Article
Medicine, General & Internal
David R. Jacobs, Jessica G. Woo, Alan R. Sinaiko, Stephen R. Daniels, Johanna Ikonen, Markus Juonala, Noora Kartiosuo, Terho Lehtimaki, Costan G. Magnussen, Jorma S. A. Viikari, Nanhua Zhang, Lydia A. Bazzano, Trudy L. Burns, Ronald J. Prineas, Julia Steinberger, Elaine M. Urbina, Alison J. Venn, Olli T. Raitakari, Terence Dwyer
Summary: This prospective cohort study found that childhood cardiovascular risk factors, including BMI, systolic blood pressure, lipid levels, and smoking, were associated with cardiovascular events in adulthood. Childhood risk factors and the change in risk score between childhood and adulthood were associated with midlife cardiovascular events.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Editorial Material
Medicine, General & Internal
Julie R. Ingelfinger
Summary: While atherosclerosis has been found on postmortem examination of youths, there is a lack of direct evidence linking childhood cardiovascular risk factors to adult cardiovascular disease outcomes.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Health Care Sciences & Services
Yeong Chan Lee, Jiho Cha, Injeong Shim, Woong-Yang Park, Se Woong Kang, Dong Hui Lim, Hong-Hee Won
Summary: In this study, an artificial intelligence model was developed to identify cardiovascular disease using multimodal data including clinical risk factors and fundus photographs. The model achieved high accuracy in both validation datasets and suggested that fundus photography can serve as a possible predictive marker for CVD.
NPJ DIGITAL MEDICINE
(2023)
Article
Clinical Neurology
Jaime M. Hatcher-Martin, Neil A. Busis, Bruce H. Cohen, Rebecca A. Wolf, Elaine C. Jones, Eric R. Anderson, Joseph Fritz, Steven J. Shook, Riley M. Bove
Summary: Telehealth services are seen as a complement to in-person neurologic care, with a focus on supporting patient access regardless of location. The American Academy of Neurology advocates for coverage of telehealth services by all subscriber benefits, equitable provider reimbursement, simplified state licensing requirements, and expanding telehealth research and quality initiatives. Roles and responsibilities of providers should be clearly defined in telehealth service models.
Article
Clinical Neurology
James A. Russell, John C. Hutchins, Leon G. Epstein
Summary: The Code of Professional Conduct developed by the American Academy of Neurology aims to formalize the standards of professional behavior for AAN members, guiding them in providing high-quality patient-centered neurologic care.
Article
Clinical Neurology
James A. Russell, John C. Hutchins, Leon G. Epstein
Summary: The AAN Code of Professional Conduct formalizes standards for behavior among members to ensure high-quality patient-centered neurologic care.
Article
Pediatrics
Michael Khoury, Philip Khoury, Lydia Bazzano, Trudy L. Burns, Stephen Daniels, Terence Dwyer, Johanna Ikonen, David R. Jr Jr Jacobs, Markus Juonala, Mika Kahonen, Ronald Prineas, Olli T. Raitakari, Julia Steinberger, Alison Venn, Jorma Viikari, Jessica G. Woo, Alan Sinaiko, Elaine M. Urbina
Summary: The 2017 American Academy of Pediatrics hypertension Clinical Practice Guideline increased the prevalence of childhood hypertension and improved sensitivity in predicting adult hypertension, but did not overall strengthen the association.
JOURNAL OF PEDIATRICS
(2022)
Article
Clinical Neurology
David B. Burkholder, Christopher J. Boes
Summary: Robert Wartenberg had a successful career in medicine and played a crucial role in the establishment of the American Academy of Neurology. His strong personality and academic standing made him a valuable asset to the young leaders in neurology.
