Article
Chemistry, Multidisciplinary
Weixu Lu, Xiaoqiang Yu, Ming Bao
Summary: In this paper, a group of copper-based ternary deep eutectic solvents (Cu-DESs) were synthesized and applied in Glaser-type homo- and cross-coupling of terminal alkynes. These reactions occurred under exogenous-ligand-free, base-free, and additive-free conditions, providing satisfactory to excellent yields (up to 99%) under mild conditions. The Cu-DESs can be recycled eight times, with water being the only by-product, complying fully with the principles of green chemistry.
Article
Chemistry, Multidisciplinary
Mandana Oloub, Rahman Hosseinzadeh, Mahmood Tajbakhsh, Maryam Mohadjerani
Summary: A water-soluble fluorescent sensor based on CPBA was designed and synthesized, which exhibited selective fluorescent response to glucose in the pH range of 4-10. The selectivity of CPBA towards glucose was achieved through aggregation-induced emission (AIE) phenomenon, indicating high affinity for glucose.
Article
Chemistry, Multidisciplinary
Julio Zamora-Moreno, Maria K. Salomon-Flores, Josue Valdes-Garcia, Cristian Pinzon-Vanegas, Diego Martinez-Otero, Joaquin Barroso-Flores, Raul Villamil-Ramos, Miguel A. Romero-Solano, Alejandro Dorazco-Gonzalez
Summary: A new dicationic diboronic acid receptor capable of fluorescent recognition of saccharides in pure water has been synthesized and studied. The receptor shows high affinity and selectivity towards sorbitol, demonstrating its potential application in analytical sciences and biological chemistry.
Article
Engineering, Environmental
Udayakumar Veerabagu, Zhaobin Chen, Jiao Xiang, Zihua Chen, Mingen Liu, Hong Xia, Fushen Lu
Summary: A novel Pd@carbon composite derived from cigarette butts was successfully prepared and exhibited improved dispersion and stability of Pd nanoparticles for the Suzuki-Miyaura cross-coupling reaction. The work not only addresses environmental concerns but also offers insights into the valorization of high-performance carbon nanomaterials at low cost and in large quantities.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Inorganic & Nuclear
Ivan J. Bazany-Rodriguez, Maria K. Salomon-Flores, Alejandro O. Viviano-Posadas, Marco A. Garcia-Eleno, Joaquin Barroso-Flores, Diego Martinez-Otero, Alejandro Dorazco-Gonzalez
Summary: The new fluorescent Zn(ii)-terpyridine complexes are effective chemosensors for catecholamine-based neurotransmitters and nucleosides in water, showing high affinity and selectivity, with a blue emission that is quenched by the addition of l-DOPA and other compounds. The proposed binding mode between the Zn(ii)-chemosensors and l-DOPA involves a two-point recognition mechanism, including reversible esterification and coordination, as supported by multiple spectroscopic techniques and crystal structures.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Multidisciplinary
Marina Rajadurai, E. Ramanjaneya Reddy
Summary: Compound 1.1 is a novel fluorescent chemosensor with highly selective detection ability for Hg2+, showing at least 7 times improvement in sensitivity towards Hg2+ in the presence of d-fructose, a result of cooperative binding.
Review
Chemistry, Inorganic & Nuclear
Ji-Ting Hou, Nahyun Kwon, Shan Wang, Bingya Wang, Xiaojun He, Juyoung Yoon, Jianliang Shen
Summary: Hypochlorous acid is an endogenously produced reactive oxygen species that plays a crucial role in various diseases. Sulfur-based fluorescent probes for HOCl have shown excellent performance in terms of rapid reaction rate, high selectivity, and sensitivity, which are essential for better understanding the role of HOCl in chemical biology.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Nanoscience & Nanotechnology
Xueyan Sun, Shaofeng Li, Jinzhe Cao, Yuchao Wang, Wenbo Yang, Lijing Zhang, Yijin Liu, Jieshan Qiu, Shengyang Tao
Summary: The integration of catalytic production and separation of biphenyl (with a purity of 99.7%) was successfully achieved by combining Suzuki cross-coupling reactions and crystallization separation. A hierarchical-structured impeller loaded with Pd nanoparticles on Ni(OH)(2) nanosheets catalyzed the reactions with high turnover frequency (TOF) value of 25,976 h(-1) and a yield of 99.5%. X-ray absorption fine structure (XAFS) analysis revealed that enhanced catalytic activity was due to electron transfer between the Pd nanoparticles and Ni(OH)(2).
