Expression of human endogenous retrovirus-K is strongly associated with the basal-like breast cancer phenotype

Human endogenous retroviruses: friend or foe?

(2016) Robin A. Weiss   APMIS

Discovery of unfixed endogenous retrovirus insertions in diverse human populations

(2016) Julia Halo Wildschutte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Genetic Engineering of T Cells to Target HERV-K, an Ancient Retrovirus on Melanoma

(2015) J. Krishnamurthy et al.   CLINICAL CANCER RESEARCH

MicroRNA-Based Therapeutic Strategies for Targeting Mutant and Wild Type RAS in Cancer

(2015) Sriganesh B. Sharma et al.   DRUG DEVELOPMENT RESEARCH

Human endogenous retroviruses sustain complex and cooperative regulation of gene-containing loci and unannotated megabase-sized regions

(2015) Martin Sokol et al.   Retrovirology

Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation

(2015) Ze-Yi Zheng et al.   Cell Reports

Chimeric antigen receptor T cells targeting HERV-K inhibit breast cancer and its metastasis through downregulation of Ras

(2015) Fuling Zhou et al.   OncoImmunology

Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes

(2015) Xiaoping Su et al.   Oncotarget

Mammary Tumors Initiated by Constitutive Cdk2 Activation Contain an Invasive Basal-like Component

(2015) Patrick E. Corsino et al.   NEOPLASIA

Circulating Tumor Cell Analysis in Metastatic Triple-Negative Breast Cancers

(2014) M. J. M. Magbanua et al.   CLINICAL CANCER RESEARCH

Cytotoxicity of Human Endogenous Retrovirus K-Specific T Cells toward Autologous Ovarian Cancer Cells

(2014) K. Rycaj et al.   CLINICAL CANCER RESEARCH

MOSAIK: A Hash-Based Algorithm for Accurate Next-Generation Sequencing Short-Read Mapping

(2014) Wan-Ping Lee et al.   PLoS One

Targeting TBP-Associated Factors in Ovarian Cancer

(2014) Jennifer R. Ribeiro et al.   Frontiers in Oncology

Human endogenous retrovirus type K antibodies and mRNA as serum biomarkers of early-stage breast cancer

(2013) Feng Wang-Johanning et al.   INTERNATIONAL JOURNAL OF CANCER

The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

(2013) T Chen et al.   LEUKEMIA

Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers

(2013) Sabine M. Brouxhon et al.   MOLECULAR CARCINOGENESIS

An Integrated Approach to Uncover Driver Genes in Breast Cancer Methylation Genomes

(2013) Xiaopei Shen et al.   PLoS One

The Majority of Primate-Specific Regulatory Sequences Are Derived from Transposable Elements

(2013) Pierre-Étienne Jacques et al.   PLoS Genetics

TBCRC 001: Randomized Phase II Study of Cetuximab in Combination With Carboplatin in Stage IV Triple-Negative Breast Cancer

(2012) Lisa A. Carey et al.   JOURNAL OF CLINICAL ONCOLOGY

Immunotherapeutic Potential of Anti-Human Endogenous Retrovirus-K Envelope Protein Antibodies in Targeting Breast Tumors

(2012) Feng Wang-Johanning et al.   JNCI-Journal of the National Cancer Institute

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Active kinase profiling, genetic and pharmacological data define mTOR as an important common target in triple-negative breast cancer

(2012) J C Montero et al.   ONCOGENE

Oncogenic and Wild-type Ras Play Divergent Roles in the Regulation of Mitogen-Activated Protein Kinase Signaling

(2012) Amy Young et al.   Cancer Discovery

Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses

(2011) Ravi P Subramanian et al.   Retrovirology

Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome

(2010) Andrey I. Khramtsov et al.   AMERICAN JOURNAL OF PATHOLOGY

Human Endogenous Retrovirus K Triggers an Antigen-Specific Immune Response in Breast Cancer Patients

(2008) F. Wang-Johanning et al.   CANCER RESEARCH

A Single Amino Acid Substitution in a Segment of the CA Protein within Gag That Has Similarity to Human Immunodeficiency Virus Type 1 Blocks Infectivity of a Human Endogenous Retrovirus K Provirus in the Human Genome

(2008) D. J. Heslin et al.   JOURNAL OF VIROLOGY