Review
Cell Biology
Giulia Germena, Laura Cecilia Zelarayan, Rabea Hinkel
Summary: Exosomes are small membranous vesicles that contain biological material and can mediate cell-to-cell communication, maintaining homeostasis or modulating disease processes. They play a crucial role in cardiovascular diseases and have potential diagnostic value, although their specific physiological and pathophysiological functions in the cardiovascular system are still not fully understood.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Natalie R. Hasbani, Symen Ligthart, Michael R. Brown, Adam S. Heath, Allison Bebo, Kellan E. Ashley, Eric Boerwinkle, Alanna C. Morrison, Aaron R. Folsom, David Aguilar, Paul S. de Vries
Summary: This study aimed to investigate the impact of polygenic risk and lifestyle on the lifetime risk of coronary heart disease (CHD). The findings showed that adherence to the American Heart Association's Life's Simple 7 (LS7) guidelines was associated with a lower lifetime risk of CHD, especially in individuals with high genetic susceptibility. Adherence to LS7 guidelines contributed more to the lifetime risk of CHD in Black participants. Therefore, improved polygenic risk scores are needed to accurately evaluate genetic susceptibility for CHD in diverse populations.
Review
Immunology
Maria Teresa Palano, Martina Cucchiara, Matteo Gallazzi, Federica Riccio, Lorenzo Mortara, Gian Franco Gensini, Gaia Spinetti, Giuseppe Ambrosio, Antonino Bruno
Summary: Atherosclerosis, the leading cause of cardiovascular disease worldwide, is influenced not only by dyslipidemia but also chronic inflammation and immune system abnormalities. Natural killer cells, an understudied immune cell type, may play a role in vascular homeostasis and offer potential for new therapies. Understanding the pathophysiology of natural killer cells in atherosclerosis and associated risk factors could lead to preventive and treatment strategies.
FRONTIERS IN IMMUNOLOGY
(2022)
Editorial Material
Microbiology
Arturo Casadevall, Peggy A. Cotter, Lynn Enquist, Timothy J. Donohue, Stefano Bertuzzi, Nguyen K. Nguyen
Summary: This article discusses the transformation of the American Academy of Microbiology into a scientific think tank at ASM while maintaining its standards as an honorific community of scholars from 2019-2023.
Article
Clinical Neurology
Merel S. Ekker, Jamie I. Verhoeven, Mijntje M. I. Schellekens, Esther M. Boot, Mayte E. van Alebeek, Paul J. A. M. Brouwers, Renate M. Arntz, Gert W. van Dijk, Rob A. R. Gons, Inge W. M. van Uden, Tom den Heijer, Paul L. M. de Kort, Karlijn F. de Laat, Anouk G. W. van Norden, Sarah E. Vermeer, Marian S. G. van Zagten, Robert J. van Oostenbrugge, Marieke J. H. Wermer, Paul J. Nederkoorn, Thomas P. Zonneveld, Henk Kerkhoff, Fergus A. Rooyer, Frank G. van Rooij, Ido R. van den Wijngaard, Catharina J. M. Klijn, Anil M. Tuladhar, Frank-Erik de Leeuw
Summary: The study aims to identify risk factors and possible causes of cryptogenic ischemic stroke in young adults using a pediatric classification system. The results show that using the pediatric classification system provides new leads for the possible causes in cryptogenic stroke, and could potentially lead to more tailored treatment for young individuals with stroke.
Article
Pediatrics
Caroline M. Sierra, Alice Park, Eunsi Eum, Giselle Garcia, Mireya Lopez, Shawnee N. Daniel, Khaled Bahjri, Kristine A. Parbuoni
Summary: Approximately half of the patients received palivizumab prophylaxis in accordance with the 2014 AAP recommendations and infrequently suffered from a breakthrough RSV infection.
PEDIATRIC PULMONOLOGY
(2021)
Article
Orthopedics
Nicolas S. Piuzzi, David Ring
Summary: The Major Extremity Trauma and Rehabilitation Consortium and AAOS have developed criteria for addressing mental and social health opportunities to help patients recover from musculoskeletal injuries. The criteria, developed by experts and clinicians, were rated by a multidisciplinary voting panel to determine the appropriateness of treatment, with a high level of agreement achieved.