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Khaoula Oudghiri, Lahoucine Bahsis, Said Eddarir, Hafid Anane, Moha Taourirte
Summary: A green protocol for the in situ synthesis of Pd nanoparticles on chitosan beads (Pd NPs-CS) without toxic reducing agents was reported. The Pd nanoparticles catalyst was prepared by a simple coordination reaction between chitosan beads and palladium ions. The Pd NPs-CS catalyst showed high catalytic activity and selectivity in Suzuki-Miyaura cross-coupling reaction and Heck reaction, with the bead form of the catalyst easily separated from the reaction mixture.
Article
Chemistry, Organic
Danish Khan, Iram Parveen
Summary: A new family of phosphine-free Amino-chroman-4-one bidentate ligands were successfully synthesised and characterised, showing efficient catalytic activity in C-C bond formation. They demonstrated excellent performance in Suzuki-Miyaura and Mizoroki-Heck coupling reactions, with a broad range of substrates well tolerated under the optimized reaction conditions. Mass spectrometry was used to characterize the metal complex and intermediates formed in the catalytic cycle, supporting the reaction mechanism.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Review
Chemistry, Inorganic & Nuclear
Partha Roy
Summary: DFP is an important fluorophoric platform for the development of chemosensors with high selectivity and sensitivity. Compounds based on DFP can detect various metal ions, anions, neutral molecules, and pH ranges, offering a wide range of applications. The field of DFP-based chemosensors is emerging with plenty of opportunities for further research and development.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Anindita Dewan, Manashi Sarmah, Prantika Bhattacharjee, Pankaj Bharali, Ashim J. Thakur, Utpal Bora
Summary: This study reports the design, synthesis, and application of naturally occurring cellulose from agro waste pomegranate peel as a novel support for active biogenic Pd nanoparticles for Suzuki-Miyaura and Sonogashira cross-coupling reactions at room temperature. The cellulose matrix enables well dispersion of Pd nanoparticles over the support to generate Pd@cellulose, exhibiting excellent catalytic activity and recyclability under ligand-free mild reaction conditions. The synthesized cellulose nanofibers and Pd-anchored heterogeneous nanofibers were characterized through various analytical techniques.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2021)
Review
Chemistry, Physical
Gianluigi Albano, Antonella Petri, Laura Antonella Aronica
Summary: In recent years, there has been extensive research on immobilizing palladium nanoparticles on solid supports for the preparation of active and stable catalytic systems. Compared to inorganic materials, naturally occurring organic solids are more cost-effective and readily available. This review focuses on the application of metal catalysts supported by natural biomaterials in C-C bond formation reactions, specifically Mizoroki-Heck, Suzuki-Miyaura, and Sonogashira reactions. Different types of organic matrices, such as cellulose, starch, pectin, agarose, chitosan, as well as proteins and enzymes, are discussed, highlighting the heterogeneous nature and recyclability of each catalyst.
Article
Chemistry, Physical
Seongsoo Kim, Seohyeon Jee, Kyung Min Choi, Dong-Sik Shin
Summary: This study successfully achieved efficient Suzuki-Miyaura cross coupling reactions in aqueous media by designing discrete cages of metal-organic polyhedra anchoring single Pd atoms. The structure showed high stability and recyclability, making it a promising candidate for single-atom catalysis applications in water.
