EpEX/EpCAM and Oct4 or Klf4 alone are sufficient to generate induced pluripotent stem cells through STAT3 and HIF2α

Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer

(2015) Alex Gregorieff et al.   NATURE

Core Pluripotency Factors Directly Regulate Metabolism in Embryonic Stem Cell to Maintain Pluripotency

(2015) Hyunsoo Kim et al.   STEM CELLS

HIF-2α Regulates NANOG Expression in Human Embryonic Stem Cells following Hypoxia and Reoxygenation through the Interaction with an Oct-Sox Cis Regulatory Element

(2014) Raffaella Petruzzelli et al.   PLoS One

Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers

(2013) Jian Shu et al.   CELL

Reprogramming of Human Fibroblasts to Pluripotency with Lineage Specifiers

(2013) Nuria Montserrat et al.   Cell Stem Cell

A versatile, highly efficient, and potentially safer piggyBac transposon system for mammalian genome manipulations

(2013) Yaa-Jyuhn James Meir et al.   FASEB JOURNAL

Induced pluripotent stem cells: origins, applications, and future perspectives

(2013) Jing Zhao et al.   Journal of Zhejiang University-SCIENCE B

Epithelial Cell Adhesion Molecule Regulates Tumor Initiation and Tumorigenesis via Activating Reprogramming Factors and Epithelial-Mesenchymal Transition Gene Expression in Colon Cancer

(2012) Cheng-Wei Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Highly Coordinated Proteome Dynamics during Reprogramming of Somatic Cells to Pluripotency

(2012) Jenny Hansson et al.   Cell Reports

β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism

(2011) Kevin F. Kelly et al.   Cell Stem Cell

IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer

(2011) M. S. Anglesio et al.   CLINICAL CANCER RESEARCH

E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming

(2011) Torben Redmer et al.   EMBO REPORTS

Epithelial Cell Adhesion Molecule (EpCAM) Complex Proteins Promote Transcription Factor-mediated Pluripotency Reprogramming

(2011) Hsiang-Po Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global epigenetic changes during somatic cell reprogramming to iPS cells

(2011) Anna Mattout et al.   Journal of Molecular Cell Biology

Endogenous KLF4 Expression in Human Fetal Endothelial Cells Allows for Reprogramming to Pluripotency With Just OCT3/4 and SOX2—Brief Report

(2010) Pai-Jiun Ho et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Generation of iPSCs from mouse fibroblasts with a single gene, Oct4 and small molecules

(2010) Yanqin Li et al.   CELL RESEARCH

The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells

(2010) Jian-Chien Dominic Heng et al.   Cell Stem Cell

Epithelial Cell Adhesion Molecule Regulation Is Associated with the Maintenance of the Undifferentiated Phenotype of Human Embryonic Stem Cells

(2010) Tung-Ying Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling

(2010) Nadim Maghzal et al.   JOURNAL OF CELL BIOLOGY

Generation of induced pluripotent stem cells from human cord blood cells with only two factors: Oct4 and Sox2

(2010) Alessandra Giorgetti et al.   Nature Protocols

Advances in Reprogramming Somatic Cells to Induced Pluripotent Stem Cells

(2010) Minal Patel et al.   Stem Cell Reviews and Reports

Oct4-Induced Pluripotency in Adult Neural Stem Cells

(2009) Jeong Beom Kim et al.   CELL

A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

(2009) Justin K. Ichida et al.   Cell Stem Cell

Direct reprogramming of human neural stem cells by OCT4

(2009) Jeong Beom Kim et al.   NATURE

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

(2009) Keisuke Kaji et al.   NATURE

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Nuclear signalling by tumour-associated antigen EpCAM

(2009) Dorothea Maetzel et al.   NATURE CELL BIOLOGY

Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells

(2009) Sarah Eminli et al.   NATURE GENETICS

Two Factor Reprogramming of Human Neural Stem Cells into Pluripotency

(2009) Mark E. Hester et al.   PLoS One

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

(2009) Catherine E Forristal et al.   REPRODUCTION

Promising New Sources for Pluripotent Stem Cells

(2009) Christian Leeb et al.   Stem Cell Reviews and Reports

EpCAM Is Involved in Maintenance of the Murine Embryonic Stem Cell Phenotype

(2009) Bárbara González et al.   STEM CELLS

Inhibition of SHP2 leads to mesenchymal to epithelial transition in breast cancer cells

(2008) X-D Zhou et al.   CELL DEATH AND DIFFERENTIATION

c-Myc Is Dispensable for Direct Reprogramming of Mouse Fibroblasts

(2008) Marius Wernig et al.   Cell Stem Cell

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors

(2008) Jeong Beom Kim et al.   NATURE

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Regulation of Sox2 by STAT3 Initiates Commitment to the Neural Precursor Cell Fate

(2008) Kara M. Foshay et al.   STEM CELLS AND DEVELOPMENT