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
(2021)
Article
Peripheral Vascular Disease
Natalie A. Bello, Byron C. Jaeger, John N. Booth, Marwah Abdalla, D. Edmund Anstey, Daniel N. Pugliese, Cora E. Lewis, Samuel S. Gidding, Donald Lloyd-Jones, Sanjiv J. Shah, Joseph E. Schwartz, James M. Shikany, Paul Muntner, Daichi Shimbo
JOURNAL OF HYPERTENSION
(2020)
Article
Statistics & Probability
Aisha Betoko, Chike Nwabuo, Bharath Ambale Venkatesh, Erin P. Ricketts, Sejong Bae, Colin Wu, Samuel S. Gidding, Kiang Liu, Joao A. C. Lima, Christopher Cox
JOURNAL OF APPLIED STATISTICS
(2020)
Article
Cardiac & Cardiovascular Systems
Henrique T. Moreira, Henrique D. Vasconcellos, Bharath Ambale-Venkatesh, Evan L. Brittain, Chike C. Nwabuo, Andre Schmidt, Donald M. Lloyd-Jones, John J. Carr, Cora E. Lewis, David R. Jacobs, Samuel S. Gidding, Joao A. C. Lima
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2020)
Review
Cardiac & Cardiovascular Systems
Gerald F. Watts, Samuel S. Gidding, Pedro Mata, Jing Pang, David R. Sullivan, Shizuya Yamashita, Frederick J. Raal, Raul D. Santos, Kausik K. Ray
NATURE REVIEWS CARDIOLOGY
(2020)
Review
Cardiac & Cardiovascular Systems
Katherine A. Wilemon, Jasmine Patel, Carlos Aguilar-Salinas, Catherine D. Ahmed, Mutaz Alkhnifsawi, Wael Almahmeed, Rodrigo Alonso, Khalid Al-Rasadi, Lina Badimon, Luz M. Bernal, Martin P. Bogsrud, Lynne T. Braun, Liam Brunham, Alberico L. Catapano, Kristyna Cillikova, Pablo Corral, Regina Cuevas, Joep C. Defesche, Olivier S. Descamps, Sarah de Ferranti, Jean-Luc Eisele, Gerardo Elikir, Emanuela Folco, Tomas Freiberger, Francesco Fuggetta, Isabel M. Gaspar, Akos G. Gesztes, Urh Groselj, Ian Hamilton-Craig, Gabriele Hanauer-Mader, Mariko Harada-Shiba, Gloria Hastings, G. Kees Hovingh, Maria C. Izar, Allison Jamison, Gunnar N. Karlsson, Meral Kayikcioglu, Sue Koob, Masahiro Koseki, Stacey Lane, Marcos M. Lima-Martinez, Greizy Lopez, Tania L. Martinez, David Marais, Letrillart Marion, Pedro Mata, Inese Maurina, Diana Maxwell, Roopa Mehta, George A. Mensah, Andre R. Miserez, Dermot Neely, Stephen J. Nicholls, Atsushi Nohara, Borge G. Nordestgaard, Leiv Ose, Athanasios Pallidis, Jing Pang, Jules Payne, Amy L. Peterson, Monica P. Popescu, Raman Puri, Kausik K. Ray, Ashraf Reda, Tiziana Sampietro, Raul D. Santos, Inge Schalkers, Laura Schreier, Michael D. Shapiro, Eric Sijbrands, Daniel Soffer, Claudia Stefanutti, Mario Stoll, Rody G. Sy, Martha L. Tamayo, Myra K. Tilney, Lale Tokgozoglu, Brian Tomlinson, Antonio J. Vallejo-Vaz, Alejandra Vazquez-Cardenas, Patricia Vieira de Luca, David S. Wald, Gerald F. Watts, Nanette K. Wenger, Michaela Wolf, David Wood, Aram Zegerius, Thomas A. Gaziano, Samuel S. Gidding
Review
Cardiac & Cardiovascular Systems
Holly C. Gooding, Samuel S. Gidding, Andrew E. Moran, Nicole Redmond, Norrina B. Allen, Fida Bacha, Trudy L. Burns, Janet M. Catov, Michael A. Grandner, Kathleen Mullan Harris, Heather M. Johnson, Michaela Kiernan, Tene T. Lewis, Karen A. Matthews, Maureen Monaghan, Jennifer G. Robinson, Deborah Tate, Kirsten Bibbins-Domingo, Bonnie Spring
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2020)
Editorial Material
Peripheral Vascular Disease
Samuel S. Gidding
Article
Cardiac & Cardiovascular Systems
Samuel S. Gidding, Laura A. Colangelo, Chike C. Nwabuo, Cora E. Lewis, David R. Jacobs, Pamela J. Schreiner, Joao A. C. Lima, Norrina B. Allen
Summary: The PDAY risk score based on post-mortem measurements was found to be highly predictive of future ASCVD events in young adults. The presence of coronary artery calcium improved risk prediction only if the score was 0. Cumulative risk exposure and PDAY score at age 18-30 were also significant factors for predicting ASCVD.