Article
Chemistry, Multidisciplinary
Dan-Xia Zhao, Guo-Ping Lu, Chun Cai
Summary: The development of a Co and Ce-doped BiOCl and Bi2O2CO3 composite material has shown high photocatalytic activity under white LED irradiation, allowing for efficient platinum-promoted coupling reactions at room temperature with a high yield.
Review
Chemistry, Multidisciplinary
Wen-Qi Meng, Adam C. Sedgwick, Nahyun Kwon, Mingxue Sun, Kai Xiao, Xiao-Peng He, Eric Anslyn, Tony D. James, Juyoung Yoon
Summary: Chemical warfare agents (CWAs) are targeted toxic chemicals that pose serious threats to public health and global peace. Accurate detection methods for CWAs are essential for security measures. Small molecule fluorescent probes have emerged as attractive tools for CWA detection due to their simplicity, selectivity, and sensitivity, and their ability to be translated into handheld devices.
CHEMICAL SOCIETY REVIEWS
(2023)
Review
Chemistry, Multidisciplinary
Hai-Hao Han, Han-Min Wang, Paramesh Jangili, Mingle Li, Luling Wu, Yi Zang, Adam C. Sedgwick, Jia Li, Xiao-Peng He, Tony D. James, Jong Seung Kim
Summary: Cancer is a major global health problem, with millions of people diagnosed each year. Current chemotherapy options lack selectivity for cancer cells, are prone to resistance, and have toxicities. Researchers have focused on developing prodrug-based strategies to overcome these limitations. This review discusses recently developed prodrug strategies for cancer therapy and highlights the importance of targeting specific biomarkers in the tumor microenvironment and overexpressed in cancer cells. The advantages and limitations of each approach are also discussed.
CHEMICAL SOCIETY REVIEWS
(2023)
Editorial Material
Chemistry, Multidisciplinary
Run Zhang, Tony D. James
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Review
Chemistry, Inorganic & Nuclear
Min Ge, Shouxin Liu, Jian Li, Meng Li, Shujun Li, Tony D. James, Zhijun Chen
Summary: Luminescent materials have great potential in various fields, and the conversion of biomass resources into functional luminescent materials has gained significant attention. However, only a few reviews have focused on this area. This review aims to address this gap and introduce the types of biomass sources available for the preparation of luminescent materials. It will cover the structure-optical performance correlation, preparation and optical properties, potential applications, and future challenges and perspectives of biomass-derived luminescent materials.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Chemistry, Analytical
Si-Lin Xu, Fang-Fang Guo, Zhi-Hong Xu, Yuan Wang, Tony D. James
Summary: A water-soluble fluorescent probe 1 based on chromene-hemicyanine has been developed, which exhibits colorimetric fluorescent response towards hypochlorite (ClO-) with a low LOD (0.082 mu M), and turn-on response to viscosity changes. Due to its low cytotoxicity and good biocompatibility, probe 1 is used to monitor hypochlorous acid and viscosity in mitochondria of living cells and zebrafish.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Multidisciplinary Sciences
Yingxiang Zhai, Shujun Li, Jian Li, Shouxin Liu, Tony D. James, Jonathan L. Sessler, Zhijun Chen
Summary: By treating natural wood with magnesium chloride, it can be converted into a viable room temperature phosphorescence (RTP) material called C-wood. C-wood exhibits intense RTP emission and can be used to create afterglow wood sculptures and printable afterglow fibers for luminescent plastics via 3D printing.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Peng Zhang, Xuechuan Wang, Xiao Wang, Chusen Huang, Tony D. James, Xiaolong Sun, Xuhong Qian
Summary: This research developed small molecule-based fluorescent probes for chemoselective labeling of vicinal dithiol-containing proteins (VDPs) in live cells, allowing the study of intracellular redox homeostasis. The probes achieved selective labeling of VDPs through thiol-thiol substitutions on bisvinylogous thioester conjugated acceptors (IDAs). The probes demonstrated high sensitivity, low limit of detection, and selectivity for labeling vicinal dithiols on reduced bovine serum albumin, as well as successfully labeling endogenous VDPs at different redox states in live cells.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yujie Geng, Hanchen Zhang, Guoyang Zhang, Jiaying Zhou, Mingguang Zhu, Lijun Ma, Xuefei Wang, Tony D. D. James, Zhuo Wang
