Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization

X-ray structure of the mouse serotonin 5-HT3 receptor

(2014) Ghérici Hassaine et al.   NATURE

Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments

(2014) Sibel Kalyoncu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

(2012) Aaron A. Thompson et al.   NATURE

N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor

(2012) Yaozhong Zou et al.   PLoS One

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

(2012) W. Liu et al.   SCIENCE

Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis

(2012) James W. Fairman et al.   STRUCTURE

Crystallization chaperone strategies for membrane proteins

(2011) Raquel L. Lieberman et al.   METHODS

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragment

(2011) J. A. Piccirilli et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

High-Efficiency Screening of Monoclonal Antibodies for Membrane Protein Crystallography

(2011) Hyun-Ho Lim et al.   PLoS One

Conversion of scFv peptide-binding specificity for crystal chaperone development

(2011) J. C. Pai et al.   PROTEIN ENGINEERING DESIGN & SELECTION

An approach to crystallizing proteins by metal-mediated synthetic symmetrization

(2011) Arthur Laganowsky et al.   PROTEIN SCIENCE

Wnt Antagonists Bind through a Short Peptide to the First β-Propeller Domain of LRP5/6

(2011) Eric Bourhis et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CHOBIMALT: A Cholesterol-Based Detergent

(2010) Stanley C. Howell et al.   BIOCHEMISTRY

A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination

(2010) Yelena Koldobskaya et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

Lipopeptide detergents for membrane protein studies

(2009) Gilbert G Privé   CURRENT OPINION IN STRUCTURAL BIOLOGY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

In Situ Proteolysis to Generate Crystals for Structure Determination: An Update

(2009) Amy Wernimont et al.   PLoS One

Crystal structure of full-length KcsA in its closed conformation

(2009) S. Uysal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CHAINSAW: a program for mutating pdb files used as templates in molecular replacement

(2008) Norman Stein   JOURNAL OF APPLIED CRYSTALLOGRAPHY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Toward chaperone-assisted crystallography: Protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold

(2008) Valentina Tereshko et al.   PROTEIN SCIENCE

Chaperone-Assisted Crystallography with DARPins

(2008) Gaby Sennhauser et al.   STRUCTURE