Age-related impairment of humoral response to influenza is associated with changes in antigen specific T follicular helper cell responses

Defective TFH Cell Function and Increased TFR Cells Contribute to Defective Antibody Production in Aging

(2015) Peter T. Sage et al.   Cell Reports

ICOS, CD40, and Lymphotoxin   Receptors Signal Sequentially and Interdependently to Initiate a Germinal Center Reaction

(2014) F. Vu et al.   JOURNAL OF IMMUNOLOGY

Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation

(2014) C. S. Lages et al.   JOURNAL OF IMMUNOLOGY

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility

(2013) Heping Xu et al.   NATURE

The aged microenvironment contributes to the age-related functional defects of CD4 T cells in mice

(2012) Julie S. Lefebvre et al.   AGING CELL

Expansion of follicular helper T cells in the absence of Treg cells: Implications for loss of B-cell anergy

(2012) Steven M. Leonardo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Receptor Ly108 Functions as a SAP Adaptor-Dependent On-Off Switch for T Cell Help to B Cells and NKT Cell Development

(2012) Robin Kageyama et al.   IMMUNITY

Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation

(2012) André Ballesteros-Tato et al.   IMMUNITY

The origins, function, and regulation of T follicular helper cells

(2012) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

(2011) Youn Soo Choi et al.   IMMUNITY

Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone

(2011) Steven M. Kerfoot et al.   IMMUNITY

Quantity, not quality, of antibody response decreased in the elderly

(2011) Bonnie B. Blomberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells

(2011) I. Wollenberg et al.   JOURNAL OF IMMUNOLOGY

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84

(2010) Jennifer L. Cannons et al.   IMMUNITY

Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)

(2010) I. Yusuf et al.   JOURNAL OF IMMUNOLOGY

Effects of aging on B cell function

(2009) Daniela Frasca et al.   CURRENT OPINION IN IMMUNOLOGY

Age-associated up-regulation of a negative co-stimulatory receptor PD-1 in mouse CD4+ T cells

(2009) Yukiko Shimada et al.   EXPERIMENTAL GERONTOLOGY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Migration of immature and mature B cells in the aged microenvironment

(2009) Heather A. Minges Wols et al.   IMMUNOLOGY

Proinflammatory Adjuvants Enhance the Cognate Helper Activity of Aged CD4 T Cells

(2009) Alexander C. Maue et al.   JOURNAL OF IMMUNOLOGY

Advancing age leads to predominance of inhibitory receptor expressing CD4 T cells☆

(2009) Rudragouda Channappanavar et al.   MECHANISMS OF AGEING AND DEVELOPMENT

T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses

(2008) Cecile King et al.   Annual Review of Immunology

SAP-controlled T–B cell interactions underlie germinal centre formation

(2008) Hai Qi et al.   NATURE