The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKL

The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers

(2015) S T Kundu et al.   ONCOGENE

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

(2014) C. P. Bracken et al.   EMBO JOURNAL

ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism

(2014) Yanan Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

(2014) Janna K Mouw et al.   NATURE MEDICINE

A pan-cancer proteomic perspective on The Cancer Genome Atlas

(2014) Rehan Akbani et al.   Nature Communications

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

(2014) Limo Chen et al.   Nature Communications

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways

(2013) X Li et al.   ONCOGENE

The role of epithelial–mesenchymal transition programming in invasion and metastasis: a clinical perspective

(2013) Chad Creighton et al.   Cancer Management and Research

A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model

(2012) B. J. Gill et al.   CANCER RESEARCH

ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression

(2012) Young-Ho Ahn et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of crkl correlates with poor prognosis and cell proliferation in non-small cell lung cancer

(2012) Yan Wang et al.   MOLECULAR CARCINOGENESIS

CrkL is not Crk-like

(2012) Yoshihiro Kobashigawa et al.   Nature Chemical Biology

Targets of the Tumor Suppressor miR-200 in Regulation of the Epithelial-Mesenchymal Transition in Cancer

(2011) M. J. Schliekelman et al.   CANCER RESEARCH

MicroRNAs as regulators of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   CELL CYCLE

The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200–dependent pathway in mice

(2011) Yanan Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms by Which the Extracellular Matrix and Integrin Signaling Act to Regulate the Switch Between Tumor Suppression and Tumor Promotion

(2011) Patricia J. Keely   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

MicroRNA-200c Represses Migration and Invasion of Breast Cancer Cells by Targeting Actin-Regulatory Proteins FHOD1 and PPM1F

(2011) S. Jurmeister et al.   MOLECULAR AND CELLULAR BIOLOGY

Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers

(2011) H. W. Cheung et al.   Cancer Discovery

MicroRNAs in malignant progression

(2010) Li Ma et al.   CELL CYCLE

Loss of miR-200c Expression Induces an Aggressive, Invasive, and Chemoresistant Phenotype in Non-Small Cell Lung Cancer

(2010) P. Ceppi et al.   MOLECULAR CANCER RESEARCH

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

(2009) D. L. Gibbons et al.   GENES & DEVELOPMENT

A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer

(2009) Xiaoxia Hu et al.   GYNECOLOGIC ONCOLOGY

Down-regulation of miR-141 in gastric cancer and its involvement in cell growth

(2009) Ying Du et al.   JOURNAL OF GASTROENTEROLOGY

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer

(2009) Y H Kim et al.   ONCOGENE

Expression Signatures of Metastatic Capacity in a Genetic Mouse Model of Lung Adenocarcinoma

(2009) Don L. Gibbons et al.   PLoS One

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Phosphatidylinositol 3-Kinase Mediates Bronchioalveolar Stem Cell Expansion in Mouse Models of Oncogenic K-ras-Induced Lung Cancer

(2008) Yanan Yang et al.   PLoS One