Article
Clinical Neurology
Tuba Maden, Gunseli Usgu, Aysenur Tuncer
Summary: This study compared the viscoelastic properties of the sternocloideomastoideus and masseter muscles between MS patients and healthy individuals. The results showed that the tonus and stiffness of the SCM muscle on the left side were higher in MS patients, which is related to swallowing problems.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2022)
Article
Health Care Sciences & Services
Yerim Do, Prarthana Sanya Lall, Haneul Lee
Summary: The study found that muscle stiffness in older adults was significantly lower than in young adults at rest and during contraction, with both MyotonPRO and SWE being effective tools for assessing muscle function loss associated with aging. Stiffness measures are important for exercise professionals to gain an in-depth understanding of muscle tissue-level damage.
Article
Engineering, Biomedical
Wala Mahmoud, Hans Hultborn, Jagoba Zuluaga, Christoph Zrenner, Brigitte Zrenner, Ulf Ziemann, Ander Ramos-Murguialday
Summary: This study demonstrates that contralesional motor cortex 1 Hz rTMS and physiotherapy can reduce the stretch reflex-mediated component of resistance to muscle stretch without affecting passive stiffness in chronic stroke. No changes were observed in the excitability of the investigated spinal mechanisms.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Article
Health Care Sciences & Services
Heeae Seo, Jeongseon Kim, Changseon Yu, Hyoungwon Lim
Summary: Assessing muscle tone is crucial for the diagnosis, prognosis, and treatment planning of developmental disabilities in children. The myotonometer, an assessment tool used in this study, showed good reliability for measuring muscle tone in children with DD. The intra-rater and inter-rater reliability were excellent, indicating that the myotonometer can objectively assess muscle tone and be used in clinical practice.
Article
Medicine, General & Internal
Youngjin Lee, Minkyoung Kim, Haneul Lee
Summary: The study found moderate to strong correlations between MyotonPRO and SWE measurements of lower limb muscle stiffness during resting and active voluntary contraction. Muscle stiffness was generally higher in men compared to women at rest and during contraction, except for the TA muscle. The instruments showed good intra-rater reliability and moderate to good correlations between measurements at rest and during active voluntary contraction.
Article
Oncology
Yoon Kim, So Yeon An, Won Park, Ji Hye Hwang
Summary: In breast cancer patients undergoing radiotherapy, affected muscles such as the pectoralis major exhibited increased tone, stiffness, and decreased elasticity compared with the unaffected side, persisting four months post-treatment. Changes in muscle properties immediately after radiotherapy preceded subjective stiffness, which worsened significantly four months post-treatment compared with baseline.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Rehabilitation
Megan Banky, Ross A. Clark, Benjamin F. Mentiplay, John H. Olver, Gavin Williams
Summary: Assessing hamstring spasticity at 90 degrees hip flexion resulted in more trials being rated as spastic and with higher severity compared to assessments at 40 degrees hip flexion. The angle of reaction also occurred earlier at 90 degrees hip flexion.
DISABILITY AND REHABILITATION
(2023)
Article
Engineering, Biomedical
Eline Flux, Marjolein M. van der Krogt, Jaap Harlaar, Annemieke Buizer, Lizeth H. Sloot
Summary: This study systematically explored the feasibility, reliability, and validity of sudden treadmill perturbations to provoke and quantify calf muscle stretch reflexes during walking in children with neurological disorders. The protocol's feasibility and reliability were demonstrated, and construct validity was shown from neurophysiological and clinical perspectives by analyzing responses to perturbations. The exaggerated velocity-dependent nature of the measured responses strongly supports the use of treadmill perturbations for quantifying stretch hyperreflexia during gait, providing a framework for informing clinical decision making and treatment evaluation.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Article
Food Science & Technology
Yen-Ting Chen, Yang Liu, Chuan Zhang, Elaine Magat, Ping Zhou, Yingchun Zhang, Sheng Li
Summary: This study aimed to comprehensively assess the effects of Botulinum neurotoxin (BoNT) injection for managing focal spasticity in stroke survivors. The results showed that BoNT injection significantly reduced spasticity, muscle strength, reflex torque, and compound muscle action potential (CMAP) amplitude, and these effects returned to baseline levels after 3 months. Voluntary force control and non-reflex resistance torque were not affected.
Article
Rehabilitation
Gaia Valentina Pennati, Loic Carment, Alison K. Godbolt, Jeanette Plantin, Jorgen Borg, Pavel G. Lindberg
Summary: The study aimed to validate the NeuroFlexor foot module and assess its intra-rater reliability, as well as establish normative cut-off values. Patients with chronic stroke and healthy subjects were examined using the NeuroFlexor at controlled velocities. Results showed that the neural component was higher in stroke patients, increased with stretch velocity, and correlated with electromyography amplitude. Cut-off values were established based on data from healthy subjects. Overall, the NeuroFlexor may provide a feasible and non-invasive method for quantifying lower limb spasticity.
