Article
Multidisciplinary Sciences
Kathryn Hacker, Andrew Z. Greenlee, Alison Hill, Daniel Schneider, Michael Levy, Javaid Iqbal
Summary: Bed bug outbreaks in urban environments have been a major challenge, but interventions implemented by New York City residents and lawmakers have significantly decreased the number of bed bug complaints, potentially serving as a model for other large cities.
Article
Multidisciplinary Sciences
Sudip Gaire, Zachary C. DeVries, Russell Mick, Richard G. Santangelo, Grazia Bottillo, Emanuela Camera, Coby Schal
Summary: Bed bugs are challenging pests to control indoors, with their behavior being influenced by various human skin compounds and environmental factors. Their responses to human skin compounds are multifunctional, with some attracting host-seeking stages and others preventing bed bug arrestment.
SCIENTIFIC REPORTS
(2021)
Article
Entomology
Jaime Strickland, Nicholas R. Larson, Mark Feldlaufer, Aijun Zhang
Summary: The study found that methyl benzoate and its analogs have repellency against bed bugs, with M2MOB and M3MOB exhibiting the strongest repellent effects. With the rise of insecticide resistance, finding effective repellents for bed bugs is becoming increasingly important.
Article
Parasitology
Maria A. Gonzalez-Morales, Andrea E. Thomson, Olivia A. Petritz, Rocio Crespo, Ahmed Haija, Richard G. Santangelo, Coby Schal
Summary: The common bed bug, once a pest in poultry farms, has been reappearing causing potential health issues to chickens. This study found that systemic antiparasitic drugs used on chickens can effectively control bed bug infestations, demonstrating the efficacy of fluralaner as a potent new active ingredient for bed bug control.
PARASITES & VECTORS
(2022)
Editorial Material
Parasitology
Jan Stefka, Jan Votypka, Julius Lukes, Ondrej Balvin
Summary: Bed bugs are blood-feeding insects that have made a comeback in the past two decades due to insecticide resistance and increased human mobility.
TRENDS IN PARASITOLOGY
(2022)
Article
Entomology
Jutamas Kerdsawang, Kai Dang, Theeraphap Chareonviriyaphap, Stephen L. Doggett
Summary: There has been a worldwide resurgence in bed bug populations over the past two decades, primarily due to insecticide resistance. Researchers have found that lethal harborages, especially those impregnated with silica dioxide, offer a cost-effective solution that could be incorporated into broader integrated bed bug management strategies.
Article
Entomology
Maria A. Gonzalez-Morales, Zachary DeVries, Angela Sierras, Richard G. Santangelo, Madhavi L. Kakumanu, Coby Schal
Summary: Bed bug populations globally exhibit resistance to pyrethroids and neonicotinoids, necessitating the discovery of new active ingredients with different modes of action. Fipronil has shown high efficacy against bed bugs, but resistance mechanisms involve detoxification enzymes such as cytochrome P450s and esterases. Inhibition of these enzymes can reverse fipronil resistance, with populations also showing cross-resistance to deltamethrin. Understanding the origins of fipronil resistance is crucial for developing new active ingredients and integrated pest management strategies.
JOURNAL OF MEDICAL ENTOMOLOGY
(2021)
Article
Evolutionary Biology
Chloe Haberkorn, Jean-Philippe David, Helene Henri, Jean-Marie Delpuech, Romain Lasseur, Fabrice Vavre, Julien Varaldi
Summary: In the last few years, the bed bug Cimex lectularius has become a growing problem worldwide due to resistance to pyrethroids. A study compared the genetic composition of recent resistant populations with ancient-susceptible strains to identify variants associated with resistance. A large superlocus containing clustered resistance genes and structural variants was identified, suggesting the possibility of a resistance supergene that evolved after allele clustering and reduced recombination.
EVOLUTIONARY APPLICATIONS
(2023)
Article
Parasitology
Maria A. Gonzalez-Morales, Andrea E. Thomson, James Yeatts, Hiroko Enomoto, Ahmed Haija, Richard G. Santangelo, Olivia A. Petritz, Rocio Crespo, Coby Schal, Ronald Baynes
Summary: Bed bug infestations are re-emerging in the poultry industry, causing adverse effects on bird health and welfare. Fluralaner has shown promising results in controlling these pests, with a treatment effect lasting for at least 28 days.
PARASITES & VECTORS
(2023)
Article
Entomology
Bjorn Arne Rukke, Espen Roligheten, Anders Aak
Summary: This study highlights the importance of elevating the competence of low-income housing owners in pest management for controlling bed bug infestations. By implementing integrated pest management strategies and maintaining strong buyer-supplier relations, it is possible to achieve efficient eradication at a reduced cost.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Entomology
Cari D. Lewis, Brenna A. Levine, Coby Schal, Edward L. Vargo, Warren Booth
Summary: Over the past decade, the continuous use of pyrethroid insecticides has resulted in a significant increase in knockdown-associated insecticide resistance (kdr) mutations in bed bugs. The presence of multiple kdr mutations in recent infestations suggests that strong selection pressure has driven the rapid evolution of adaptive traits in bed bug populations.
