Article
Chemistry, Physical
Nitish Deshpande, Jee-Yee Chen, Takeshi Kobayashi, Eun Hyun Cho, Hannah Pineault, Li -Chiang Lin, Nicholas A. Brunelli
Summary: This study investigates the impact of micropores on the catalytic activity of aminosilica materials. By comparing materials with micropores and materials with negligible micropore volume, it is found that the materials with negligible micropore volume exhibit higher catalytic activity in a range of reactions.
JOURNAL OF CATALYSIS
(2022)
Article
Engineering, Environmental
Celine Demeese, Clara Lods, David-Alexandre Buisson, Edmond Gravel, Irishi N. N. Namboothiri, Eric Doris
Summary: A proline analog assembled on carbon nanotubes was utilized as a heterogenized catalyst in asymmetric aldol reactions, showing high efficiency, good enantioselectivity, and sustainability using pure water as the solvent. The catalyst operates with low loadings and can be recycled without loss of performance, resulting in aldol products with yields up to 99% and enantiomeric excesses up to 98%.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Yingzhe Yu, Hai Chen, Yantao Hu, Minhua Zhang
Summary: Density functional theory was used to investigate the transition states and energy barriers of side reactions of Aldol condensation on MgO(1 0 0) and MgO(1 1 0) surfaces. The results showed different formation mechanisms of acetone on different crystal planes of MgO, while ethoxyethanol formation reaction had higher activity on both surfaces. Comparing the energy barriers and reaction heats, it was found that the side reactions are more likely to occur on the MgO(1 0 0) surface in terms of kinetics and thermodynamics.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Physical
Shashikant A. Kadam, Andrew Hwang, Enrique Iglesia
Summary: This study investigates the effects of non-polar liquids on acetone aldol condensation reactions on TiO2 surfaces. The results show that non-polar liquids enhance reaction rates and selectivity by stabilizing transition states for adsorption and desorption. Additionally, solvation by non-polar liquids prevents the formation of larger oligomers, leading to slower deactivation of the catalyst.
Article
Chemistry, Physical
Fangliang Li, Binli Wang, Xiao Chen, Hongjun Fan, Xueming Yang, Qing Guo
Summary: The study shows that the R-TiO2(100)-(1 x 1) surface exhibits high reactivity and selectivity for aldol condensation of unbranched aldehydes at room temperature. The low energy barriers for enolization and dehydration reactions, along with stable adsorption of intermediates, contribute to the surface's efficiency in forming crotonaldehyde. The exclusive selectivity of (E)-crotonaldehyde formation is attributed to the adsorption configuration of CH3CHO and surface structure of R-TiO2(100)(1 x 1).
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Wen-Lei Xu, Wei-Ming Zhao, Ru-Xia Zhang, Jie Chen, Ling Zhou
Summary: The translation introduces a new and efficient method for synthesizing axially chiral aryl-C3-benzoindoles, explaining the success of the strategy in detail.
Article
Chemistry, Multidisciplinary
Stuart C. D. Kennington, Saul F. Teloxa, Miguel Mellado-Hidalgo, Oriol Galeote, Sabrina Puddu, Marina Bellido, Pedro Romea, Felix Urpi, Gabriel Aullon, Merce Font-Bardia
Summary: A direct and asymmetric aldol reaction of N-acyl thiazinanethiones with aromatic aldehydes catalyzed by chiral nickel(II) complexes was reported. The reaction gives high yields of O-TIPS-protected anti-aldol adducts with remarkable stereocontrol and atom economy. The removal of the achiral scaffold provides enantiomerically pure intermediates with synthetic interest for producing anti-alpha-amino-beta-hydroxy and alpha,beta-dihydroxy carboxylic derivatives, with theoretical calculations explaining the observed high stereocontrol.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Yujiro Hayashi
Summary: The aldol reaction is a significant carbon-carbon bond-forming reaction in organic chemistry. The use of trifluoromethyl-substituted diarylprolinol as an organocatalyst has been found to be effective in promoting cross-aldol reactions with excellent selectivities.
