Reduction in Disease Progression by Inhibition of Transforming Growth Factor α-CCL2 Signaling in Experimental Posttraumatic Osteoarthritis

Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation

(2014) B. Staal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disturbed Cartilage and Joint Homeostasis Resulting From a Loss of Mitogen-Inducible Gene 6 in a Mouse Model of Joint Dysfunction

(2014) Michael A. Pest et al.   Arthritis & Rheumatology

Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: An in vitro study

(2013) Quinn Harris et al.   STEM CELLS

Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo

(2013) John B Shepard et al.   ARTHRITIS RESEARCH & THERAPY

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

(2012) Jean-Yves Reginster et al.   ANNALS OF THE RHEUMATIC DISEASES

A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee

(2012) Marie-Pierre Hellio le Graverand et al.   ANNALS OF THE RHEUMATIC DISEASES

Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo

(2012) Annika Burleigh et al.   ARTHRITIS AND RHEUMATISM

Transforming growth factor-alpha induces endothelin receptor A expression in osteoarthritis

(2012) Shirine E. Usmani et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis

(2012) R. E. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a central role for complement in osteoarthritis

(2011) Qian Wang et al.   NATURE MEDICINE

Teriparatide as a Chondroregenerative Therapy for Injury-Induced Osteoarthritis

(2011) E. R. Sampson et al.   Science Translational Medicine

Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis

(2010) David J Hunter et al.   BMC MUSCULOSKELETAL DISORDERS

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9

(2009) Jiang-Hong Gong et al.   CELLULAR IMMUNOLOGY

Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation

(2009) C Thomas G Appleton et al.   LABORATORY INVESTIGATION

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

(2009) Frank Echtermeyer et al.   NATURE MEDICINE

Osteoarthritis in patients with anterior cruciate ligament rupture: A review of risk factors

(2008) Hugues Louboutin et al.   KNEE