Review
Immunology
Jun Wang, Miriam Erlacher, Juncal Fernandez-Orth
Summary: Under inflammatory conditions, steady-state hematopoiesis switches to emergency myelopoiesis, leading to different forms of cell death and other changes in the hematopoietic system, ultimately causing loss of hematopoiesis function. In individuals with inherited bone marrow failure syndromes or immune-mediated aplastic anemia, chronic inflammatory signals may aggravate disease progression.
FRONTIERS IN IMMUNOLOGY
(2022)
Editorial Material
Chemistry, Physical
Ida Sognnaes
Summary: In a new paper published in Nature Energy, Odenweller et al. analyze the feasibility of green hydrogen supply using uncertainty analysis. Their findings indicate that despite the rapid growth in electrolysis capacity similar to wind and solar power, the availability of green hydrogen will remain scarce in the short term and uncertain in the long term.
Article
Dermatology
Judith Agudo
Summary: The skin acts as a barrier to prevent dehydration and protect us from pathogens. It contains various stem cell populations essential for maintenance and repair, as well as a strong immune response that can lead to autoimmune diseases and skin cancers. Understanding the interactions between immune cells and skin stem cells is crucial for developing new therapeutic strategies for autoimmunity and cancer.
EXPERIMENTAL DERMATOLOGY
(2021)
Editorial Material
Biology
Julia A. Schwartzman
Summary: The Western honey bee serves as a model system for studying how different species of bacteria can coexist in a single community.
Article
Environmental Sciences
Maria Elena Crespo-Lopez, Marcus Augusto-Oliveira, Amanda Lopes-Araujo, Leticia Santos-Sacramento, Priscila Yuki Takeda, Barbarella de Matos Macchi, Jose Luiz Martins do Nascimento, Cristiane S. F. Maia, Rafael R. Lima, Gabriela P. Arrifano
Summary: Mercury is among the top ten most dangerous chemicals for public health worldwide, with increasing emissions particularly in South America, notably the Amazon region. Human populations in this area are highly exposed to methylmercury through contaminated fish consumption, with levels far exceeding those of other regions globally.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Business, Finance
Dan Zhang, Biangxiang Li
Summary: This paper investigates the predictive power of the financial stress index for stock returns and finds that it is efficient in predicting stock returns. Additionally, the financial stress index provides incremental information compared to traditional macroeconomic variables. The study also reveals that the financial stress index achieves the highest CER and SR gains among the predictors, considering different investor risk aversion coefficients.
FINANCE RESEARCH LETTERS
(2022)
Review
Biochemistry & Molecular Biology
Zaida L. Almeida, Rui M. M. Brito
Summary: Protein aggregation and the formation of insoluble amyloid fibrils are intrinsic characteristics of amyloid diseases. Soluble oligomeric species formed during amyloid formation are highly cytotoxic and can lead to cell death and organ dysfunction. Disassembling preformed amyloids is a potential therapeutic strategy to arrest the progression of organ deterioration in amyloidosis. In this review, various chemical and biochemical agents capable of disaggregating amyloids are discussed, including their mode of action, structure, interactions with fibrillar structures, toxicity, and potential as treatment options.
Review
Chemistry, Multidisciplinary
Sara Maslanka Figueroa, Daniel Fleischmann, Achim Goepferich
Summary: Viruses, as nanomaterials, possess unique properties that allow for efficient infection of host cells and evasion of the immune system. While there have been efforts to mimic viral traits to improve nanomaterial performance, a comprehensive evaluation of the impact of virus-mimetic material design on the targeting efficiency of nanomaterials is currently lacking.
JOURNAL OF CONTROLLED RELEASE
(2021)
Review
Cell Biology
Qilin Guo, Anja Scheller, Wenhui Huang
Summary: NG2 glia primarily serve as progenitors for oligodendrocytes and a subpopulation of astrocytes, with the differentiation potential showing age- and region-dependent heterogeneity. Inconsistent findings in various transgenic mouse lines in previous studies may be attributed to putative reasons that need further discussion.
NEURAL REGENERATION RESEARCH
(2021)
Article
Green & Sustainable Science & Technology
Kristian Hoelscher, Hanne Cecilie Geirbo, Lisbet Harboe, Sobah Abbas Petersen
Summary: The transition towards urban living poses challenges and vulnerabilities. Despite the crises cities face, innovative policies and practices can emerge to support urban resilience and sustainable development. Knowledge and practices from urban crisis contexts offer valuable insights for addressing urban challenges.
Review
Nutrition & Dietetics
Rachelle S. Opie, Felice N. Jacka, Wolfgang Marx, Tetyana Rocks, Claire Young, Adrienne O'Neil
Summary: Lifestyle factors are important for treating common mental disorders, and it is crucial to integrate lifestyle interventions into clinical practice. This paper discusses the utility and scale-up of lifestyle interventions for common mental disorders and identifies enablers and barriers to translation efforts by drawing on diabetes prevention literature.
Article
Biochemistry & Molecular Biology
Wenbo Pan, Weiwei Li, Lijing Liu, Huawei Zhang
Summary: Viruses cause severe diseases in plants and animals, prompting exploration of new antiviral strategies. Some animals like bats are predicted natural reservoirs of multiple viruses and possess broad-spectrum antiviral capabilities. Disruption of the AtTHFS gene enhances plant resistance to different plant viruses, suggesting a novel antiviral strategy for plant breeding.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2022)
Review
Computer Science, Interdisciplinary Applications
Grace C. Y. Peng, Mark Alber, Adrian Buganza Tepole, William Cannon, Suvranu De, Salvador Dura-Bernal, Krishna Garikipati, George Karniadakis, William W. Lytton, Paris Perdikaris, Linda Petzold, Ellen Kuhl
Summary: Machine learning excels in image recognition in fields like biomedicine, but struggles with sparse data. Integrating machine learning with multiscale modeling can create more efficient biological system models, benefiting both approaches.
ARCHIVES OF COMPUTATIONAL METHODS IN ENGINEERING
(2021)
Review
Plant Sciences
Przemyslaw Prusinkiewicz, Teng Zhang, Andrew Owens, Mikolaj Cieslak, Paula Elomaa
Summary: This study investigates the phyllotactic patterns in fasciated flower heads in the Asteraceae plant family, highlighting the differences and problems in non-circular phyllotaxis. The findings suggest that some concepts, such as parastichies and parastichy numbers, maintain their significance in non-circular phyllotaxis, while others, like the divergence angle, need to be extended or lose their role. These observations identify several open problems related to phyllotaxis that could be addressed through further studies of fasciated heads.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Review
Cell Biology
Hongyu Li, Lixiong Gao, Jinlin Du, Tianju Ma, Zi Ye, Zhaohui Li
Summary: Organoids, derived from 3D culture systems, serve as a crucial bridge between 2D cell cultures and in vivo animal models, showing promising applications in various fields. However, current organoids lack some essential components found in tissues, such as blood vessels and communication with surrounding tissues. On the other hand, teratomas, a recently discovered in vivo model, exhibit complex tissue-like organization and can mimic multilineage human development. This unique characteristic of teratomas provides opportunities to promote vascularization and maturation of organoids within an in vitro 3D culture system.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
