Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide

Molecular mechanisms of protein aggregation from global fitting of kinetic models

(2016) Georg Meisl et al.   Nature Protocols

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Peculiar Role of the A2V Mutation in Amyloid-β (Aβ) 1–42 Molecular Assembly

(2014) Massimo Messa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Surface Effects on Aggregation Kinetics of Amyloidogenic Peptides

(2014) Robert Vácha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

(2014) Georg Meisl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution conditions determine the relative importance of nucleation and growth processes in  -synuclein aggregation

(2014) A. K. Buell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay

(2013) Paolo Arosio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity

(2013) Luisa Diomede et al.   NEUROBIOLOGY OF DISEASE

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Aromatic Side Chains in Amyloid β-Protein Aggregation

(2012) Risto Cukalevski et al.   ACS Chemical Neuroscience

From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation

(2012) Samuel I.A. Cohen et al.   JOURNAL OF MOLECULAR BIOLOGY

A Mobile Precursor Determines Amyloid-β Peptide Fibril Formation at Interfaces

(2012) Lei Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations

(2011) Samuel I. A. Cohen et al.   JOURNAL OF CHEMICAL PHYSICS

Dual Effect of Amino Modified Polystyrene Nanoparticles on Amyloid β Protein Fibrillation

(2010) Celia Cabaleiro-Lago et al.   ACS Chemical Neuroscience

Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features

(2010) Giorgio Giaccone et al.   ACTA NEUROPATHOLOGICA

Critical role of interfaces and agitation on the nucleation of Aβ amyloid fibrils at low concentrations of Aβ monomers

(2010) Akiyoshi Morinaga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species

(2010) Asad Jan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid β-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process

(2009) Erik Hellstrand et al.   ACS Chemical Neuroscience

A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide

(2009) Dominic M. Walsh et al.   FEBS Journal

The Recombinant Amyloid-β Peptide Aβ1–42 Aggregates Faster and Is More Neurotoxic than Synthetic Aβ1–42

(2009) Verena H. Finder et al.   JOURNAL OF MOLECULAR BIOLOGY

A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis

(2009) G. Di Fede et al.   SCIENCE

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Inhibition of Amyloid β Protein Fibrillation by Polymeric Nanoparticles

(2008) Celia Cabaleiro-Lago et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY