Article
Chemistry, Inorganic & Nuclear
Mohammed Dahmani, Tarik Harit, Abdelkader Et-touhami, Abderrahmane Yahyi, Driss Eddike, Monique Tillard, Redouane Benabbes
Summary: Two new organotin (IV) bipyrazole-dicarboxylate macrocyclic complexes, C1 and C2, were synthesized and characterized using various spectroscopic techniques. The complexes showed higher antifungal activity against Fusarium oxysporum f. sp. albedinis compared to the corresponding ligands, indicating their potential as fungicidal agents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Xue Chen, He Wang, Jiajun Wang, Lu Zhao, Chuanbi Li, Chunling Liu
Summary: Two complexes were synthesized and characterized, with one forming a layered structure through hydrogen bonds and the other containing two independent subunits with C- H⋅⋅⋅O hydrogen bonds. Fluorescent properties showed different emission peaks, and the UV-absorption peak decreased with time under illumination conditions, with one complex being more effective than the other in photocatalytic reactions.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Inorganic & Nuclear
Isabel Abanades Lazaro, Ross S. Forgan, Francisco. G. Cirujano
Summary: The influence of composition and textural characteristics of ultra-small isoreticular UiO-type metal-organic frameworks (MOFs) on catalytic performance is evaluated in this study. The activity of Zr-MOF nanoparticles is tested using two different amide bond formation reactions as proof-of-concept. The results provide insights into the catalytic mechanism and optimal properties for enhancing performance.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Organic
Jessica M. L. Elwood, Martyr C. Henry, J. Daniel Lopez-Fernandez, Jenna M. Mowat, Mhairi Boyle, Benjamin Buist, Keith Livingstone, Craig Jamieson
Summary: We have reported the use of N-2,4-dinitrophenyltetrazoles as latent active esters (LAEs) in the synthesis of amide bonds. This method allows the generation of an HOBt-type active ester without the need for exogenous coupling agents. The methodology is applicable to a wide range of substrates, providing quantitative yields. The versatility and functional group tolerance were demonstrated in the one-step synthesis of various pharmaceutical agents and the N-acylation of resin-bound peptides.
Article
Chemistry, Physical
Jun-Fei Gu, Cheng Chen, Zhong-Hui Zheng, Jing Hang, Wei Sang, Ji-Chao Wang, Ye Yuan, Somboon Chaemchuen, Francis Verpoort
Summary: In this study, it was found that ZIF-8, a representative Zn-based metal-organic framework, exhibits high porosity, good stability, and large surface area. ZIF-8 shows promising potential in catalyzing the acceptorless dehydrogenation of alcohols to carboxylates and demonstrates good reusability. Additionally, KOH plays a crucial role in this catalytic process.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Physical
Shuxian Yu, Chuan Li, Shuhua Fan, Juan Wang, Lu Liang, Min Hong
Summary: Three new organotin(IV) complexes have been synthesized by reacting organotin(IV) chlorides with Schiff base carboxylic acid ligand. The complexes were characterized and evaluated for their structural features and cytotoxicities. The results showed that the di-n-butyltin(IV) and triphenyltin(IV) complexes exhibited higher cytotoxicities, possibly due to the generation of intracellular reactive oxygen species (ROS).
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Organic
Yiping Li, Jingyue Li, Guangjun Bao, Changjun Yu, Yuyang Liu, Zeyuan He, Peng Wang, Wen Ma, Junqiu Xie, Wangsheng Sun, Rui Wang
Summary: In this study, a novel coupling reagent NDTP was explored, which exhibited mild, nonirritating, convenient availability, and recyclability. It could activate carboxylic acids via acyl thiocyanide and enable the rapid synthesis of amides and peptides under mild conditions. Furthermore, the methodology was compatible with Fmoc-SPPS, providing an alternative approach for peptide manufacturing.
