Promotion of Hypercoagulability in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis by C5a-Induced Tissue Factor-Expressing Microparticles and Neutrophil Extracellular Traps

C5a and TNF-  Up-Regulate the Expression of Tissue Factor in Intra-Alveolar Neutrophils of Patients with the Acute Respiratory Distress Syndrome

(2014) K. Kambas et al.   JOURNAL OF IMMUNOLOGY

Coagulation and Fibrinolysis Index Profile in Patients with ANCA-Associated Vasculitis

(2014) Tian-Tian Ma et al.   PLoS One

Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease

(2013) Konstantinos Kambas et al.   ANNALS OF THE RHEUMATIC DISEASES

C5a Receptor (CD88) Blockade Protects against MPO-ANCA GN

(2013) H. Xiao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Pro-Inflammatory Role of C5L2 in C5a-Primed Neutrophils for ANCA-Induced Activation

(2013) Jian Hao et al.   PLoS One

2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

(2012) J. C. Jennette et al.   ARTHRITIS AND RHEUMATISM

Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies

(2012) T. A. Fuchs et al.   BLOOD

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody–associated vasculitis

(2012) Shen-Ju Gou et al.   KIDNEY INTERNATIONAL

p38MAPK, ERK and PI3K Signaling Pathways Are Involved in C5a-Primed Neutrophils for ANCA-Mediated Activation

(2012) Jian Hao et al.   PLoS One

Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

(2012) Konstantinos Kambas et al.   PLoS One

C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

(2012) Jun Yuan et al.   ARTHRITIS RESEARCH & THERAPY

Pathogenesis of ANCA-Associated Vasculitis

(2012) Rodrigo Cartin-Ceba et al.   Current Rheumatology Reports

Abundant neutrophil extracellular traps in thrombus of patient with microscopic polyangiitis

(2012) Daigo Nakazawa et al.   Frontiers in Immunology

Monocytic microparticles activate endothelial cells in an IL-1 -dependent manner

(2011) J.-G. Wang et al.   BLOOD

Anti-Neutrophil Cytoplasmic Antibodies Stimulate Release of Neutrophil Microparticles

(2011) Y. Hong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters

(2010) B. Gyorgy et al.   BLOOD

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

(2010) K. D. Metzler et al.   BLOOD

Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis

(2010) I. Kourtzelis et al.   BLOOD

Activation of normal neutrophils by anti-neutrophil cytoplasm antibodies

(2010) M. T. KEOGAN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Activation of granulocytes by anti-neutrophil cytoplasmic antibodies (ANCA): a FcγRII-dependent process

(2010) A. H. L. MULDER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The multivalent activity of the tissue factor–thrombin pathway in thrombotic and non-thrombotic disorders as a target for therapeutic intervention

(2010) Ioannis Mitroulis et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoinositol 3-kinase-γ mediates antineutrophil cytoplasmic autoantibody-induced glomerulonephritis

(2009) Adrian Schreiber et al.   KIDNEY INTERNATIONAL

High frequency of venous thromboembolic events in Churg-Strauss syndrome, Wegener's granulomatosis and microscopic polyangiitis but not polyarteritis nodosa: a systematic retrospective study on 1130 patients

(2008) Y Allenbach et al.   ANNALS OF THE RHEUMATIC DISEASES

Complement Activation Is Involved in Renal Damage in Human Antineutrophil Cytoplasmic Autoantibody Associated Pauci-Immune Vasculitis

(2008) Guang-qun Xing et al.   JOURNAL OF CLINICAL IMMUNOLOGY