage mothers in Nepal. The results showed a high proportion of teenage mothers experiencing depressive symptoms and poor mental health, suggesting the need for screening and supportive care.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Clinical Neurology
Rannveig S. Osnes, Malin Eberhard-Gran, Turid Follestad, Havard Kallestad, Gunnar Morken, John Olav Roaldset
Summary: This study investigated the association between mid-pregnancy insomnia and depression during mid-pregnancy and 8 weeks postpartum, as well as differences in sleep-related characteristics between primiparous and multiparous women. The results showed that mid-pregnancy insomnia was significantly associated with concurrent depression, but not with postpartum depression. Additionally, sleep efficiency decreased from mid-pregnancy to postpartum, with primiparous women reporting worse sleep efficiency than multiparous women. This suggests that mid-pregnancy insomnia may be an indicator for concurrent depression but not a predictor for postpartum depression.
BEHAVIORAL SLEEP MEDICINE
(2021)
Article
Medicine, General & Internal
Ayesha M. Bilal, Emma Fransson, Emma Brann, Allison Eriksson, Mengyu Zhong, Karin Giden, Ulf Elofsson, Cathrine Axfors, Alkistis Skalkidou, Fotios C. Papadopoulos
Summary: This study aims to develop models to predict high-risk women for mental and somatic complications using digital phenotyping data from the Mom2B smartphone application. Active and passive data collection will be used to establish a participant's digital phenotype, and advanced machine learning techniques will be applied to develop accurate algorithms for prediction.
Review
Genetics & Heredity
Hidekazu Kato, Hiroki Kimura, Itaru Kushima, Nagahide Takahashi, Branko Aleksic, Norio Ozaki
Summary: Schizophrenia is a complex and chronic psychiatric disorder with a high heritability. Despite the lack of diagnostic tests or biomarkers, genetic research has made significant progress in our understanding of the genetic architecture of schizophrenia, including rare copy number variations (CNVs), rare single-nucleotide variants (SNVs), and common single-nucleotide polymorphisms (SNPs). These genetic variants play crucial roles in the pathogenesis of schizophrenia. New approaches such as CRISPR-based genetics and induced pluripotent stem cell technology can help further study the functional analysis of these variants. These advancements will contribute to the development of pathology-based therapeutics and a better understanding of the pathophysiology of schizophrenia.
JOURNAL OF HUMAN GENETICS
(2023)
Article
Ophthalmology
Akiko Hanyuda, Atsushi Goto, Masahiro Nakatochi, Yoichi Sutoh, Akira Narita, Shiori Nakano, Ryoko Katagiri, Kenji Wakai, Naoyuki Takashima, Teruhide Koyama, Kokichi Arisawa, Issei Imoto, Yukihide Momozawa, Kozo Tanno, Atsushi Shimizu, Atsushi Hozawa, Kengo Kinoshita, Taiki Yamaji, Norie Sawada, Masao Iwagami, Kenya Yuki, Kazuo Tsubota, Kazuno Negishi, Keitaro Matsuo, Masayuki Yamamoto, Makoto Sasaki, Shoichiro Tsugane, Motoki Iwasaki
Summary: This study conducted a Mendelian randomization analysis to assess the causal association between genetically predicted glycemic traits and the risk of primary open-angle glaucoma (POAG). The results did not provide strong evidence to support the association between genetically predicted glycemic traits and POAG in the Japanese population.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Letter
Rheumatology
Yu Toyoda, Masahiro Nakatochi, Akiyoshi Nakayama, Yusuke Kawamura, Hirofumi Nakaoka, Kenji Wakai, Keitaro Matsuo, Hirotaka Matsuo
Article
Dentistry, Oral Surgery & Medicine
K. Suzuki, N. Nishio, H. Kimura, T. Tokura, S. Kishi, N. Ozaki, Y. Fujimoto, M. Sone
Summary: The aim of this study was to assess the changes in quality of life and psychological distress in patients with tongue cancer undergoing different surgeries. The results showed that patients who underwent total/subtotal glossectomy (TG) had worse general health and social functioning, as well as higher levels of depression, compared to those who underwent extended hemiglossectomy (HG) with free flap transfer. This suggests that patients in the TG group may experience social isolation and psychological distress even 12 months after surgery, while patients in the HG group had similar outcomes to the general population.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2023)
Article
Pharmacology & Pharmacy
Rinako Tanaka, Jingzhu Liao, Kazuhiro Hada, Daisuke Mori, Taku Nagai, Tetsuo Matsuzaki, Toshitaka Nabeshima, Kozo Kaibuchi, Norio Ozaki, Hiroyuki Mizoguchi, Kiyofumi Yamada
Summary: Copy-number variations in the ARHGAP10 gene are associated with schizophrenia. Model mice with double-hit mutations in the Arhgap10 gene exhibit schizophrenia-like symptoms, such as altered spine density and cognitive dysfunction. The study found that the activation of the RhoA/Rho-kinase signaling pathway is involved in these symptoms. Fasudil, a Rho-kinase inhibitor, can ameliorate the symptoms in the model mice.
