4.6 Article

Kurahyne, an acetylene-containing lipopeptide from a marine cyanobacterial assemblage of Lyngbya sp.

期刊

RSC ADVANCES
卷 4, 期 25, 页码 12840-12843

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra00132j

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  1. Ministry of Education, Culture, Sports, Science and Technology of Japan [24310160, 25750386]
  2. Ministry of Education, Culture, Sports, Science and Technology, Japan
  3. Grants-in-Aid for Scientific Research [25750386] Funding Source: KAKEN

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Kurahyne, a new acetylene-containing lipopeptide, was isolated from a cyanobacterial assemblage that mostly consisted of Lyngbya sp. Its structure was elucidated by spectroscopic analyses and chiral HPLC analyses of hydrolysis products. Kurahyne inhibited the growth of human cancer cells and induced apoptosis in HeLa cells, and it seemed to localize in mitochondria.

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