JOURNAL OF PEST SCIENCE
(2023)
Article
Agronomy
Anders Aak, Morten Hage, Bjorn Arne Rukke
Summary: This study conducted forced exposure experiments with different formulations, doses, and substrates on bed bugs in variable physiological states. The results showed that both oil and water-formulated fungal products had significant improvement in efficacy with increased conidial concentrations. Substrate, dosage, application strategy, bed bug age, and reproductive status were all important factors that affected the effectiveness of Beauveria bassiana in controlling bed bugs.
PEST MANAGEMENT SCIENCE
(2023)
Article
Entomology
Chow-Yang Lee, Changlu Wang, Nan-Yao Su
Summary: Bed bugs are important medical and urban pests that preferentially infest low socioeconomic communities. Despite progress in research and control strategies, infestations in poor communities continue to be a reservoir for wider society. This collection of research papers explores bed bug detection, insecticide performance and resistance, nonchemical treatment, and pest management procurement and contracts, aiming to inspire future research on safer, more affordable, and effective control options.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2023)
Article
Multidisciplinary Sciences
Ahmed M. Saveer, Zachary C. DeVries, Richard G. Santangelo, Coby Schal
Summary: Reproductive fitness and survival in female bed bugs are influenced by mating status, starvation period, and social interactions. Mated females showed a higher feeding rate and blood intake compared to unmated females, and their response to human skin odor was also more pronounced. Additionally, frequent copulation attempts decreased survivorship and lifespan in females.
SCIENTIFIC REPORTS
(2021)
Article
Entomology
Morgan M. Wilson, Dini M. Miller
Summary: This study quantified the fecal spot production of bed bugs at different nymphal stages and adult stage. It was found that clear spots were produced in greater amounts compared to dark or light spots. The collected data allowed researchers to project contamination potential and the area covered by fecal spots.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Multidisciplinary Sciences
Yue Gao, Suning Liu, Qiangqiang Jia, Lixian Wu, Dongwei Yuan, Emma Y. Li, Qili Feng, Guirong Wang, Subba R. Palli, Jian Wang, Sheng Li
Summary: The study reveals that JH membrane signaling phosphorylates USP at Ser35 through PKC activation, enhancing the regulation of 20E on fruit fly development. The uspS35A mutant with Ala substitution at Ser35 shows reduced body size and delayed developmental timing.
Article
Entomology
Xien Chen, Subba Reddy Palli
Summary: The study identified the molecular mechanism of deltamethrin resistance in fall armyworm by showing the key role of P450 gene SfCYP321A8, which could be applied in resistance and functional genomics research. Transgenic lines expressing P450 genes were developed and showed significantly increased tolerance to deltamethrin through bioassays, highlighting the potential for further research on insecticide resistance in lepidopteran pests.
JOURNAL OF PEST SCIENCE
(2022)
Article
Entomology
Xien Chen, Subba Reddy Palli
Summary: A piggyBac-based germline transformation system was established in the fall armyworm, Spodoptera frugiperda, a global agricultural pest. Tissue-specific promoters were identified and used to drive the expression of transgenes, resulting in tissue-specific overexpression. Overexpression of certain genes in the midgut was found to confer insecticide resistance.
JOURNAL OF PEST SCIENCE
(2023)
Article
Agriculture, Multidisciplinary
Ramesh Kumar Dhandapani, Dhandapani Gurusamy, Subba Reddy Palli
Summary: This study evaluated a nanoparticle delivery system based on protamine sulfate (PS)/lipid/dsRNA for gene silencing in the fall armyworm and demonstrated its high efficiency and stability in cells and larvae.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Sharath Chandra Gaddelapati, Najla M. Albishi, Ramesh Kumar Dhandapani, Subba Reddy Palli
Summary: This study identified 10 genes coding for HDACs in the yellow fever mosquito and determined their role in larval development using RNA interference. The findings suggest that HDAC3 plays a crucial role in larval development and knockdown of HDAC3 leads to larval death and affects midgut size.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Infectious Diseases
Anna R. Pasternak, Subba R. Palli
Summary: Lyme disease, the most common tick-borne illness in the United States, is increasing in prevalence each year. A study conducted in Kentucky, a non-endemic area, revealed a more than 300% increase in reported human cases from 2010 to 2019. Monitoring the distribution of infected ticks is crucial for effective prevention strategies and disease surveillance.
TICKS AND TICK-BORNE DISEASES
(2022)
Article
Entomology
Xien Chen, Subba Reddy Palli
Summary: This study reports the establishment of multiple transgenic CRISPR/Cas9-based genome editing methods in the global agricultural pest, fall armyworm, Spodoptera frugiperda. Fluorescent proteins suitable for screening for transgenic fall armyworm were identified. The use of U6-tRNA-sgRNA system for sgRNA expression was found to be more efficient in inducing target gene knockout. These methods provide valuable tools for gene editing and functional genomics studies in the fall armyworm and other lepidopteran pests.
