In Vivo Characterization of ARN14140, a Memantine/Galantamine-Based Multi-Target Compound for Alzheimer’s Disease

Protection by sigma-1 receptor agonists is synergic with donepezil, but not with memantine, in a mouse model of amyloid-induced memory impairments

(2016) Tangui Maurice   BEHAVIOURAL BRAIN RESEARCH

Biomarkers of lipid peroxidation in Alzheimer disease (AD): an update

(2015) Melissa A. Bradley-Whitman et al.   ARCHIVES OF TOXICOLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Polypharmacology: the rise of multitarget drugs over combination therapies

(2014) Michela Rosini   Future Medicinal Chemistry

Multi-target Design Strategies in the Context of Alzheimer’s Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces

(2014) Michela Rosini et al.   NEUROCHEMICAL RESEARCH

2013 Alzheimer's disease facts and figures

(2013)   Alzheimers & Dementia

Oxidative Stress in Alzheimer’s Disease: Are We Connecting the Dots?

(2013) Michela Rosini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease

(2013) Valentine Lahmy et al.   NEUROPSYCHOPHARMACOLOGY

Memantine and Cholinesterase Inhibitors: Complementary Mechanisms in the Treatment of Alzheimer’s Disease

(2013) Chris G. Parsons et al.   NEUROTOXICITY RESEARCH

Alzheimer's Disease Related Markers, Cellular Toxicity and Behavioral Deficits Induced Six Weeks after Oligomeric Amyloid-β Peptide Injection in Rats

(2013) Charleine Zussy et al.   PLoS One

Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity

(2013) João P. Lopes et al.   Brain and Behavior

The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1–42 seeding and short-term memory deficits in the Aβ25–35 mouse model of Alzheimer's disease

(2012) Johann Meunier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Combining Galantamine and Memantine in Multitargeted, New Chemical Entities Potentially Useful in Alzheimer’s Disease

(2012) Elena Simoni et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synergistic Effects of Galantamine and Memantine in Attenuating Scopolamine-Induced Amnesia in Mice

(2012) Perrine Busquet et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Time-Course and Regional Analyses of the Physiopathological Changes Induced after Cerebral Injection of an Amyloid β Fragment in Rats

(2011) Charleine Zussy et al.   AMERICAN JOURNAL OF PATHOLOGY

Alzheimer's Disease: Redox Dysregulation As a Common Denominator for Diverse Pathogenic Mechanisms

(2011) Rommy von Bernhardi et al.   ANTIOXIDANTS & REDOX SIGNALING

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses

(2010) P. Xia et al.   JOURNAL OF NEUROSCIENCE

Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative

(2010) Vanessa Villard et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ25–35

(2009) Yury G. Kaminsky et al.   EXPERIMENTAL NEUROLOGY

Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

(2008) Andrea Cavalli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antiamnesic and Neuroprotective Effects of the Aminotetrahydrofuran Derivative ANAVEX1-41 Against Amyloid β25–35-Induced Toxicity in Mice

(2008) Vanessa Villard et al.   NEUROPSYCHOPHARMACOLOGY

The anti-amnesic and neuroprotective effects of donepezil against amyloid β25-35 peptide-induced toxicity in mice involve an interaction with the σ1 receptor

(2006) J Meunier et al.   BRITISH JOURNAL OF PHARMACOLOGY