Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney

Improvement of cardiovascular remodelling by chymase inhibitor

(2016) Shinji Takai et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout Mice

(2016) Yi-Han Hung et al.   International Journal of Biological Sciences

A new class of drugs for systolic heart failure: The PARADIGM-HF study

(2015) M. A. SABE et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction

(2015) Adriaan A. Voors et al.   EUROPEAN JOURNAL OF HEART FAILURE

Antagonism of angiotensin 1–7 prevents the therapeutic effects of recombinant human ACE2

(2015) Vaibhav B. Patel et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Pharmacodynamic effects of C-domain-specific ACE inhibitors on the renin-angiotensin system in myocardial infarcted rats

(2015) Sarah Sharp et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Angiotensin(1–7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade

(2015) Kai Zhang et al.   KIDNEY INTERNATIONAL

Optimum AT1 receptor-neprilysin inhibition has superior cardioprotective effects compared with AT1 receptor blockade alone in hypertensive rats

(2015) Lodi C.W. Roksnoer et al.   KIDNEY INTERNATIONAL

Role of non-classical renin-angiotensin system axis in renal fibrosis

(2015) Lin-Li Lv et al.   Frontiers in Physiology

The ACE2/Apelin Signaling, MicroRNAs, and Hypertension

(2015) Lai-Jiang Chen et al.   International Journal of Hypertension

Blood Pressure, Hypertension, RAAS Blockade, and Drug Therapy in Diabetic Kidney Disease

(2014) Hala Yamout et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Reduced plasma angiotensin II levels are reversed by hydroxyurea treatment in mice with sickle cell disease

(2014) Alisson F. dos Santos et al.   LIFE SCIENCES

Molecular regulation of the renin–angiotensin system in haemodialysis patients

(2014) Johannes J. Kovarik et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Prolyl Carboxypeptidase Activity Decline Correlates with Severity and Short-Term Outcome in Acute Ischemic Stroke

(2014) Kaat Kehoe et al.   NEUROCHEMICAL RESEARCH

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

(2014) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry

(2013) Nadja Grobe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Estimation of angiotensin peptides in biological samples by LC–MS method

(2013) Quaisar Ali et al.   Analytical Methods

Co-morbidities in patients with heart failure: an analysis of the European Heart Failure Pilot Survey

(2013) Vincent M. van Deursen et al.   EUROPEAN JOURNAL OF HEART FAILURE

Mass spectrometry for the molecular imaging of angiotensin metabolism in kidney

(2012) Nadja Grobe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Loss of Angiotensin-Converting Enzyme-2 Exacerbates Diabetic Cardiovascular Complications and Leads to Systolic and Vascular Dysfunction

(2012) Vaibhav B. Patel et al.   CIRCULATION RESEARCH

The effect of antihypertensive drugs on chronic kidney disease: a comprehensive review

(2012) Anastasia G Ptinopoulou et al.   HYPERTENSION RESEARCH

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

Angiotensin II Infusion Induces Marked Diaphragmatic Skeletal Muscle Atrophy

(2012) Bashir M. Rezk et al.   PLoS One

Regulation of angiotensin-(1–7) and angiotensin II type 1 receptor by telmisartan and losartan in adriamycin-induced rat heart failure

(2011) Wen-na Zong et al.   ACTA PHARMACOLOGICA SINICA

Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

(2010) Merlin C. Thomas et al.   CIRCULATION RESEARCH

Epidemiology of hypertensive kidney disease

(2010) Suneel Udani et al.   Nature Reviews Nephrology

Physiology of Kidney Renin

(2010) Hayo Castrop et al.   PHYSIOLOGICAL REVIEWS

Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension

(2009) Anderson J. Ferreira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

(2009) G. Y. Oudit et al.   DIABETES

Angiotensin I Is Largely Converted to Angiotensin (1-7) and Angiotensin (2-10) by Isolated Rat Glomeruli

(2009) Juan Carlos Q. Velez et al.   HYPERTENSION

Angiotensin-converting enzyme 2 gene targeting studies in mice: mixed messages

(2008) Susan B. Gurley et al.   EXPERIMENTAL PHYSIOLOGY

Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart

(2008) Paul J. Garabelli et al.   EXPERIMENTAL PHYSIOLOGY