Article
Chemistry, Organic
Christopher R. Opie, Hidetoshi Noda, Masakatsu Shibasaki, Naoya Kumagai
Summary: This Letter describes the design, synthesis, and evaluation of the first isolable N(BOH)2 compound as an amidation catalyst. The new catalyst outperforms the previously reported B3NO2 heterocycle catalyst, with respect to turnover frequency, albeit the former gradually decomposes upon exposure to amines. This work opens up an avenue for designing a better catalyst for direct amidation.
Article
Chemistry, Physical
Xiu-Zhi Wei, Fentahun Wondu Dagnaw, Jianguo Liu, Longlong Ma
Summary: This article introduces a method to convert alcohols into carboxylic acids using NH2-MIL-125(Ti)/NaBr catalytic system and demonstrates the efficient and highly selective oxidation activity of this photocatalytic system.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Multidisciplinary Sciences
Michael Winn, Michael Rowlinson, Fanghua Wang, Luis Bering, Daniel Francis, Colin Levy, Jason Micklefield
Summary: Coronatine and related bacterial phytotoxins mimic plant hormone JA-Ile and disrupt important plant physiological signaling pathways. The enzyme CfaL can synthesize JA-Ile and a variety of amides, showing potential for applications in agrochemicals and pharmaceuticals.
Article
Chemistry, Physical
Tariq Ali, Niaz Muhammad, Zafar Ali, Abdus Samad, Mohammad Ibrahim, Muhammad Ikram, Sadia Rehman, Shaukat Shujah, Gul Shahzada Khan, Abdul Wadood, Saqib Ali, Carola Schulzke
Summary: Triorganotin(IV) carboxylate complexes were synthesized and characterized by various techniques, revealing different coordination numbers of the tin ion in solid state and solution, as well as the significant impact of the coordination mode on antioxidant activity. Molecular docking studies suggested possible interactions of the complexes with DNA and active sites of certain proteins.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Materials Science, Multidisciplinary
Priyanka Dhankhar, Rekha Devi, Sushma Devi, Sangeeta Chahar, Mandeep Dalal, V. B. Taxak, S. P. Khatkar, Priti Boora
Summary: Five novel europium(III) complexes with different ancillary ligands were synthesized and their photoluminescent properties and thermal stability were investigated. The complexes exhibited characteristic red emission of Eu3+ metal ion with high color purity and were found suitable for fabrication of OLEDs devices.
Article
Pharmacology & Pharmacy
Niaz Muhammad, Mukhtar Ahmad, Muhammad Sirajuddin, Zafar Ali, Nikolay Tumanov, Johan Wouters, Abdelbasset Chafik, Kuebra Solak, Ahmet Mavi, Shabbir Muhammad, Shaukat Shujah, Saqib Ali, Abdullah G. Al-Sehemi
Summary: In this study, four new carboxylates complexes were synthesized and their structures and properties were investigated. The results showed that these complexes exhibited different coordination modes and high activity, and displayed dose-dependent cytotoxic effects on lung cancer cells. Molecular docking analysis also demonstrated significant interactions between these complexes and DNA, tubulin, and coronaviruses proteins.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Lingjian Zi, Jing Zhang
Summary: We describe a method for iron-catalyzed amide bond formation using readily available carboxylic acids and isocyanates. This method utilizes an abundant and biocompatible iron catalyst and accessible starting materials, generates only CO2 as a byproduct, and has a broad substrate scope with good functional group compatibility. Therefore, it provides a cost-effective and practical protocol to access a diverse variety of amides.
CHINESE JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Hua Zhou, Zhenhua Li, Si-Min Xu, Lilin Lu, Ming Xu, Kaiyue Ji, Ruixiang Ge, Yifan Yan, Lina Ma, Xianggui Kong, Lirong Zheng, Haohong Duan
Summary: The study presents an efficient electrochemical strategy for upgrading lignin derivatives to carboxylates using MnCoOOH catalyst, with yields of 80-99% and operational stability up to 200 hours. A tandem oxidation mechanism is revealed, allowing for effective transformation of lignin derivatives into carboxylates.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
