Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding

Fasted/fed states regulate postsynaptic hub protein DYNLL2 and glutamatergic transmission in oxytocin neurons in the hypothalamic paraventricular nucleus

(2016) Shigetomo Suyama et al.   NEUROPEPTIDES

Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding behavior through glucose-inhibited neurons

(2015) Hideharu Kurita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Interplay between glucose and leptin signalling determines the strength of GABAergic synapses at POMC neurons

(2015) Dong Kun Lee et al.   Nature Communications

Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

(2014) Jian Qiu et al.   Cell Metabolism

Central Adiponectin Acutely Improves Glucose Tolerance in Male Mice

(2014) Christiane E. Koch et al.   ENDOCRINOLOGY

AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels

(2014) D. Grahame Hardie et al.   PHYSIOLOGY

Adiponectin receptors: A review of their structure, function and how they work

(2013) Toshimasa Yamauchi et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Adiponectin Regulates Bone Mass via Opposite Central and Peripheral Mechanisms through FoxO1

(2013) Daisuke Kajimura et al.   Cell Metabolism

p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake

(2012) Yossi Dagon et al.   Cell Metabolism

PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake

(2010) Kristy Iskandar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adiponectin Modulates Excitability of Rat Paraventricular Nucleus Neurons by Differential Modulation of Potassium Currents

(2010) Ted D. Hoyda et al.   ENDOCRINOLOGY

Leptin Excites Proopiomelanocortin Neurons via Activation of TRPC Channels

(2010) J. Qiu et al.   JOURNAL OF NEUROSCIENCE

Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1

(2010) Masato Iwabu et al.   NATURE

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

(2009) Hind Al-Qassab et al.   Cell Metabolism

Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases

(2009) T Yamauchi et al.   INTERNATIONAL JOURNAL OF OBESITY

The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

(2009) Leona Plum et al.   NATURE MEDICINE

Adiponectin acts in the nucleus of the solitary tract to decrease blood pressure by modulating the excitability of neuropeptide Y neurons

(2008) Ted D. Hoyda et al.   BRAIN RESEARCH

PDK1 Deficiency in POMC-Expressing Cells Reveals FOXO1-Dependent and -Independent Pathways in Control of Energy Homeostasis and Stress Response

(2008) Bengt F. Belgardt et al.   Cell Metabolism

Adiponectin Depolarizes Parvocellular Paraventricular Nucleus Neurons Controlling Neuroendocrine and Autonomic Function

(2008) Ted Donald Hoyda et al.   ENDOCRINOLOGY

AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus

(2008) Andressa Coope et al.   FEBS LETTERS

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice

(2008) Jennifer W. Hill et al.   JOURNAL OF CLINICAL INVESTIGATION

Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons

(2008) E Guillod-Maximin et al.   JOURNAL OF ENDOCRINOLOGY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL