Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

Statin treatment rescues FGFR3 skeletal dysplasia phenotypes

(2014) Akihiro Yamashita et al.   NATURE

Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice

(2014) Jingming Zhou et al.   ARTHRITIS RESEARCH & THERAPY

Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice—a translational model for atherosclerosis

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Lipid Transport and Metabolism in Healthy and Osteoarthritic Cartilage

(2013) Amanda Villalvilla et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study

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RNA extraction from human articular cartilage by chondrocyte isolation

(2012) Shabana Amanda Ali et al.   ANALYTICAL BIOCHEMISTRY

Gene Expression Analyses of Subchondral Bone in Early Experimental Osteoarthritis by Microarray

(2012) RongKai Zhang et al.   PLoS One

Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis

(2012) Fotini Kostopoulou et al.   PLoS One

Statin use is associated with reduced incidence and progression of knee osteoarthritis in the Rotterdam study

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Cholesterol Metabolism Is Required for Intracellular Hedgehog Signal Transduction In Vivo

(2011) Rolf W. Stottmann et al.   PLoS Genetics

Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation

(2010) M. J. Barter et al.   ANNALS OF THE RHEUMATIC DISEASES

Statins: A potential role in the management of osteoarthritis?

(2010) Joseph F. Baker et al.   JOINT BONE SPINE

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis

(2010) C. Karlsson et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Exercise and osteoarthritis

(2009) David J. Hunter et al.   JOURNAL OF ANATOMY

Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-α signalling in endochondral bone growth

(2009) Anita Woods et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

(2008) K. K. Mak et al.   DEVELOPMENT

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols

Multiple roles for lipids in the Hedgehog signalling pathway

(2008) Suzanne Eaton   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sterol regulators of cholesterol homeostasis and beyond: The oxysterol hypothesis revisited and revised

(2008) S GILL et al.   PROGRESS IN LIPID RESEARCH