JOURNAL OF PEST SCIENCE
(2023)
Editorial Material
Agronomy
Yulin Gao, Andrei Alyokhin, Ralf Nauen, Raul N. C. Guedes, Subba Reddy Palli
PEST MANAGEMENT SCIENCE
(2022)
Article
Genetics & Heredity
Guang-Hua Luo, Xi-En Chen, Yao-Yu Jiao, Guan-Heng Zhu, Ru Zhang, Ramesh Kumar Dhandapani, Ji-Chao Fang, Subba Reddy Palli
Summary: This study reveals that the SoxC gene plays a crucial role in the regulation of insect ecdysis, and is associated with the expression of neuropeptide genes such as EH.
FRONTIERS IN GENETICS
(2022)
Review
Entomology
Marc Kenis, Giovanni Benelli, Antonio Biondi, Paul-Andre Calatayud, Roger Day, Nicolas Desneux, Rhett D. Harrison, Darren Kriticos, Ivan Rwomushana, Johnnie van den Berg, Francois Verheggen, Yong-Jun Zhang, Lakpo Koku Agboyi, Regis Besmer Ahissou, Malick N. Ba, Julio Bernal, Adeney de Freitas Bueno, Yves Carriere, Geraldo Andrade Carvalho, Xue-Xin Chen, Lizette Cicero, Hannalene du Plessis, Regan Early, Patrick Fallet, Komi K. M. Fiaboe, Dnyaneshwar M. Firake, Georg Goergen, Astrid T. Groot, Raul N. C. Guedes, Ankita Gupta, Gao Hu, Fn Huang, Lara R. Jaber, Edi A. Malo, Christina B. McCarthy, Robert L. Meagher, Samira Mohamed, David Mota Sanchez, Rodney N. Nagoshi, Nicolas Negre, Saliou Niassy, Noboru Ota, Casper Nyamukondiwa, Celso Omoto, Subba Reddy Palli, Roman Pavela, Ricardo Ramirez-Romero, Julio C. Rojas, Sevgan Subramanian, Bruce E. Tabashnik, Wee Tek Tay, Eduardo Gabriel Virla, Su Wang, Trevor Williams, Lian-Sheng Zang, Lisheng Zhang, Kongming Wu
Summary: This article provides a comprehensive review of the fall armyworm, including its biology, worldwide status and spread, management strategies, and recommendations for sustainable management in invaded regions.
ENTOMOLOGIA GENERALIS
(2023)
Article
Agronomy
Xingeng Wang, Jessica Faucher, Ramesh Kumar Dhandapani, Jian J. Duan, Subba Reddy Palli
Summary: This study investigated the impact of dsRNA-based insecticides on the survival and behavior of a parasitoid wasp. The results showed that direct injection of dsRNA did not affect the wasp's survival, but it indirectly affected the suitability and detectability of host larvae.
PEST MANAGEMENT SCIENCE
(2023)
Article
Infectious Diseases
Anna R. Pasternak, Subba R. Palli
Summary: Kentucky experiences a high incidence of ehrlichiosis, primarily transmitted by the lone star tick. Surveillance of tick distribution and pathogen detection is crucial for monitoring the expansion of this important tick vector and the increase in tick-borne diseases.
TICKS AND TICK-BORNE DISEASES
(2023)
Article
Multidisciplinary Sciences
Heng Jiang, Xiangkun Meng, Nan Zhang, Huichen Ge, Jiaping Wei, Kun Qian, Yang Zheng, Yoonseong Park, Subba Reddy Palli, Jianjun Wang
Summary: This study found that deltamethrin-induced oxidative stress activates AMPK, promoting the nuclear translocation of CncC through phosphorylation. CncC acts as a transcription activator of detoxification genes and regulates the expression of genes involved in ecdysteroid biosynthesis and juvenile hormone degradation. This results in increased ecdysteroid levels, decreased juvenile hormone titer, and down-regulated vitellogenin gene expression.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biochemistry & Molecular Biology
Jinmo Koo, Dhandapani Gurusamy, Subba Reddy Palli
Summary: There is limited success in using exogenous small interfering RNA (siRNA) or small hairpin RNA (shRNA) to trigger RNA interference (RNAi) in insects. Instead, long double-stranded RNA (dsRNA) is used to induce gene knockdown in insects. In this study, the potency of si/sh RNAs and dsRNA was compared in Colorado potato beetle (CPB) cells. CPB cells showed a highly efficient RNAi response to dsRNA, but si/sh RNAs were inefficient in triggering RNAi in CPB cells.
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yaoyu Jiao, Subba Reddy Palli
Summary: m6A methylation is a common modification of mRNA, which regulates multiple stages of mRNA processing. In this study, the role of m6A modification in insect development was explored using the red flour beetle as a model. Knockdown of m6A writers and readers disrupted ecdysis during eclosion, sterilized the insects, and affected egg laying and embryonic development.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2023)