JOURNAL OF REHABILITATION MEDICINE
(2023)
Review
Food Science & Technology
Cemre Su Kaya Keles, Filiz Ates
Summary: Spasticity, a result of cerebral palsy, is characterized by involuntary and prolonged muscle contractions, and can be effectively managed with BTX-A injections. However, recent studies have shown conflicting effects such as increased muscle stiffness or reduced range of active force production. The potential negative effects of these alterations on spastic muscles should be further investigated.
Article
Orthopedics
Dallin C. Swanson, Joshua K. Sponbeck, Derek A. Swanson, Conner D. Stevens, Steven P. Allen, Ulrike H. Mitchell, James D. George, Aaron Wayne Johnson
Summary: The study aimed to investigate the validity and intratester reliability of ultrasound (US) imaging in measuring intrinsic foot muscle size compared to magnetic resonance imaging (MRI). The results showed high correlations and excellent test reliability between US and MRI measurements of intrinsic foot muscle cross-sectional area (CSA).
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Rehabilitation
Stephen A. Ashford, Ajoy Nair, Denise Hancock, Samantha Orridge, Heather Williams, Lynne Turner-Stokes
Summary: The study utilized the Leg Activity Measure for intervention in acquired brain injury spasticity, showing significant improvements in Leg Activity Measure indicators over 12 weeks, particularly in passive function and quality of life aspects.
DISABILITY AND REHABILITATION
(2021)
Article
Clinical Neurology
Jacqueline R. Patterson, Julius P. A. Dewald, Justin M. Drogos, Netta Gurari
Summary: This study aims to investigate how volitional muscle activation impacts stretch reflex activity in individuals with stroke. The results suggest that voluntary muscle activation can nullify the attenuating effect of stretch reflex induced by repeated fast stretches, while resting can sustain the attenuating effect.
FRONTIERS IN NEUROLOGY
(2022)
Article
Cell Biology
Jessica L. Halle, Brittany R. Counts-Franch, Rose M. Prince, James A. Carson
Summary: This study showed that mechanical signaling induced growth stimulus and preserved MyHC-Fast protein expression in myotubes pre-incubated with conditioned media, independent of changes in mRNA expression.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Engineering, Biomedical
Xiaoyan Li, Le Li, Henry Shin, Sheng Li, Ping Zhou
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2017)
Article
Engineering, Biomedical
Xiaoyan Li, Henry Shin, Le Li, Elaine Magat, Sheng Li, Ping Zhou
MEDICAL ENGINEERING & PHYSICS
(2017)
Article
Multidisciplinary Sciences
Henry Shin, Zach Watkins, Xiaogang Hu
SCIENTIFIC REPORTS
(2017)
Article
Clinical Neurology
Sheng Li, Henry Shin, Ping Zhou, Xiaoyan Li
FRONTIERS IN NEUROLOGY
(2017)
Article
Engineering, Biomedical
Henry Shin, Zach Watkins, He (Helen) Huang, Yong Zhu, Xiaogang Hu
JOURNAL OF NEURAL ENGINEERING
(2018)
Article
Engineering, Biomedical
Henry Shin, Nina L. Suresh, William Zev Rymer, Xiaogang Hu
JOURNAL OF NEURAL ENGINEERING
(2018)
Article
Clinical Neurology
Ya Zong, Henry H. Shin, Ying-Chih Wang, Sheng Li, Ping Zhou, Xiaoyan Li
FRONTIERS IN NEUROLOGY
(2018)
Article
Engineering, Biomedical
Henry Shin, Ryan Chen, Xiaogang Hu
JOURNAL OF NEURAL ENGINEERING
(2018)
Article
Engineering, Biomedical
Henry Shin, Xiaogang Hu
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2019)
Article
Engineering, Biomedical
Yang Zheng, Henry Shin, Derek G. Kamper, Xiaogang Hu
Summary: The study proposed a novel framework to detect contracting muscle regions based on the deformation field of transverse ultrasound images. It can capture the activity of muscles at different depths and is not sensitive to muscle shortening during passive movements. This framework could potentially serve as a tool to assess the functions of a group of muscles concurrently.
ANNALS OF BIOMEDICAL ENGINEERING
(2021)
Article
Computer Science, Information Systems
Henry Shin, Marwan A. Hawari, Xiaogang Hu
Summary: This study evaluated an alternative transcutaneous nerve-bundle stimulation method that successfully activated the deep extrinsic finger flexors. The method can produce the full range of motion of different joints necessary for various functional grasps.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2021)
Article
Engineering, Biomedical
Luis Vargas, Henry Shin, He (Helen) Huang, Yong Zhu, Xiaogang Hu
JOURNAL OF NEURAL ENGINEERING
(2020)
Article
Engineering, Biomedical
Xiaoyan Li, Henry Shin, Ya Zong, Sheng Li, Ping Zhou
CLINICAL BIOMECHANICS
(2017)
Article
Clinical Neurology
Le Li, Henry Shin, Argyrios Stampas, Xiaoyan Li, Ping Zhou
CLINICAL NEUROPHYSIOLOGY
(2017)
Article
Rehabilitation
Zhiyuan Lu, Kai-yu Tong, Henry Shin, Argyrios Stampas, Ping Zhou
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2017)