PHARMACOLOGICAL RESEARCH
(2023)
Letter
Clinical Neurology
Shusei Arafuka, Hirotaka Sekiguchi, Hiroshige Fujishiro, Shuji Iritani, Youta Torii, Chikako Habuchi, Mari Yoshida, Yasushi Iwasaki, Norio Ozaki, Kiyoshi Fujita
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2023)
Letter
Clinical Neurology
Masahiro Ohgidani, Itaru Kushima, Shogo Inamine, Sota Kyuragi, Noriaki Sagata, Tomohiro Nakao, Shigenobu Kanba, Norio Ozaki, Takahiro A. Kato
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2023)
Article
Endocrinology & Metabolism
Takuya Sakashita, Yasuyuki Nakamura, Yoichi Sutoh, Atsushi Shimizu, Tsuyoshi Hachiya, Yayoi Otsuka-Yamasaki, Naoyuki Takashima, Aya Kadota, Katsuyuki Miura, Yoshikuni Kita, Hiroaki Ikezaki, Jun Otonari, Keitaro Tanaka, Chisato Shimanoe, Teruhide Koyama, Isao Watanabe, Sadao Suzuki, Hiroko Nakagawa-Senda, Asahi Hishida, Takashi Tamura, Yasufumi Kato, Rieko Okada, Kiyonori Kuriki, Sakurako Katsuura-Kamano, Takeshi Watanabe, Shiroh Tanoue, Chihaya Koriyama, Isao Oze, Yuriko N. Koyanagi, Yohko Nakamura, Miho Kusakabe, Masahiro Nakatochi, Yukihide Momozawa, Kenji Wakai, Keitaro Matsuo
Summary: This study investigates the association between HbA1c and blood glucose levels and their corresponding genetic loci in a non-diabetic Japanese population. The study identifies KCNQ1 and TMC6 loci as being associated with HbA1c levels, but no replication is found for the loci associated with blood glucose levels. Furthermore, the variant rs2299620 in KCNQ1 shows heterogeneity in its effect on HbA1c levels based on BMI grouping.
DIABETOLOGY INTERNATIONAL
(2023)
Article
Public, Environmental & Occupational Health
Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, Ippei Shimoshikiryo, Daisaku Nishimoto, Keiichi Shimatani, Toshiro Takezaki, Hiroaki Ikezaki, Masayuki Murata, Megumi Hara, Yuichiro Nishida, Takashi Tamura, Asahi Hishida, Mako Nagayoshi, Rieko Okada, Keitaro Matsuo, Hidemi Ito, Haruo Mikami, Yohko Nakamura, Takahiro Otani, Sadao Suzuki, Teruhide Koyama, Etsuko Ozaki, Kiyonori Kuriki, Naoyuki Takashima, Naoko Miyagawa, Kokichi Arisawa, Sakurako Katsuura-Kamano, Yukihide Momozawa, Michiaki Kubo, Kenji Takeuchi, Kenji Wakai
Summary: The study evaluated the population-based impact of smoking, drinking, and genetic factors on low HDL-C levels using data from the J-MICC Study. The findings showed that smoking, drinking, and certain genetic variants were associated with HDL-C levels, but there was no significant gene-environment interaction. The population-based impact of the genetic factor CETP rs3764261 was higher than that of smoking and lower than that of drinking.
JOURNAL OF EPIDEMIOLOGY
(2023)
Editorial Material
Clinical Neurology
Norio Ozaki, Teiji Kimura, Tetsuro Kikuchi, Takeo Ishiyama
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2023)
Article
Neurosciences
Hiroki Kimura, Itaru Kushima, Masahiro Banno, Toshiya Inada, Akira Yoshimi, Branko Aleksic, Norio Ozaki
Summary: This article reports detailed clinical cases of four patients with schizophrenia and 16p13.11 duplication, with one patient having treatment-resistant schizophrenia and an additional pathogenic rare CNV. Two of the four patients had potential environmental risk factors. The results suggest that a genetic cohort study would be useful in understanding the variable expressivity of 16p13.11 duplication and elucidating the pathophysiology of schizophrenia.
NEUROPSYCHOPHARMACOLOGY REPORTS
(2023)
Editorial Material
Clinical Neurology
Seiko Miyata, Kunihiro Iwamoto, Norio Ozaki
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2023)
Meeting Abstract
Clinical Neurology
Seiko Miyata, Kunihiro Iwamoto, Ippei Okada, Akihiro Fujimoto, Yuki Kogo, Manabu Amano, Nao Matsuyama, Norio Ozaki
Article
Optics
G. Cristoforetti, P. Koester, S. Atzeni, D. Batani, S. Fujioka, Y. Hironaka, S. Huller, T. Idesaka, K. Katagiri, K. Kawasaki, R. Kodama, D. Mancelli, Ph. Nicolai, N. Ozaki, A. Schiavi, K. Shigemori, R. Takizawa, T. Tamagawa, D. Tanaka, A. Tentori, Y. Umeda, A. Yogo, L. A. Gizzi
Summary: The interaction between laser and plasma as well as the generation of hot electrons were studied in an experiment relevant to direct-drive inertial confinement fusion. High-energy electrons with temperatures of 20-50 keV were mainly produced by the damping of electron plasma waves driven by two-plasmon decay (TPD). Stimulated Raman scattering (SRS) was observed in a near-threshold growth regime and described by an analytical model, indicating a more vigorous growth driven by multiple beams compared to single-beam laser intensity.
HIGH POWER LASER SCIENCE AND ENGINEERING
(2023)
Article
Obstetrics & Gynecology
Takafumi Ushida, Masahiro Nakatochi, Yumiko Kobayashi, Noriyuki Nakamura, Kazuya Fuma, Yukako Iitani, Kenji Imai, Yoshiaki Sato, Masahiro Hayakawa, Hiroaki Kajiyama, Tomomi Kotani, Neonatal Research Network Of Japan
Summary: Antenatal corticosteroid (ACS) treatment has beneficial effects on mortality, respiratory distress syndrome, and adverse composite outcomes in extremely and very preterm infants with small for gestational age (SGA), with similar efficacy on all neonatal outcomes except for respiratory distress syndrome observed in non-SGA infants.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