EUROPEAN HEART JOURNAL
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Urh Groselj, Albert Wiegman, Samuel S. Gidding
EUROPEAN HEART JOURNAL
(2022)
Editorial Material
Hematology
Samuel S. Gidding, Robert A. Hegele
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Samuel S. Gidding, Albert Wiegman, Urh Groselj, Tomas Freiberger, Noel Peretti, Kanika Dharmayat, Magdalena Daccord, Nicola Bedlington, Jaka Sikonja, Kausik K. Ray, Raul D. Santos, Martin Halle, Lale Tokgozoglu, Inaki Gutierrez-Ibarluzea, Fausto J. Pinto, Marius Geanta
Summary: Familial hypercholesterolaemia (FH) is often overlooked and undertreated in Europe, resulting in increased risk of premature heart disease. Early treatment is effective in preventing heart disease and cost-effective. The European Commission Public Health Best Practice Portal recognizes FH screening as an effective strategy. Model programs in Europe employ cascade screening, universal screening, opportunistic screening, or a combination of these approaches to identify young individuals with FH. Recommendations to improve FH identification emphasize the need for screening programs in every country, adapted to fit the healthcare system, with financial support from governments and further research for optimization.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Vinithra Varadarajan, Samuel S. Gidding, Colin Wu, J. Jeffrey Carr, Joao A. C. Lima
Summary: The increasing prevalence of obesity, hypertension, and diabetes, along with worsening environmental factors, has led to a growing burden of cardiovascular diseases worldwide. Noninvasive imaging techniques, including vascular ultrasound, echocardiography, and magnetic resonance imaging, play a significant role in identifying early cardiovascular disease phenotypes. This article reviews the various imaging modalities used for the evaluation, characterization, and quantification of early subclinical cardiovascular diseases.
CIRCULATION RESEARCH
(2023)
Article
Hematology
Alexander S. F. Berry, Laney K. Jones, Eric J. Sijbrands, Samuel S. Gidding, Matthew T. Oetjens
Summary: This study found that genetic subtyping based on monogenic familial hypercholesterolemia and Lp(a) provides better stratification of 10-year incident CAD risk than LDL-C-based stratification in individuals with severe hypercholesterolemia.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Samuel S. Gidding, H. Lester Kirchner, Andrew Brangan, William Howard, Melissa A. Kelly, Kelly D. Myers, Kelly M. Morgan, Matthew T. Oetjens, Timothy C. Shuey, David Staszak, Natasha T. Strande, Nicole L. Walters, Kristen D. D. Yu, Katherine A. Wilemon, Marc S. Williams, Amy C. Sturm, Laney K. Jones
Summary: This study aimed to identify patients suspected of familial hypercholesterolemia (FH) using data mining of electronic health records. However, the absence of both phenotypic and genomic data in the same cohort limited the study.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Public, Environmental & Occupational Health
Laney K. Jones, Samuel S. Gidding, Terry L. Seaton, Anne Goldberg, Christina Gregor, Amy C. Sturm, Ross C. Brownson, Alanna Kulchak Rahm, Marc S. Williams
RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY
(2020)