Pemafibrate, a novel selective peroxisome proliferator-activated receptor alpha modulator, improves the pathogenesis in a rodent model of nonalcoholic steatohepatitis
出版年份 2017 全文链接
标题
Pemafibrate, a novel selective peroxisome proliferator-activated receptor alpha modulator, improves the pathogenesis in a rodent model of nonalcoholic steatohepatitis
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-02-14
DOI
10.1038/srep42477
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial
- (2016) Shun Ishibashi et al. ATHEROSCLEROSIS
- PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis
- (2015) Sven Francque et al. JOURNAL OF HEPATOLOGY
- Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
- (2015) Michal Pawlak et al. JOURNAL OF HEPATOLOGY
- Mitochondrial uncoupling proteins and energy metabolism
- (2015) Rosa A. Busiello et al. Frontiers in Physiology
- Molecular mechanisms of fatty liver in obesity
- (2015) Lixia Gan et al. Frontiers of Medicine
- Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-κB signaling pathway
- (2015) Ning Zhang et al. Oncotarget
- Risk of cardiovascular, cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease
- (2014) Stefano Ballestri WORLD JOURNAL OF GASTROENTEROLOGY
- Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment
- (2013) Jason R. Clapper et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Selective peroxisome proliferator-activated receptorα modulators (SPPARMα): The next generation of peroxisome proliferator-activated receptor α-agonists
- (2013) Jean-Charles Fruchart Cardiovascular Diabetology
- Association betweenUCP3gene polymorphisms and nonalcoholic fatty liver disease in Chinese children
- (2013) Yan-Ping Xu WORLD JOURNAL OF GASTROENTEROLOGY
- Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?
- (2012) Lokpal S. Bhatia et al. EUROPEAN HEART JOURNAL
- Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications
- (2012) Kenneth Cusi GASTROENTEROLOGY
- PPARs: Fatty acid sensors controlling metabolism
- (2012) Lars la Cour Poulsen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Peroxisome Proliferator–Activated Receptor-α Gene Level Differently Affects Lipid Metabolism and Inflammation in Apolipoprotein E2 Knock-In Mice
- (2011) Fanny Lalloyer et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- PPARα activation differently affects microparticle content in atherosclerotic lesions and liver of a mouse model of atherosclerosis and NASH
- (2011) Morgane Baron et al. ATHEROSCLEROSIS
- Roles of PPARs in NAFLD: Potential therapeutic targets
- (2011) Anne Tailleux et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Peroxisome proliferator-activated receptor-α agonist, Wy 14 643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis
- (2011) Claire Z Larter et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- PPARα Expression Protects Male Mice from High Fat–Induced Nonalcoholic Fatty Liver
- (2011) Mohamed A. Abdelmegeed et al. JOURNAL OF NUTRITION
- Molecular basis for gene-specific transactivation by nuclear receptors
- (2010) Mads M. Aagaard et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model
- (2010) Nobuyasu Shindo et al. JOURNAL OF HEPATOLOGY
- UCP3 Expression in Liver Modulates Gene Expression and Oxidative Metabolism in Response to Fatty Acids, and Sensitizes Mitochondria to Permeability Transition
- (2009) Yolanda Camara et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis
- (2009) Kittichai Promrat et al. HEPATOLOGY
- Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis
- (2009) Koji Fujita et al. HEPATOLOGY
- Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice
- (2009) Maaike H. Oosterveer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease
- (2008) C. Fernández-Miranda et al. DIGESTIVE AND LIVER DISEASE
- Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet
- (2008) Mary E. Rinella et al. JOURNAL OF LIPID RESEARCH
- The Epidemiology of Nonalcoholic Fatty Liver Disease: A Global Perspective
- (2008) Mariana Lazo et al. SEMINARS IN LIVER DISEASE
- Fibrates and future PPARα agonists in the treatment of cardiovascular disease
- (2008) Bart Staels et al. Nature clinical practice. Cardiovascular medicine
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started