Structures of yeast peroxisomal Δ3,Δ2-enoyl-CoA isomerase complexed with acyl-CoA substrate analogues: the importance of hydrogen-bond networks for the reactivity of the catalytic base and the oxyanion hole

Human Δ3,Δ2-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10

(2015) Goodluck U. Onwukwe et al.   FEBS Journal

Using Unnatural Amino Acids to Probe the Energetics of Oxyanion Hole Hydrogen Bonds in the Ketosteroid Isomerase Active Site

(2014) Aditya Natarajan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Extreme electric fields power catalysis in the active site of ketosteroid isomerase

(2014) Stephen D. Fried et al.   SCIENCE

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Specificity in Transition State Binding: The Pauling Model Revisited

(2013) Tina L. Amyes et al.   BIOCHEMISTRY

Identification and characterization of Eci3, a murine kidney-specific Δ3,Δ2-enoyl-CoA isomerase

(2013) Michel van Weeghel et al.   FASEB JOURNAL

The isomerase and hydratase reaction mechanism of the crotonase active site of the multifunctional enzyme (type-1), as deduced from structures of complexes with 3S-hydroxy-acyl-CoA

(2013) Prasad Kasaragod et al.   FEBS Journal

Stereoselective preparation of lipidated carboxymethyl-proline/pipecolic acid derivatives via coupling of engineered crotonases with an alkylmalonyl-CoA synthetase

(2013) Refaat B. Hamed et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Functional redundancy of mitochondrial enoyl-CoA isomerases in the oxidation of unsaturated fatty acids

(2012) Michel van Weeghel et al.   FASEB JOURNAL

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Peroxisomal multifunctional enzyme type 2 from the fruitfly: dehydrogenase and hydratase act as separate entities, as revealed by structure and kinetics

(2011) Tatu J. K. Haataja et al.   BIOCHEMICAL JOURNAL

Stereoelectronic Requirements for Optimal Hydrogen-Bond-Catalyzed Enolization

(2011) Imre Pápai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

(2011) Refaat B. Hamed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective C–C bond formation catalysed by engineered carboxymethylproline synthases

(2011) Refaat B. Hamed et al.   Nature Chemistry

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles

(2010) Refaat B. Hamed et al.   CHEMICAL COMMUNICATIONS

Crystal Structure of Liganded Rat Peroxisomal Multifunctional Enzyme Type 1

(2010) Prasad Kasaragod et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On Catalytic Preorganization in Oxyanion Holes: Highlighting the Problems with the Gas-Phase Modeling of Oxyanion Holes and Illustrating the Need for Complete Enzyme Models

(2010) Shina C. L. Kamerlin et al.   JOURNAL OF ORGANIC CHEMISTRY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Mechanisms and structures of crotonase superfamily enzymes – How nature controls enolate and oxyanion reactivity

(2008) R. B. Hamed et al.   CELLULAR AND MOLECULAR LIFE SCIENCES