Article
Environmental Sciences
Qin Zhou, Xiying Xie, Fengling Feng, Shujian Huang, Yongxue Sun
Summary: The study showed that AHLs may promote microbial reproduction in sediment under florfenicol stress and reduce the effects of antibiotics on the abundance of Nitrospira, thus altering the response of the nitrogen cycle.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Tianli Ma, Cheng Cheng, Lizhen Xing, Yuepeng Sun, Guangxue Wu
Summary: A better understanding of r-/K-strategists nitrifiers is crucial for optimizing the design and operation of bioprocesses for wastewater treatment. This study investigated the nitrite oxidation biokinetics, biofilm properties, microbial community, and quorum sensing (QS) in nitrifying biofilms from a continuously flow reactor (CFR) and a sequencing batch reactor (SBR). The results revealed different nitrite half saturation constants and dominant nitrite-oxidizing taxa in the CFR and SBR. Additionally, the biofilm properties and AHL signaling substances were significantly different between the two reactors. The insights gained from this study provide valuable information on the molecular mechanisms and adaptation of Nitrospira in different biokinetic environments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Immunology
Vivek Kumar Yadav, Pradeep Kumar Singh, Deepmala Sharma, Himanshu Pandey, Sunil Kumar Singh, Vishnu Agarwal
Summary: The AHL molecule 3-oxo-C12 HSL in Pseudomonas aeruginosa induces apoptotic features in human blood platelets, including PS exposure and mitochondrial dysfunction.
MICROBIAL PATHOGENESIS
(2021)
Article
Environmental Sciences
Tianli Ma, Cheng Cheng, Lizhen Xing, Yuepeng Sun, Guangxue Wu
Summary: A better understanding of r-/K-strategists nitrifiers will help to balance the design and operation of bioprocesses for efficient pollution removal from wastewater. The study investigated the biokinetics, biofilm property, microbial community, and quorum sensing (QS) of nitrifying biofilm in a continuously flow reactor (CFR) and a sequencing batch reactor (SBR). Results showed that Nitrospira and Candidatus Nitrospira defluvii were the dominant nitrite-oxidizing taxa in both reactors. The biofilm in SBR had higher ratios of polysaccharide and protein in extracellular polymeric substances and higher thickness compared to CFR. AHLs-based QS might affect the formation of nitrifying biofilm and contribute to the different biokinetics of Nitrospira in CFR and SBR.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Agricultural Engineering
Xiaojing Zhang, Bingbing Ma, Nan Zhang, Han Zhang, Yongpeng Ma, Yali Song, Hongzhong Zhang
Summary: This study investigated the regulatory effect of the external quorum sensing signals, N-dodecanoyl homoserine lactone (C12-HSL), on the CANON process in a membrane bioreactor. C12-HSL enhanced the activity of aerobic ammonia-oxidizing bacteria and improved ammonia monooxygenase activity, while suppressing anaerobic ammonia-oxidizing bacteria and limiting TN removal. Enzyme synthesis was enhanced, enabling the CANON system to resist high C12-HSL concentrations. C12-HSL was found to be profitable for aerobic ammonia oxidation and could be used to regulate nitrite production.
BIORESOURCE TECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Rachith Kalgudi, Roya Tamimi, Godfrey Kyazze, Tajalli Keshavarz
Summary: The study revealed that the combined use of farnesol and tyrosol had a better effect on Pseudomonas aeruginosa biofilm growth, especially against the RBHi strain, while the addition of quorum quenchers (QQs) reduced IL-8 secretion by A549 cells.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Engineering, Environmental
Jing Zhang, Lin-hua Zhang, Peng Sun, Jie-ya He, Jun Li
Summary: This study revealed the crucial role of AHLs in maintaining the stability and activity of Anammox granules at 11-23 degrees C. Exogenous C8-HSL significantly improved granule stability at temperatures of 11-16 degrees C, while C6-HSL and 3OC8-HSL promoted granule activity at temperatures of 11-23 degrees C. This research provides a novel approach to enhance the performance of Anammox granules at low temperatures.
WATER ENVIRONMENT RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Qiang Zhang, Sizhe Li, Maha Hachicha, Mohamed Boukraa, Laurent Soulere, Mohamed L. Efrit, Yves Queneau
Summary: This review summarizes the contribution of heterocyclic chemistry in the design of AHLs analogues, emphasizing how heterocyclic building blocks can serve as replacements of the lactone moiety, as a bioisostere for the amide group, or as an additional pattern appended to the side chain. Additionally, non-AHL-related heterocyclic compounds with AHL-like QS activity are also mentioned.
Article
Engineering, Marine
Gary E. Schultz, Peter H. Santschi
Summary: Free-living bacteria in marine environments are believed to be too sparse to use density-dependent quorum sensing systems. However, this study found that marine bacteria do respond to signal molecules, indicating the presence of quorum sensing in marine gels. This discovery is significant for marine and environmental sciences.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2023)
Article
Agricultural Engineering
Ying Xu, Philip G. Kerr, Jan Dolfing, Bruce E. Rittmann, Yonghong Wu
Summary: This study presents an approach for developing periphytic biofilm with AHLs stimulation and La loading to achieve efficient and stable phosphorus recovery from wastewater. The combination of AHLs stimulation and La loading achieved 99.0% P entrapment and a method for separate recovery of P and La from biofilms was developed.
BIORESOURCE TECHNOLOGY
(2022)
Review
Microbiology
Lanlan Liu, Xiangyong Zeng, Jia Zheng, Yunman Zou, Shuyi Qiu, Yifeng Dai
Summary: This review explores the role of AHL-mediated quorum sensing (AHL-QS) in the regulation of bacterial substance and energy metabolism. The review provides insights into the typical molecular structures, general mechanism, and regulatory mechanisms of AHLs in various metabolic processes.