Summary: Schizophrenia is a common mental disorder with unclear mechanisms. This research developed a near-infrared fluorescent probe for noninvasive detection of endogenous superoxide anion (O-2 (-)) in the brain, providing direct evidence for the relationship between oxidative stress, neuroinflammation, and schizophrenia. Furthermore, the study confirmed the burst of O-2(-) in the brains of first-episode schizophrenic mice and assessed the effect of two atypical antipsychotic drugs on redox homeostasis.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Meng Li, Quanyu Shi, Ningxin Song, Yumeng Xiao, Lidong Wang, Zhijun Chen, Tony D. James
Summary: The shortage of freshwater resources caused by heavy metal pollution is a global issue that greatly impacts environmental protection and human health. Developing innovative and cost-effective materials for detecting and removing heavy metal ions is crucial.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Organic
Yiming Zhao, Fernanda Meloni, Louise Male, Cecile S. Le Duff, William D. G. Brittain, Benjamin R. Buckley, John S. Fossey
Summary: The synthesis of atropisomeric phoshino-triazoles is described. Phosphine introduction at the 5-position of a 1,2,3-triazole ring restricts rotation around a triazole-aryl bond. VT NMR and chiral HPLC studies confirm the conformational stability at high temperatures. Gold(i) chloride complexes of single-enantiomer phosphines also show conformational stability.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Review
Chemistry, Multidisciplinary
Huiyu Niu, Junwei Liu, Helen M. O'Connor, Thorfinnur Gunnlaugsson, Tony D. James, Hua Zhang
Summary: Typical PeT-based fluorescent probes are multi-component systems that utilize a fluorophore connected to a recognition/activating group through an unconjugated linker. These probes have been widely used in cell imaging and disease diagnosis due to their low background fluorescence and significant fluorescence enhancement towards the target. This review summarizes the research progress made in the past five years on PeT-based fluorescent probes targeting cell polarity, pH, and various biological species, emphasizing molecular design strategies, mechanisms, and applications. By providing guidance and promoting the development of new and improved PeT-based fluorescent probes, this review aims to promote the use of PeT-based systems for sensing, imaging, and disease therapy.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Ruixia Liu, Hongda Guo, Mengnan Cao, Ben Dang, Yingxiang Zhai, Shouxin Liu, Shujun Li, Jian Li, Tony D. James, Zhijun Chen
Summary: An efficient top-down method is developed for processing natural wood into RTP films with a lifetime of approximate to 241.9 ms. The treated wood is converted into W-film with good tensile strength, triggering RTP emission and exhibiting energy transfer properties with Rhodamine B. This research is expected to provide a convenient and sustainable method for preparing RTP films.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Fei Cheng, Taotao Qiang, Mingli Li, Tony D. James
Summary: A novel zinc diporphyrin molecular graphene Oligo-Zn-Por photocatalyst was synthesized and showed high Cr(vi) reduction efficiency and cycling ability under sunlight.
CATALYSIS SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Kai-Cheng Yan, Jordan E. E. Gardiner, Adam C. C. Sedgwick, Naing Thet, Rachel A. A. Heylen, Tony D. D. James, A. Toby A. Jenkins, Xiao-Peng He
Summary: A new fluorescent probe was developed to determine the NTR activity of different bacterial species under various growth conditions, which can be applied in complex clinical environments with high sensitivity and detection accuracy for both planktonic cultures and biofilms.
CHEMICAL COMMUNICATIONS
(2023)
