Conditional Deletion of the Phd2 Gene in Articular Chondrocytes Accelerates Differentiation and Reduces Articular Cartilage Thickness

Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation

(2016) Shaohong Cheng et al.   ENDOCRINOLOGY

Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage–bone crosstalk

(2016) Steven R. Goldring et al.   Nature Reviews Rheumatology

Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice

(2016) Shaohong Cheng et al.   Scientific Reports

Cdc42 Is Critical for Cartilage Development During Endochondral Ossification

(2015) Wataru Suzuki et al.   ENDOCRINOLOGY

Toward regeneration of articular cartilage

(2015) Masahiro Iwamoto et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Osteoarthritis Pathogenesis: A Review of Molecular Mechanisms

(2014) Bingjiang Xia et al.   CALCIFIED TISSUE INTERNATIONAL

Histochemistry as a unique approach for investigating normal and osteoarthritic cartilage

(2014) G. Musumeci et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Chondrocyte-specific Knockout of Cbfβ Reveals the Indispensable Function of Cbfβ in Chondrocyte Maturation, Growth Plate Development and Trabecular Bone Formation in Mice

(2014) Mengrui Wu et al.   International Journal of Biological Sciences

Conditional Disruption of the Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Defines Its Key Role in Skeletal Development

(2014) Shaohong Cheng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genesis and morphogenesis of limb synovial joints and articular cartilage

(2014) Rebekah S. Decker et al.   MATRIX BIOLOGY

Inactivation ofVhlin Osteochondral Progenitor Cells Causes High Bone Mass Phenotype and Protects Against Age-Related Bone Loss in Adult Mice

(2013) Tujun Weng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cartilage to bone transitions in health and disease

(2013) K A Staines et al.   JOURNAL OF ENDOCRINOLOGY

Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice

(2013) Shaohong Cheng et al.   PHYSIOLOGICAL GENOMICS

Transgenic Overexpression of Ephrin B1 in Bone Cells Promotes Bone Formation and an Anabolic Response to Mechanical Loading in Mice

(2013) Shaohong Cheng et al.   PLoS One

Zone-specific gene expression patterns in articular cartilage

(2012) Shawn P. Grogan et al.   ARTHRITIS AND RHEUMATISM

Articular Cartilage Development: A Molecular Perspective

(2012) Facundo Las Heras et al.   ORTHOPEDIC CLINICS OF NORTH AMERICA

Targeted Disruption of Ephrin B1 in Cells of Myeloid Lineage Increases Osteoclast Differentiation and Bone Resorption in Mice

(2012) Shaohong Cheng et al.   PLoS One

Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?

(2011) P.M. van der Kraan et al.   OSTEOARTHRITIS AND CARTILAGE

Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathway

(2011) Weirong Xing et al.   PHYSIOLOGICAL GENOMICS

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

How does PKMζ maintain long-term memory?

(2010) Todd C. Sacktor   NATURE REVIEWS NEUROSCIENCE

Revealing the interplay of bone and cartilage in osteoarthritis through multimodal imaging of murine joints

(2009) Kathryn S. Stok et al.   BONE

Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

(2009) Christa Maes et al.   EMBO JOURNAL

Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

(2009) Ryan C. Riddle et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Role and regulation of prolyl hydroxylase domain proteins

(2008) G-H Fong et al.   CELL DEATH AND DIFFERENTIATION

PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1  signaling and endoplasmic reticulum stress

(2008) G. Yang et al.   DEVELOPMENT

Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints

(2008) Kolja Gelse et al.   ARTHRITIS RESEARCH & THERAPY

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

(2007) Y. A. Minamishima et al.   BLOOD