Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells

Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2

(2013) Jie Sun et al.   Nature Communications

Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions

(2012) Olivier Rossier et al.   NATURE CELL BIOLOGY

SLK-mediated phosphorylation of paxillin is required for focal adhesion turnover and cell migration

(2012) J L Quizi et al.   ONCOGENE

Principles and Strategies for Developing Network Models in Cancer

(2011) Dana Pe'er et al.   CELL

Mechanisms of integrin activation and trafficking

(2011) Coert Margadant et al.   CURRENT OPINION IN CELL BIOLOGY

Imaging the coordination of multiple signalling activities in living cells

(2011) Christopher M. Welch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells

(2011) Shaoying Lu et al.   PLoS One

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells

(2009) Y Xu et al.   BRITISH JOURNAL OF CANCER

Visualization of Src Activity at Different Compartments of the Plasma Membrane by FRET Imaging

(2009) Jihye Seong et al.   CHEMISTRY & BIOLOGY

Dynamics and Variability of ERK2 Response to EGF in Individual Living Cells

(2009) Cellina Cohen-Saidon et al.   MOLECULAR CELL

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stoichiometry of molecular complexes at adhesions in living cells

(2009) M. A. Digman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescence Proteins, Live-Cell Imaging, and Mechanobiology: Seeing Is Believing

(2008) Yingxiao Wang et al.   Annual Review of Biomedical Engineering

Visualization of Polarized Membrane Type 1 Matrix Metalloproteinase Activity in Live Cells by Fluorescence Resonance Energy Transfer Imaging

(2008) Mingxing Ouyang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites

(2008) A. Efimov et al.   JOURNAL OF CELL SCIENCE

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors

(2008) M. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Proteomics of Individual Cancer Cells in Response to a Drug

(2008) A. A. Cohen et al.   SCIENCE

The Spatiotemporal Pattern of Src Activation at Lipid Rafts Revealed by Diffusion-Corrected FRET Imaging

(2008) Shaoying Lu et al.   PLoS Computational Biology