WP1066 Sensitizes Oral Squamous Cell Carcinoma Cells to Cisplatin by Targeting STAT3/miR-21 axis

The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis

(2015) Qing Chang et al.   NEOPLASIA

Abrogation of constitutive Stat3 activity circumvents cisplatin resistant ovarian cancer

(2013) Teng Ji et al.   CANCER LETTERS

Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells

(2013) Uri Rozovski et al.   Molecular Cancer

Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma

(2013) Yunbao Pan et al.   PLoS One

miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN

(2013) Shou-mei Yang et al.   TOXICOLOGY

MiR-21 Modulates hTERT Through a STAT3-Dependent Manner on Glioblastoma Cell Growth

(2012) Ying-Yi Wang et al.   CNS Neuroscience & Therapeutics

Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells

(2011) Huan-Chih Chiu et al.   BIOCHEMICAL PHARMACOLOGY

miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP

(2011) Wei Zhu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells

(2011) L Y W Bourguignon et al.   ONCOGENE

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

(2010) Yu Ren et al.   BMC CANCER

IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines

(2010) Wiltrud Lederle et al.   INTERNATIONAL JOURNAL OF CANCER

Co-delivery of as-miR-21 and 5-FU by Poly(amidoamine) Dendrimer Attenuates Human Glioma Cell Growth in Vitro

(2010) Yu Ren et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Changes in Survival in Head and Neck Cancers in the Late 20th and Early 21st Century: A Period Analysis

(2010) D. Pulte et al.   ONCOLOGIST

Tat-BMPs-PAMAM Conjugates Enhance Therapeutic Effect of Small Interference RNA on U251 Glioma Cells In Vitro and In Vivo

(2009) Lei Han et al.   HUMAN GENE THERAPY