Article
Chemistry, Inorganic & Nuclear
Dikin Patel, Komal A. Trivedi, Himanshu Srivastava, Sanjeev R. Kane, Chetan K. Modi
Summary: In this study, we fabricated a novel nano-catalyst FeNPs/DETA@rGO with a dual activation mechanism. The catalyst exhibits excellent characteristics in terms of both base and acid properties, enabling efficient catalysis of carbon-carbon bond formation. Moreover, the catalyst showed good stability even after multiple cycles of recycling.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Review
Chemistry, Multidisciplinary
Sofiya Runikhina, Dmitry Eremin, Denis Chusov
Summary: Efficient formation of saturated carbon-carbon bonds is crucial in organic synthesis, and reductive aldol-type reactions have gained increasing interest for their versatile applications. This review highlights the advantages and disadvantages of these reactions in total synthesis of pharmaceutical substances to encourage further research in the field.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Physical
Pablo J. Luggren, Liza A. Dosso, J. Isabe Di Cosimo
Summary: The feasibility of using Zn-Zr mixed oxides for gas-phase production of olefins from butyric acid was investigated. The composition of the catalyst and experimental conditions play a crucial role in determining the olefin yield.
APPLIED CATALYSIS A-GENERAL
(2022)
Article
Chemistry, Organic
Yuvraj Garg, James Osborne, Serhii Vasylevskyi, Nivedha Velmurugan, Fujie Tanaka
Summary: 1,3-Diamine-derived catalysts were synthesized and utilized in asymmetric Mannich reactions of ketones. The Mannich products with high enantioselectivities were obtained under mild conditions through catalysis by one of the 1,3-diamine derivatives in the presence of acids. Bond formation primarily occurred at the less-substituted α-position of the ketone carbonyl group. The primary and tertiary amines of the 1,3-diamine derivative cooperatively acted for the catalysis.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Along Ma, Wenjun Du, Jiawei Wang, Kefan Jiang, Cheng Zhang, Wenhan Sheng, Haiyan Zheng, Rongchao Jin, Shuxin Wang
Summary: Chirality has become a popular topic in materials research recently, and obtaining enantiopure materials remains a challenge. In this study, homochiral nanoclusters were obtained through a recrystallization strategy without any chiral factors. The configuration of silver nanoclusters in solution rapidly flipped, converting the initial racemic nanoclusters to homochiral ones as confirmed by X-ray crystallography. These enantiopure nanoclusters can be used as amplifiers for detecting chiral carboxylic drugs.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Organic
Tolga A. Yesil, Taner Atalar, Mustafa Yavuz, Erkan Erturk
Summary: Effective synthesis of prolinamides of 2-(2-aminocyclohexyl)phenols was achieved. The novel prolinamides were found to catalyze the direct aldol reaction between ketones and aldehydes with high stereoselectivity, resulting in up to 99:1 anti/syn diastereomeric and 99:1 enantiomeric ratios. Experimental and computational studies revealed that the electrophile (e.g. aldehyde) was activated through dual hydrogen bonding with the amide NH and phenolic OH group of the catalyst. The most enantioselective catalyst exhibited remarkable structural features of rather large spacing between the H-bond donor groups and conformational flexibility.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Physical
Liangliang Zhang, Martin Oestreich
Summary: The passage describes a reaction sequence involving enantioselective copper-catalyzed conjugate silylation and diastereotopic group-selective aldol cyclization. The intramolecular aldol reaction's diastereoselectivity depends on the silicon nucleophile used, and the more basic zinc reagent enables thermodynamically driven cis-to-trans isomerization. A wide range of electron-withdrawing groups, including electron-deficient heterocycles, are compatible with the different procedures developed.
