Article
Psychiatry
J. M. Batail, I. Corouge, B. Combes, C. Conan, M. Guillery-Sollier, M. Verin, P. Sauleau, F. Le Jeune, J. Y. Gauvrit, G. Robert, C. Barillot, J. C. Ferre, D. Drapier
Summary: This study investigated the neurovascular mechanisms underlying apathy in depression using neuroimaging techniques. The results showed a negative correlation between cerebral blood flow in the left anterior cingulate cortex (ACC) and the severity of apathy, highlighting the significance of this region in depressed individuals.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Manuel Taso, Veronica Aramendia-Vidaurreta, Erin K. K. Englund, Susan Francis, Suzanne Franklin, Ananth J. J. Madhuranthakam, Petros Martirosian, Krishna S. S. Nayak, Qin Qin, Xingfeng Shao, David L. L. Thomas, Zungho Zun, Maria A. A. Fernandez-Seara
Summary: This review article provides an overview of the developments and challenges in arterial spin labeling (ASL) perfusion imaging in the body outside of the brain. Specific challenges and developments in various body locations, including kidneys, lungs, heart, placenta, eye, liver, pancreas, and muscle, are discussed. The article also explores the possibilities of wider adoption of body ASL in clinical practice based on standardization efforts and recent advances in high/low-field systems and machine-learning.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Review
Oncology
Abir Troudi, Fatima Tensaouti, Eloise Baudou, Patrice Peran, Anne Laprie
Summary: This article introduces the magnetic resonance imaging techniques for pediatric brain tumors, especially the ASL MRI technique in evaluating treatment response and neurocognitive sequelae. ASL is a noninvasive technique for measuring cerebral blood flow, but it has some drawbacks and technical requirements.
Article
Neurosciences
Yan Sun, Yujie Liu, Wenwen Yu, Yumin Zhong
Summary: This study examined the deep gray matter perfusion in neonates with congenital heart disease (CHD) using arterial spin labeling magnetic resonance imaging. The results showed that neonates with cyanotic CHD had lower perfusion in the right thalamus compared to controls, and lower perfusion in the right basal ganglia compared to acyanotic CHD. When the CHD group was considered as a whole, there was a slight decrease in perfusion in the left thalamus compared to controls. These findings suggest that cardiac physiology plays an important role in regional cerebral perfusion changes. Arterial spin labeling perfusion may be a useful marker for assessing the risk of impaired cerebral blood flow auto-regulation and cerebral hypoperfusion in neonates with CHD.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Sven Bambach, Mark Smith, P. Pearse Morris, Norbert G. Campeau, Mai-Lan Ho
Summary: Arterial spin labeling (ASL) is a noncontrast MRI technique used for quantitative evaluation of brain perfusion. This article discusses advanced applications of ASL across the lifespan, presenting case examples from children and adults with various pathologies. The article highlights the subtleties and pitfalls of ASL interpretation.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Veterinary Sciences
Anne-Cecile Hoffmann, Yannick Ruel, Kirsten Gnirs, Stella Papageorgiou, Luca Zilberstein, Sarah Nahmani, Nathalie Boddaert, Hugues Gaillot
Summary: The study tested the feasibility of ASL using a 1.5 Tesla scanner in dogs and cats, providing recommendations for optimal quantification of cerebral blood flow. By implementing ASL sequences and optimizing CBF, valuable values for the characterization of various brain diseases in dogs and cats were obtained.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lei Zhang, Danfeng Xie, Yiran Li, Aldo Camargo, Donghui Song, Tong Lu, Jean Jeudy, David Dreizin, Elias R. Melhem, Ze Wang
Summary: This study evaluated the transferability of a DL-based ASL MRI denoising method across different image sequences and populations, finding that DLASL outperformed traditional methods on different datasets, significantly improving image quality, and enhancing the detection of AD-related hypoperfusion patterns.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyun-Seo Ahn, Yujin Jung, Sung-Hong Park
Summary: A new two-compartment renal perfusion model was proposed to calculate glomerular blood transfer rate as a measure of renal function. Using diffusion-weighted arterial spin labeling, it was shown that caffeine significantly increased cortical glomerular blood transfer rate compared to control, indicating its sensitivity in monitoring vasodilation.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Peripheral Vascular Disease
Ian Seiller, Aude Pavilla, Julien Ognard, Nathalie Ozier-Lafontaine, Sylvie Colombani, Yamilet Cepeda Ibarra, Mehdi Mejdoubi
Summary: Using arterial spin-labeling-MRI, this study found significantly different cerebral blood flow reactions to a head-down tilt dynamic maneuver in hypertensive patients compared to normotensive individuals, supporting the hypothesis that hypertension is responsible for deficient cerebrovascular autoregulation.
