An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes

Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation

(2016) Mohd Waseem Akhtar et al.   Nature Communications

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

(2015) Jan Marquard et al.   NATURE MEDICINE

Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release

(2015) Ildete Luísa Ferreira et al.   NEUROBIOLOGY OF AGING

NMDA Receptor Antagonist Attenuates Bleomycin-Induced Acute Lung Injury

(2015) Yang Li et al.   PLoS One

Monosodium Glutamate Dietary Consumption Decreases Pancreatic β-Cell Mass in Adult Wistar Rats

(2015) Piyanard Boonnate et al.   PLoS One

Toll-like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes

(2014) Clara Westwell-Roper et al.   IMMUNOLOGY AND CELL BIOLOGY

The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion

(2013) Yun Sok Lee et al.   CELL

Obesity and diabetes related plasma amino acid alterations

(2013) Yong Zhou et al.   CLINICAL BIOCHEMISTRY

The potential role of glutamate in the current diabetes epidemic

(2012) Alberto M. Davalli et al.   ACTA DIABETOLOGICA

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

Inflammation and type 2 diabetes

(2012) M.C. Calle et al.   DIABETES & METABOLISM

Metabolomic Profiling of Fatty Acid and Amino Acid Metabolism in Youth With Obesity and Type 2 Diabetes: Evidence for enhanced mitochondrial oxidation

(2012) S. J. Mihalik et al.   DIABETES CARE

Paracrine Interactions Within Islets of Langerhans

(2012) Duk-Su Koh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The molecular mechanisms of pancreatic β-cell glucotoxicity: Recent findings and future research directions

(2012) Mohammed Bensellam et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Real-time detection of acetylcholine release from the human endocrine pancreas

(2012) Rayner Rodriguez-Diaz et al.   Nature Protocols

Expression of N-methyl D-aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via NF-κB signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats

(2011) Madhuvika Murugan et al.   GLIA

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

(2011) N. Soltani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

(2010) M. Igoillo-Esteve et al.   DIABETOLOGIA

Hypoglycemic and insulin-sensitizing effects of berberine in high-fat diet- and streptozotocin-induced diabetic rats

(2010) Yanwen Wang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Glutamate receptors, neurotoxicity and neurodegeneration

(2010) Anthony Lau et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mitochondrial calcium function and dysfunction in the central nervous system

(2009) David G. Nicholls   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Metabonomic Variations in the Drug-Treated Type 2 Diabetes Mellitus Patients and Healthy Volunteers

(2009) Yuqian Bao et al.   JOURNAL OF PROTEOME RESEARCH

Glutamate Mediates Hyperoxia-Induced Newborn Rat Lung Injury through N-Methyl-D-Aspartate Receptors

(2008) MingJie Wang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Experimental diabetes enhances Ca2+ mobilization and glutamate exocytosis in cerebral synaptosomes from mice

(2008) Eiki Satoh et al.   DIABETES RESEARCH AND CLINICAL PRACTICE