Article
Chemistry, Multidisciplinary
Ekta Shah, Paramita Mahapatra, Ashutosh V. Bedekar, Hemant P. Soni
Article
Chemistry, Multidisciplinary
Ekta Shah, Pratik Upadhyay, Mala Singh, Mohmmad Shoab Mansuri, Rasheedunnisa Begum, Navin Sheth, Hemant P. Soni
NEW JOURNAL OF CHEMISTRY
(2016)
Article
Chemistry, Organic
Sanjiv O. Tomer, Hemant P. Soni
ORGANIC & BIOMOLECULAR CHEMISTRY
(2017)
Article
Chemistry, Analytical
Jitendra Wagh, Kuldeep J. Patel, Parth Soni, Krutika Desai, Pratik Upadhyay, Hemant P. Soni
Article
Chemistry, Multidisciplinary
Ekta Shah, Ashlesha Kadam, Tina Jubin, Rasheedunnisa Begum, Pratik Upadhyay, Hemant P. Soni
Article
Chemistry, Multidisciplinary
Hemanshu A. Patel, Akash Gutal, Suban K. Sahoo, Hemant P. Soni
Article
Nanoscience & Nanotechnology
Hiren K. Machhi, Keval K. Sonigara, Sanjay N. Bariya, Hemant P. Soni, Saurabh S. Soni
Summary: The rechargeable aqueous zinc-iodine batteries (AZIBs) with a multipurpose sponge-like porous matrix of a metal-organic gel show superior electrochemical performance due to limited iodine diffusion, leading to high capacity retention and long-term stability even after 1500 cycles. Prototype flexible band-aid-type AZIBs also demonstrate promising performance in real-scale wearable applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Neelam Gupta, Hiren K. Machhi, Bhumi A. Baraiya, Saurabh S. Soni, Ashutosh Bedekar, Prafulla K. Jha, Hemant P. Soni
Summary: Octahedral-shaped Cu2O nanocrystals were synthesized and used as catalyst for benzylic sp(3) C-H bond oxidation. The oxidation of Cu2O to CuO can be avoided in the dark or inert atmosphere or continuous flow of oxygen gas. The proposed reaction mechanism involves activation of O-2 molecule through single electron transfer (SET) mechanism on the (111) facets of semiconducting Cu2O NCs in light.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Sanjiv O. Tomer, Hemant P. Soni
Summary: In this study, the molecular structure of quinidine was modified and a chiral hemiester catalyst with high enantioselectivity and yield was successfully synthesized.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Physical
Neelam Gupta, Bhumi A. Baraiya, Prafulla K. Jha, Hemant P. Soni
Summary: In this study, Cu2O nanocrystals were synthesized with different morphologies and their photocatalytic activity towards organic substrates was explored. The reaction mechanism involving specific surfaces of Cu2O nanocrystals was proposed based on chemical kinetics experiments, electrochemical analyses, and DFT calculations. The cubic morphology showed the highest activity.
MOLECULAR CATALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Bindi Sanghavi, Sucheta De Mondal, Urja Verma, Suresh Balakrishnan, Sk Riyajuddin, Kaushik Ghosh, Mitesh Sarkar, Hemant P. P. Soni
Summary: L-arginine capped and transition metal-doped Ultra-Small Iron Oxide Nanoparticles (USIONs) were synthesized and encapsulated with Pluronic F127((R)) as a drug delivery vehicle. The drug release kinetics showed significant release in 5 hours and 72 hours, with different release rates for different metal-doped vehicles. The nanoparticles exhibited contrasting ability for Magnetic Resonance Imaging (MRI), with a shift from T-2 to T-1 contrasting at lower concentrations.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Bindi Sanghavi, Hemant P. Soni
Summary: Fe3O4@L-Arginine and Fe3O4@L-Histidine nanoparticles were synthesized and used as catalysts for sequential Knoevenagel condensation and Michael addition reactions. Optimized reaction parameters resulted in high yields of 97% in Knoevenagel adducts and 70% in Michael products under solvent-free conditions at 80 degrees C. However, Fe3O4@L-Histidine NPs did not show any catalytic activity for the sequential Michael addition. The reasons behind the high activities of Fe3O4@L-Arginine NPs have been discussed, and the catalyst could be reused for 5 cycles with consistent activity and selectivity. This optimized protocol offers high isolated yields, cost savings in solvents, and falls within the domain of green chemistry.
RESEARCH ON CHEMICAL INTERMEDIATES
(2023)
Article
Chemistry, Physical
Sanjiv O. Tomer, Hemant P. Soni
CATALYSIS SCIENCE & TECHNOLOGY
(2019)
Article
Engineering, Environmental
Ekta Shah, Jayraj V. Vaghasiya, Saurabh S. Soni, C. J. Panchal, Priya S. Suryavanshi, Mukesh Chavda, Hemant P. Soni
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2016)
Article
Engineering, Environmental
Namrata Dixit, Jayraj V. Vaghasia, Saurabh S. Soni, Mitesh Sarkar, Mukesh Chavda, Naveen Agrawal, Hemant P. Soni
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2015)