JOURNAL OF HYPERTENSION
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Christina. L. L. Herrera, Yiming Wang, Durga Udayakumar, Yin Xi, Quyen. N. N. Do, Matthew. A. A. Lewis, David. M. M. Owen, Baowei Fei, Catherine. Y. Y. Spong, Diane. M. M. Twickler, Ananth. J. J. Madhuranthakam
Summary: This study evaluates placental perfusion in normal pregnancies and pregnancies affected by chronic hypertension using pseudo-continuous arterial spin-labeled (pCASL) MRI. The results show a decline in placental perfusion in the second trimester of normal pregnancies, while it remained unchanged in cHTN pregnancies. Additionally, significantly lower placental perfusion was observed in pregnancies with infants that were small for gestational age. Therefore, pCASL-MRI-measured perfusion may serve as an effective imaging biomarker for placental insufficiency.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Chien-Hung Lin, Tsyh-Jyi Hsieh, Yi-Chen Chou, Clement Kuen-Huang Chen
Summary: This study evaluated the performance of arterial spin labeling (ASL) in imaging musculoskeletal tumors and found that ASL can detect high tissue blood flow (TBF) in malignant tumors and hypervascular benign lesions. It is recommended to use a longer post-labeling delay (PLD) to differentiate musculoskeletal tumors.
Article
Clinical Neurology
Vivek Srikar Yedavalli, Omar Hamam, Mona Bahouth, Victor Cruz Urrutia, Amara Ahmed, Hanzhang Lu, Craig Jones, Licia Pacheco Luna, Haris Iqbal Sair, Bryan Lanzman
Summary: Autoimmune encephalitis (AE) is a rare group of diseases, and anti-leucine-rich glioma inactivated 1 (LGI1) encephalitis is one subtype. Accurate diagnosis of LGI1 encephalitis is crucial for prompt treatment. Arterial Spin Labeling (ASL) plays a critical role in evaluating stroke and stroke mimics. This study aims to demonstrate the added value of ASL in detecting LGI1 encephalitis for timely diagnosis and treatment.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Osamu Togao, Makoto Obara, Koji Yamashita, Kazufumi Kikuchi, Koichi Arimura, Ataru Nishimura, Akira Nakamizo, Tatsuhiro Wada, Chiaki Tokunaga, Ryoji Mikayama, Yasuo Yamashita, Hiroshi Hamano, Marc Van Cauteren, Kousei Ishigami, Shingo Baba
Summary: This study investigated the usefulness of dynamic PCASL with optimized background suppression for assessing cerebral perfusion in patients with moyamoya disease. The results showed a significant correlation between the CBF measured by dynamic PCASL and SPECT. Additionally, there was a correlation between the ATT measured by dynamic PCASL and the CVR measured by SPECT. Therefore, dynamic PCASL can be used for evaluating cerebral perfusion in moyamoya disease.
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaoyuan Fan, Zhentao Zuo, Tianye Lin, Zhichao Lai, Hui You, Jianxun Qu, Juan Wei, Bao Liu, Feng Feng
Summary: The study aimed to investigate whether preoperative arterial spin labeling (ASL) MRI can predict cerebral hyperperfusion after carotid endarterectomy (CEA) in patients with carotid stenosis. The study found that ASL can non-invasively predict cerebral hyperperfusion after CEA in patients with carotid stenosis based on the presence of arterial transit artifacts (ATAs).
EUROPEAN RADIOLOGY
(2022)
Review
Endocrinology & Metabolism
Dan Huang, Yunlu Guo, Xiaoyu Guan, Lijun Pan, Ziyu Zhu, Zeng'ai Chen, Rick M. Dijkhuizen, Marco Duering, Fang Yu, Johannes Boltze, Peiying Li
Summary: Cognitive impairment (CI) is a significant health concern in aging populations and is often associated with vascular cognitive impairment (VCI). Reduced cerebral blood flow (CBF) plays a critical role in the progression of VCI, and arterial spin labeling (ASL) is a non-invasive MRI technique that can accurately assess CBF. Recent advancements in ASL have improved its usability and led to an increased application in identifying high-risk VCI patients. ASL, when combined with other imaging modalities and biomarkers, shows great potential in early detection and prevention strategies for VCI.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)