MICROBIOLOGICAL RESEARCH
(2022)
Article
Engineering, Environmental
Jing Li, He Liu, Ping Wu, Peng Ding, Jie Zhang, Chao Zhang, Bo Fu, Min-hua Cui
Summary: This study investigates the enhancement of caproate production from ethanol and acetate in chain elongation enrichments by utilizing AHLs as signal molecules. The results show that adding C8-HSL significantly increases caproate concentration, possibly due to the increase in protein content and total biomass.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Environmental Sciences
Jie Cheng, Xin Su, Meng Liu, Zhijiang Lu, Jianming Xu, Yan He
Summary: This study investigated the effects of exogenous N-butanoyl homoserine lactone (C4-HSL), N-hexanoyl homoserine lactone (C6-HSL), and 3-oxo-hexanoyl homoserine lactone (3OC6-HSL) on the dechlorination of ?-hexachlorocyclohexane (?) and methane production. The results showed that exogenous C4-HSL and 3OC6-HSL increased cytochrome c production, enriched dechlorinators and electroactive bacteria, and accelerated dechlorination while inhibiting methane production. On the other hand, C6-HSL facilitated dechlorination and methane production by enhancing biofilm electroactivity and increasing membrane transportation.
ENVIRONMENTAL POLLUTION
(2023)
Review
Plant Sciences
Xixian Zhu, Wen-Juan Chen, Kalpana Bhatt, Zhe Zhou, Yaohua Huang, Lian-Hui Zhang, Shaohua Chen, Junxia Wang
Summary: With the increasing resistance of undesirable bacteria to traditional antibiotics, the need to discover alternative treatments is urgent. Quorum sensing is a novel bacterial communication system mediated by signaling molecules called autoinducers. Quorum quenching has been developed as a strategy to inhibit quorum sensing and control resistant bacteria. This review introduces different signaling molecules, elucidates the mechanisms of quorum quenching, and summarizes the applications and advantages of this strategy.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Microbiology
Liushen Lu, Junwei Wang, Ting Qin, Kai Chen, Jun Xie, Bingwen Xi
Summary: In this study, it was found that carvacrol, a natural compound found in plants, can effectively inhibit bacterial communication and reduce the toxicity of pathogenic bacteria. Carvacrol was shown to reduce the production of violacein in Chromobacterium violaceum and the concentration of N-acyl-homoserine lactones (AHLs) in Aeromonas hydrophila NJ-35. These findings suggest that carvacrol could be a potential strategy for reducing the virulence of pathogenic bacteria.
Article
Immunology
Nele de Klerk, Lisa Maudsdotter, Hanna Gebreegziabher, Sunil D. Saroj, Beatrice Eriksson, Olaspers Sara Eriksson, Stefan Roos, Sara Linden, Hong Sjolinder, Ann-Beth Jonsson
INFECTION AND IMMUNITY
(2016)
Article
Microbiology
Sunil D. Saroj, Lisa Maudsdotter, Raquel Tavares, Ann-Beth Jonsson
FRONTIERS IN MICROBIOLOGY
(2016)
Article
Microbiology
Sara Sigurlasdottir, Jakob Engman, Olaspers Sara Eriksson, Sunil D. Saroj, Nadezda Zguna, Pilar Lloris-Garcera, Leopold L. Ilag, Ann-Beth Jonsson
Article
Immunology
Nele de Klerk, Sunil D. Saroj, Gabriela M. Wassing, Lisa Maudsdotter, Ann-Beth Jonsson
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2017)
Article
Biochemistry & Molecular Biology
Yusuke Terui, Sunil D. Saroj, Akihiko Sakamoto, Taketo Yoshida, Kyohei Higashi, Shin Kurihara, Hideyuki Suzuki, Toshihiko Toida, Keiko Kashiwagi, Kazuei Igarashi
Article
Microbiology
Sunil D. Saroj, Katy M. Clemmer, Robert A. Bonomo, Philip N. Rather
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2012)
Article
Microbiology
Sunil D. Saroj, Philip N. Rather
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2013)
Article
Microbiology
Sunil Saroj, R. Shashidhar, Jayant Bandekar
CURRENT MICROBIOLOGY
(2009)
Article
Food Science & Technology
Vandan Nagar, Sachin N. Hajare, Sunil D. Saroj, Jayant R. Bandekar
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2012)
Article
Biochemistry & Molecular Biology
Kyohei Higashi, Yoshiharu Sakamaki, Emiko Herai, Risa Demizu, Takeshi Uemura, Sunil D. Saroj, Risa Zenda, Yusuke Terui, Kazuhiro Nishimura, Toshihiko Toida, Keiko Kashiwagi, Kazuei Igarashi
JOURNAL OF BIOLOGICAL CHEMISTRY
(2010)
Correction
Multidisciplinary Sciences
Timothy R. Sampson, Sunil D. Saroj, Anna C. Llewellyn, Yih-Ling Tzeng, David S. Weiss
Article
Multidisciplinary Sciences
Timothy R. Sampson, Sunil D. Saroj, Anna C. Llewellyn, Yih-Ling Tzeng, David S. Weiss
Correction
Multidisciplinary Sciences
Timothy R. Sampson, Sunil D. Saroj, Anna C. Llewellyn, Yih-Ling Tzeng, David S. Weiss
Review
Microbiology
Rajashri Banerji, Poonam Kanojiya, Sunil D. Saroj
CRITICAL REVIEWS IN MICROBIOLOGY
(2020)
